Abstract：
:Lacinilene C methyl ether (LCME) is a constituent of the cotton plant and has been implicated as a causative agent of byssinosis. The effect of synthetic LCME on the behavior of isolated strips of canine tracheal smooth muscle (TSM) was examined in tissue bath experiments. LCME (0.64-6.6 x 10(-4) M) caused slowly developing but strong and sustained contractions of TSM strips. Blockade of acetycholine, 5-hydroxytryptamine (5-HT), and histamine H1 receptors with atropine, methysergide, and pyrilamine, respectively, had no effect on constrictions induced by LCME. In contrast, the calcium channel antagonist, verapamil, significantly reduced the response to LCME. Moreover, addition of the beta receptor agonist, isoproterenol, at the peak of LCME-induced contractions relaxed tissues in a concentration-dependent manner. We conclude that LCME elicits contraction of TSM by enhancing the movement of calcium through potential-dependent channels of smooth muscle cell membranes. This mechanism of action does not require activation of specific membrane receptors for acetylcholine, 5-HT, and histamine.
journal_name
Environ Resjournal_title
Environmental researchauthors
Russell JA,McCormick JPdoi
10.1016/s0013-9351(88)80014-8subject
Has Abstractpub_date
1988-02-01 00:00:00pages
118-26issue
1eissn
0013-9351issn
1096-0953pii
S0013-9351(88)80014-8journal_volume
45pub_type
杂志文章abstract：:On May 24-25, 2005 in Ann Arbor, Michigan, the US Environmental Protection Agency, the National Institute of Environmental Health Sciences, and the University of Michigan sponsored a technical workshop on the topic of connecting social and environmental factors to measure and track environmental health disparities. Th...
journal_title：Environmental research
pub_type：
doi：10.1016/j.envres.2005.11.001
更新日期：2006-10-01 00:00:00
abstract：:Accidental contamination of livestock in Michigan in 1973 with polybrominated biphenyls (PBBs) led to the establishment of a registry of exposed individuals in 1976. At the time of enrollment, serum was collected and analyzed for PBBs and polychlorinated biphenyls (PCBs). In 1997, women aged 18 years or older and acti...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.11.010
更新日期：2007-10-01 00:00:00
abstract：:Exposure to perfluorooctane sulfonate (PFOS) is ubiquitous in populations and environments worldwide. Its long half-life in humans, indefinite persistence in the environment, and awareness of its widespread presence in drinking water make the human health assessment of PFOS a priority. While developmental, endocrine, ...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2018.08.004
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Congenital limb deficiencies (CLDs) are a relatively common group of birth defects whose etiology is mostly unknown. Recent studies suggest maternal air pollution exposure as a potential risk factor. AIM:To investigate the relationship between ambient air pollution exposure during early pregnancy and offspr...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108716
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Ambient air pollution is hypothesized to be a risk factor for hypertensive disorders in pregnancy, one of the major pregnancy complications. Past studies have reported the supporting evidence, however this mainly referred to the Western population, and results from trimester-specific analysis have been varie...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.08.024
更新日期：2015-10-01 00:00:00
abstract：:Low doses of mercury (Hg) promote deleterious effects on cardiovascular system, but the mechanisms implicated remain unclear. This study analyzed whether angiotensin II AT-1 receptors are involved in the vascular dysfunction caused by chronic exposure to low HgCl2 doses. For this, rats were divided into four groups an...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.01.026
更新日期：2018-04-01 00:00:00
abstract：:Atopic dermatitis is one of the most common inflammatory skin diseases among children and adults. Although the risk factors for atopic dermatitis have not yet been fully identified, exposure to mercury may be an important environmental risk factor. The objective of this study was to evaluate the association between me...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.02.003
更新日期：2011-05-01 00:00:00
abstract：:Two fish species (Capoeta umbla and Luciobarbus mystaceus) were collected from the Tigris River (Turkey), and tissues (gill, muscle and liver) of fish samples were analyzed for Cd, As, Mn, Cr, Cu, Co and Ni using the inductively coupled plasma-tandem mass spectrometry. Significant differences were present between fish...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109570
更新日期：2020-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(85)90053-2
更新日期：1985-06-01 00:00:00
abstract：:The relationship of inorganic arsenic exposure through drinking water and total urinary arsenic excretion in a nonoccupationally exposed population was evaluated in a cross-sectional study in three mayor cities of Chile (Antofagasta, Santiago, and Temuco). A total of 756 individuals in three population strata (elderly...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.02.007
更新日期：2005-06-01 00:00:00
abstract：:The study was conducted to correlate the consumption frequency of different food groups (milk, eggs, fish, and others) and the levels of serum polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/F) concentrations of residents living near a municipal waste incinerator. All selected subjects were between 18 and 65 y...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(02)00058-0
更新日期：2003-03-01 00:00:00
abstract：:Although there is indirect evidence to suggest that persistent organochlorines might increase risk of hypertensive disorders of pregnancy, there are no epidemiologic studies directly addressing this question. In this cohort study, sampled from the Collaborative Perinatal Project, 1933 women had complete data on organo...
