Abstract:
:Acute transverse myelitis (ATM) is an inflammatory demyelinating disorder that affects the spinal cord focally resulting in motor sensory and autonomic dysfunction. Establishing the diagnosis of ATM is not as difficult as determining the possible etiology. There is a difference in the perception of ATM seen in the West as compared to developing countries. In the West multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous system. An attack of ATM may be the beginning of MS. However, this may not be the case in developing countries where MS is uncommon. Most often transverse myelitis is monophasic and at best represents a site-restricted form of acute disseminated encephalomyelitis (ADEM). Traditionally the combination of optic neuritis and ATM, occurring as a monophasic illness would have been called as neuromyelitis optica (NMO). Changing concepts in the definition of NMO and the discovery of a biomarker, neuromyelitis optica immunoglobulin (NMO_IgG), has changed the way relapsing autoimmune disorders are being perceived currently. A variety of idiopathic inflammatory disorders such as Japanese form of optic spinal MS, recurrent myelitis, and recurrent optic neuritis have been brought under the umbrella of neuromyelitis spectrum disorders because of the association with NMO-IgG. Complete transverse myelitis accompanied by longitudinally extensive transverse myelitis which is seronegative for this biomarker has also been reported from several countries including Japan, Australia, and India. Thus, ATM is a heterogeneous disorder with a varied clinical spectrum, etiology, and outcome.
journal_name
Neurol Indiajournal_title
Neurology Indiaauthors
Pandit Ldoi
10.4103/0028-3886.51278subject
Has Abstractpub_date
2009-03-01 00:00:00pages
126-33issue
2eissn
0028-3886issn
1998-4022pii
ni_2009_57_2_126_51278journal_volume
57pub_type
杂志文章,评审相关文献
NEUROLOGY INDIA文献大全abstract::Cervical split cord malformations are extremely rare with less than 75 cases reported in the literature worldwide. The widely different terminologies used to describe the same pathoanatomy make the documentation of all reported cases a difficult task. We conducted a systematic review of 71 cases documented over 38 rep...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.299132
更新日期:2020-09-01 00:00:00
abstract::Moyamoya disease, Japanese for 'puff of smoke', is a rare disease that presents most commonly with recurrent TIAs (transient ischemic attacks) / stroke in childhood. Ischemic symptoms in patients with moyamoya disease are usually due to hemodynamically-mediated perfusion failure. Identification of abnormal tissue perf...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::The advancements in the field of science in the past fifty years have highlighted the need to integrate all fields of human endeavours and have emphasised interdependency of various disciplines. The separation of humanities, therefore, from neurosciences is a preposterous practical joke on all thinking men. With the h...
journal_title:Neurology India
pub_type:
doi:
更新日期:1999-03-01 00:00:00
abstract::Parasitic twin is a rare occurrence, with rachispagus being the rarest. The surgical approach and timing are not standardized. We describe the management of two cases of rachispagus and review the sparse literature on this entity. Both cases were operated early because of the social burden on the family as well as dif...
journal_title:Neurology India
pub_type:
doi:10.4103/0028-3886.304090
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:To study the dynamic changes of pituitary hormones in traumatic brain injury (TBI) and to correlate the severity and neurological outcome. PATIENTS AND METHODS:Dynamic changes in the pituitary hormones were evaluated in 164 patients with TBI on day-1, day-7, day-14, day-21, and day-28 post injury. Admission ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.136922
更新日期:2014-05-01 00:00:00
abstract::Pituitary tumors may well be the most common brain tumors with a mean incidence of 16.7%. Even small tumors become symptomatic when they arise from functioning cells and produce devastating effects on the body. The nonfunctioning tumors may become quite large before producing symptoms due to raised intracranial pressu...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.287673
更新日期:2020-05-01 00:00:00
abstract::Neuronal migration disorders are an important differential diagnosis to be considered in the evaluation of intractable epilepsy. Though the underlying causative factors which govern their development are many and varied, genetic factors have been found to be contributory in a few forms of these disorders. An X-linked ...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::The exact diagnosis of demyelinating diseases is an enigma even in the best neurological centres. In the present study, the potential role of differential CSF proteins has been critically evaluated in differentiating multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM). Cellulose acetate electrophor...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:In this prospective study conducted over 2 years, 300 nonconsecutive cases of autosomal recessive limb girdle muscular dystrophies (AR-LGMD) were characterized, based on phenotypic features, biochemical findings, electrophysiological studies, muscle immunohistochemistry (IHC), and western blot (WB) analysis. ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.162048
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Asymptomatic carotid artery stenosis (ACAS) is a marker for cerebrovascular disease, coronary atherosclerosis, and death. AIM:To investigate the prevalence of ACAS in the Indian population, and to correlate ACAS with other vascular risk factors. MATERIALS AND METHODS:We prospectively recruited 1500 individ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/neuroindia.NI_523_16
更新日期:2017-03-01 00:00:00
abstract::The description of coma and coma arousal therapy in Caraka Saṁhitā is described in sṁtra 24, verses 42-53. It describes the definition of coma, differential diagnosis of coma from other disorders of consciousness, signs of coma, etiology of coma, coma arousal therapy, and emergence from coma. The similarities and diff...
journal_title:Neurology India
pub_type: 历史文章,杂志文章
doi:10.4103/neuroindia.NI_1110_16
更新日期:2017-03-01 00:00:00
abstract::The Achanta Lakshmipathi Neurosurgical Center (ALNC) and Post Graduate Institute of Neurological Surgery is a private teaching neurosurgical institution located in the VHS (Voluntary Health Services) Hospital Chennai. It has been a leader and trendsetter among the private academic neurosurgical training institutions, ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.257984
更新日期:2019-03-01 00:00:00
abstract::We present an unusual case of primary diffuse craniospinal leptomeningeal gliomatosis (PGDL), who was initially diagnosed on the basis of imaging, laboratory findings, and cranial meningeal biopsy as tuberculous meningitis and showed clinical deterioration while on anti-tuberculous treatment for 2 months. The patient ...
