Massive pontine hemorrhagic transformation associated with an anticoagulant for basilar artery occlusion.

Abstract:

:Symptomatic hemorrhagic transformation is common in supratentorial and cerebellar infarction, but is rare in brainstem infarction. It is seldom reported in basilar artery occlusion. Although early arterial recanalization by thrombolytic agent has became the new trend of treatment, for some neurologists anticoagulant is still a conventional alternative treatment of basilar artery occlusion, especially in longer-existing ischemic deficits. We report a case of massive pontine hemorrhage associated with enoxaparin (low-molecular-weight heparin) treatment for basilar artery occlusion. On the basis of the clinical information and neuroimaging, an embolism was the most likely cause of stroke. The case presented herein adds massive pontine hemorrhagic transformation to the list of possible complications of anticoagulants for basilar artery occlusion. Apart from no evidence-based benefit in treatment of basilar artery occlusion, anticoagulant may contribute to devastating hemorrhagic transformation.

journal_name

Neurol India

journal_title

Neurology India

authors

Hsiao MC,Lee JD,Lee M,Weng HH

doi

10.4103/0028-3886.28123

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

431-3

issue

4

eissn

0028-3886

issn

1998-4022

journal_volume

54

pub_type

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