Role of preoperative imaging in the diagnosis of primary diffuse craniospinal leptomeningeal gliomatosis.

Abstract:

:We present an unusual case of primary diffuse craniospinal leptomeningeal gliomatosis (PGDL), who was initially diagnosed on the basis of imaging, laboratory findings, and cranial meningeal biopsy as tuberculous meningitis and showed clinical deterioration while on anti-tuberculous treatment for 2 months. The patient was subsequently correctly diagnosed on diffusion weighted and post-contrast T1-weighted imaging of the craniospinal axis along with whole body imaging. The radiological findings were confirmed on histopathology and immunohistochemistry performed from the previous block as well as biopsy from the nodular mass in the lumbosacral meninges. We conclude that peroperative imaging may help in pinpointing the correct diagnosis and assist in guiding the surgeon to the site of biopsy.

journal_name

Neurol India

journal_title

Neurology India

authors

Vishal J,Patir R,Ahlawat S,Gupta RK

doi

10.4103/0028-3886.217995

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

1330-1332

issue

6

eissn

0028-3886

issn

1998-4022

pii

ni_2017_65_6_1330_217995

journal_volume

65

pub_type

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    authors: Kayal AK,Goswami M,Das M,Paul B

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    abstract:BACKGROUND:Cryptococcal meningitis is a common opportunistic infection in Human Immunodeficiency Virus (HIV)-infected individuals. There is little information specifically addressing cryptococcal meningitis in HIV-infected patients from North India. AIMS:To determine clinical presentation, hospital course, response to...

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    authors: Soni N,Srindharan K,Kumar S,Bhaisora KS,Kalita J,Mehrotra A,Mishra P

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