journal_title:Neurology India
pub_type:
doi:10.4103/0028-3886.217995
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND AIMS:To translate and test the reliability and validity of the Multiple Sclerosis Quality of Life Questionnaire (MSQoL-54) in Iranian MS patients. SETTING AND DESIGN:Using a standard "forward-backward" translation, cognitive debriefing and cultural adaptation procedure, the English version of the MSQoL-...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.33316
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Craniovertebral junction (CVJ) abnormalities, such as atlantoaxial dislocation (AAD) with or without basilar invagination (BI), with or without associated Chiari malformation (CM), may cause a high cervical myelopathy. Occasionally, mechanical factors such as inadequate canal decompression, torticollis, and/...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.193781
更新日期:2016-11-01 00:00:00
abstract::Hirayama disease (HD)/cervical flexion-induced myelopathy (CFIM) is a lower motor neuron disease conventionally affecting a single upper extremity. We describe three men progressing after a long stable period to develop severe spastic paraparesis and bladder disturbances as a protracted implication of HD. The age at o...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.236966
更新日期:2018-07-01 00:00:00
abstract::Chronic subdural haematoma (SDH) complicating chronic idiopathic thrombocytopenic purpura (ITP), in an adult is extremely rare. There are only four such case reports available in the literature and all these patients had surgical evacuation of the haematoma. We report an elderly female with chronic ITP presenting with...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::An adult male presenting with acute onset opsoclonus, myoclonus and cerebellar ataxia is being reported. Patient had myoclonus involving limbs and palate. There are only a few reported cases associated with palatal myoclonus. Patient showed gradual spontaneous recovery. Possibility of underlying malignancy was exclude...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract:Objective and Aims:To study hormonal axis (HA) dysfunction pre-operatively and at three months after surgery in patients with large (>3 cms) (Hardy's grade C) and giant (>4 cms) nonfunctioning pituitary adenomas (NFPA). Methods:One hundred thirty nine patients operated between 2006 and 2017, with 3 months post-operati...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.287670
更新日期:2020-05-01 00:00:00
abstract::There are more than 10 million persons with epilepsy (PWE) in India. Despite availability of antiepileptic drugs (AEDs), there is a large treatment gap varying from 50 to 70% among PWE. For treatable epilepsy, this gap can be attributed to poor education, poverty, cultural beliefs, stigma, and poor healthcare infrastr...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/neuroindia.NI_1070_16
更新日期:2017-01-01 00:00:00
abstract::78 autopsy proven cases of infective endocarditis (IE) seen during 1983 to 1995 were retrospectively reviewed. The brain was available for examination in 44 cases. In the remaining cases, brain was not examined because examination of it was not requested due to lack of neurological findings. Brain lesions were observe...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract::Botulinum toxin has gained immense popularity since its introduction for therapeutic use. It is used in a variety of movement disorders like hemi-facial spasm, focal dystonias like blepharospasm, cervical dystonia, oromandibular dystonia, limb dystonias. It is also being used in patients with tremors, tics and for a v...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.226441
更新日期:2018-03-01 00:00:00
abstract::Primary intraventricular haemorrhage secondary to thrombolytic therapy has not been reported. A 55 years male who received i.v. streptokinase (STK) followed by heparinization for an acute myocardial infraction developed an extensive primary intraventricular haemorrhage from which he made an uneventful recovery over th...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Over the last 10 years from 1982-1992, we have diagnosed 29 cases of multiple sclerosis at our centre. In this hospital based retrospective study, 22 cases were definite (including 4 cases of Neuromyelitis optica) and the remaining 7 were probable cases of multiple sclerosis according to Poser's criteria (Poser et al ...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract:Objective:To investigate the application value of using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with extended Tofts linear model for relapsing-remitting multiple sclerosis (RRMS) and its correlation with expanded disability status scale (EDSS) scores and disease duration. Materials and Methods:T...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.232324
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Malignant middle cerebral artery (MCA) infarction is associated with high mortality and morbidity. Decompressive hemicraniectomy (DH) reduces mortality significantly but evidence for long-term functional benefit is sparse and contradictory. MATERIALS AND METHODS:A total of 60 patients with malignant MCA inf...
journal_title:Neurology India
pub_type: 临床试验,杂志文章
doi:10.4103/0028-3886.128273
更新日期:2014-01-01 00:00:00
abstract:Background:Vagal nerve stimulation (VNS) is a form of neuromodulation for patients with drug-refractory epilepsy (DRE), in whom extensive preoperative evaluation fails to localize the epileptogenic zone. VNS is often compared to Corpus callosotomy (CC) in terms of both indications and efficacy. However, VNS represents ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.302458
更新日期:2020-11-01 00:00:00
abstract::The Madras Medical College and its affiliated Government General Hospital, Chennai, are among the oldest medical institutions in India. The Madras Institute of Neurology (MIN) was the second neurosciences department to be started in India. The MIN has trained several batches of illustrious neurologists and neurosurgeo...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.170058
更新日期:2015-11-01 00:00:00
abstract::A histopathologically proven case of cerebral toxoplasmosis in a young HIV positive patient has been presented. The clinical problems in management are highlighted. ...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Chemical asymmetries in normal human brain were studied using the non-invasive technique of volume localized proton magnetic resonance spectroscopy (MRS). The technique of STEAM was used to acquire water-suppressed proton spectra from 8 ml voxels placed in bilaterally symmetrical positions in the two hemispheres of th...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00