journal_title：Environmental research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.envres.2014.03.020
更新日期：2014-07-01 00:00:00
abstract：:Several epidemiological studies have shown that the farm environment impacts allergy protection mechanisms in children. These associations are not well understood, but it is thought that contact to microorganisms may mediate this effect. For example, heat-inactivated Listeria (L.) monocytogenes have been successfully ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2008.02.007
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Silver nanoparticles (Ag-NPs) are among the most commonly used nanomaterials and may be exposed to human and ecosystem. Prior in vitro study showed that Ag-NPs compromised neurodevelopment of PC12 cells. This study aims to investigate the effect of prenatal exposure to Ag-NPs on spatial cognition and hippoca...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.01.022
更新日期：2015-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.03.040
更新日期：2019-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109221
更新日期：2020-04-01 00:00:00
abstract：:The objective of this study was to determine mean blood lead levels and prevalence of elevated blood lead levels among 1- to 5-year-old children in Wuxi City, China. By use of a representative cross-sectional survey that included measurements of capillary blood lead, 1117 children aged 1-5 years were examined from Oct...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2001.4281
更新日期：2001-09-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109477
更新日期：2020-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.02.029
更新日期：2019-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.07.009
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:To study pregnancy outcome including development of childhood cancer in areas within Sweden with the highest radioactive fallout after the Chernobyl accident in 1986. METHODS:Various Swedish health registries were used in order to identify all pregnancies and their outcome in Sweden according to the measured...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1994.1070
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Bone lead measured via x-ray fluorescence (XRF) has been used for decades in health studies. A portable XRF device for bone lead measurement is gaining in popularity for its ease of use and shorter measurement times. Previous XRF devices have measured different bone types in order to sample both cortical and...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.02.031
更新日期：2019-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.01.008
更新日期：2011-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.03.008
更新日期：2010-07-01 00:00:00
abstract：:Closing the gap between carbon emissions and economic development is one of the solutions for reaching the sustainable development goals (SDGs). The role of renewable energy in rebalancing environmental and economic conditions is becoming a significant subject of some debates in the current discussion circles. Hence, ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109567
更新日期：2020-07-01 00:00:00
abstract：:We analyzed the exogenous mineral particle concentration, size, type, and distribution for particles larger than 0.1 micron in the left lungs of 10 long-term male cigarette smokers. The mean number of particles found was 465 +/- 295 X 10(6)/g dry lung, of which 80% were kaolinite, micas, feldspars, free silica, and ta...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80013-0
更新日期：1987-02-01 00:00:00
abstract：:Benzo[a]pyrene (BaP) is a useful indicator of exposure to polycyclic aromatic hydrocarbons (PAHs), airborne carcinogenic compounds. Radioimmunoassay was used to test for plasma BaP differences in 61 subjects divided into three groups based on geographic-demographic locale: urban-industrial, urban-residential, and oute...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90196-2
更新日期：1983-10-01 00:00:00
abstract：:Despite the ubiquity of microplastics (MPs) in aquatic environments and their proven ability to carry a wide variety of chemicals, very little is known about the impacts of virgin or contaminant-loaded MPs on organisms. The primary aim of this study was to investigate the impacts of virgin or phenanthrene (Phe)-loaded...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.07.024
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Previous studies have found that human mobility restrictions could not only prevent the spread of COVID-19, but also improve the air quality because of the reduction of industrial production, transportation and traffic. It is noteworthy that air quality is also closely related to the risk of COVID-19 infecti...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109911
更新日期：2020-10-01 00:00:00
abstract：:Some studies have reported an association between overexposure to selenium and risk of amyotrophic lateral sclerosis (ALS), a rare degenerative disease of motor neurons. From 1986 through 2015, we followed a cohort in Northern Italy that had been inadvertently consuming tap water with unusually high concentrations of ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108742
更新日期：2019-12-01 00:00:00
