Vagal Nerve Stimulation for Drug Refractory Epilepsy.

Abstract:

Background:Vagal nerve stimulation (VNS) is a form of neuromodulation for patients with drug-refractory epilepsy (DRE), in whom extensive preoperative evaluation fails to localize the epileptogenic zone. VNS is often compared to Corpus callosotomy (CC) in terms of both indications and efficacy. However, VNS represents a less invasive and less morbid procedure compared to CC and is the preferred procedure in majority of patients with DRE. Objective:The aim of this study was to present the surgical technique and nuances involved in the implantation of vagal nerve stimulator. Procedure:A 16-year-old boy suffering from DRE, with bilateral seizure onset on evaluation, for 12 years, underwent left vagal nerve stimulator placement. The VNS device has a lead and a pulse generator, the lead has coils to be wrapped around the vagus nerve and the pulse generator is placed in a subcutaneous pocket in the infraclavicular region (demonstrated in the video). Results:The patient is relieved of the disabling drop attacks along with improved cognitive functions at 1 year follow up. Conclusions:In carefully selected patients, VNS is a safe and effective procedure to alleviate seizures, in cases otherwise morbidly affected due to drug refractory epilepsy.

journal_name

Neurol India

journal_title

Neurology India

authors

Chandra PS,Samala R,Agrawal M,Doddamani RS,Ramanujam B,Tripathi M

doi

10.4103/0028-3886.302458

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

S325-S327

issue

Supplement

eissn

0028-3886

issn

1998-4022

pii

ni_2020_68_8_325_302458

journal_volume

68

pub_type

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