Abstract:
Background:Due to the paucity of quick, cognitive screening tools available in India that are independent of cultural and educational influences, a 6-item paper and pencil test, covering areas of memory, executive functioning, attention, and visuospatial ability domains - the Neuropsychological Evaluation Screening Tool (NEST) was developed. Aim and Method:NEST was administered to 84 healthy controls to analyze, revise, and review items. In the second phase, 408 patients, above 16 years of age, with their educational level ranging from being illiterate to having greater than 25 years of education, with various neurological and psychiatric conditions were independently administered NEST, Hindi Mental State Examination (HMSE), and a detailed cognitive evaluation using PGI Memory Scale (PGIMS). Results:Using receiver operating characteristics analysis for 341 patients, ≥3 was identified as the optimum cut-off for NEST. NEST could correctly classify 87.9% of the patients with an impaired vs. an intact cognition. The diagnostic characteristics of NEST with PGIMS were sensitivity (95% CI): 94.78% (91.1, 97.3); specificity (95% CI): 60.31% (51.3, 68.7); positive predictive value (95% CI): 80.74% (78.1, 93.0); and negative predictive value (95% CI): 86.81% (75.6, 85.3). NEST had an 82.5% agreement (95% CI: 78.1, 86.2) with PGIMS. On the other hand, the diagnostic characteristics of HMSE with PGIMS were sensitivity (95% CI): 73.79% (67.5, 79.3); specificity (95% CI): 82.44% (74.8, 88.5); positive predictive value (95% CI): 88.02% (82.5, 92.2); and negative predictive value (95% CI): 64.3% (56.5, 71.5). HMSE had a 76.95% (95% CI: 72.2, 81.1) agreement with PGIMS. Conclusions:NEST has better sensitivity compared to HMSE for detecting cognitive impairment when compared to a detailed evaluation at all educational levels.
journal_name
Neurol Indiajournal_title
Neurology Indiaauthors
Chopra S,Kaur H,Pandey RM,Nehra Adoi
10.4103/0028-3886.227304subject
Has Abstractpub_date
2018-03-01 00:00:00pages
391-399issue
2eissn
0028-3886issn
1998-4022pii
ni_2018_66_2_391_227304journal_volume
66pub_type
杂志文章相关文献
NEUROLOGY INDIA文献大全abstract:BACKGROUND:Numerous studies have investigated the associations of brain or spinal cord MRI with the risk of developing Multiple Sclerosis (MS) in people with Clinically Isolated Syndrome (CIS), however, the findings are uncertain. Therefore, we performed a meta-analysis based on 24 publications to comprehensively evalu...
journal_title:Neurology India
pub_type: 杂志文章,meta分析
doi:10.4103/0028-3886.115058
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:While the clinical and immunocytochemical features of sarcoglycanopathies have been reported from India, genetic aspects have not been studied. There is large variation in the sarcoglycan mutations among the studied populations. AIM:To study the spectrum of mutations in sarcoglycan genes (SG). MATERIALS AN...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.55603
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to conduct a retrospective analysis of the clinical characteristics of 20 individuals with intramedullary cavernous angiomas (ICA) presented with serious pain complaints. This study was to investigate the efficacy of short- and long-term pain relief following surgical resection...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.141477
更新日期:2014-07-01 00:00:00
abstract::In the October of 1996, Lance Armstrong, celebrated cyclist and one of the greatest athletes the world has ever seen, at the age of 24, was diagnosed with metastatic testicular cancer with disease having already spread to his abdomen, lungs and brain. Lance underwent four cycles of chemotherapy, actually the pretty st...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.48794
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Comparative study of Class I drugs in central poststroke pain (CPSP) is lacking. OBJECTIVE:To evaluate the safety and efficacy of pregabalin and lamotrigine in patients with CPSP. SETTING:Tertiary care teaching referral hospital. METHODS:We included consecutive patients with CPSP having ≥50 mm score on Vi...
journal_title:Neurology India
pub_type: 杂志文章,随机对照试验
doi:10.4103/neuroindia.NI_45_16
更新日期:2017-05-01 00:00:00
abstract::Seventy cases of primary degenerative cerebellar ataxias in ethnic Bengalees from southern West Bengal, India, were studied by the authors. Of these, 50 cases were of the familial type (hereditary ataxias) encountered in 23 families and the remaining 20 were of sporadic onset. 18 cases (from 11 families) were of "prob...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract::The Department of Neurological Sciences at Christian Medical College (CMC), Vellore was the first department to start neurosurgical and neurological services in India. Jacob Chandy started the department in 1949 against several odds. He started a formal training program in neurosurgery in 1958, for the first time in I...
journal_title:Neurology India
pub_type: 历史文章,杂志文章
doi:10.4103/0028-3886.177625
更新日期:2016-03-01 00:00:00
abstract:Background:Spinal dural arteriovenous fistula (SDAVF) is a known cause of progressive myelopathy which can be treated either by surgery or embolization. Indocyanine green angiography videoangiography (ICG-VA) during surgery can locate the exact location of AV shunting. Objective:To determine the clinical outcome follo...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.279705
更新日期:2020-01-01 00:00:00
abstract::The Kluver-Bucy syndrome (KBS) is a neurobehavioral syndrome and can be seen in association with a variety of neurological disorders. Case records of 6 patients with KBS seen during a period of 5 years in a university hospital were reviewed. During the study period 6 patients with KBS, aged between 4 and 14 years, wer...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::Although the conventional hematoxylin and eosin (H and E) staining is vital for the histological diagnosis of lesions, the role of immunohistochemistry (IHC) is undeniable in surgical pathology. Morphology, which looks more or less similar on H and E staining, can be further differentiated by merely doing IHC. This, i...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.181547
更新日期:2016-05-01 00:00:00
abstract::The present report highlights an unusual presentation of vitamin B12 deficiency--recurrent seizures in a 26-year-old man. His symptoms responded to parenteral vitamin B12 therapy. The relevant literature is reviewed. ...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract::The Madras Medical College and its affiliated Government General Hospital, Chennai, are among the oldest medical institutions in India. The Madras Institute of Neurology (MIN) was the second neurosciences department to be started in India. The MIN has trained several batches of illustrious neurologists and neurosurgeo...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.170058
更新日期:2015-11-01 00:00:00
abstract::We report three patients with pyomyositis due to Staphylococcus aureus. Magnetic resonance imaging aided in the accurate diagnosis of the infection and of the extent of involvement. Incision, drainage and antibiotic therapy eradicated the infection in all the patients. We suggest clinical or subclinical bacteraemic se...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::Enterogenous cyst is extremely rare in the supratentorial compartment. Two adult patients with histologically variefied supratentorial entrogenous cyst are described. Light microscopy and immunohistochemistry examination revealed the endodermal origin of the cyst. Enterogenous cyst should be considered in the differen...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.72200
更新日期:2010-09-01 00:00:00
abstract::Giant cell arteritis (GCA), the most common form of systemic granulomatous vasculitis in adults, preferentially involves large and medium-sized arteries. Scalp necrosis is a rare complication and can be the presenting feature. This report presents two patients of GCA with severe scalp necrosis as the presenting sympto...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.48817
更新日期:2009-01-01 00:00:00
abstract::Granulomatous amoebic encephalitis (GAE) caused by certain species belonging to the genus Acanthamoeba, Balamuthia, or Naegleria presents as a subacute or chronic illness. Amoebic encephalitis caused by Acanthamoeba is seen more often in immunosuppressed individuals. Thus, it may often be associated with human immunod...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.173662
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Limb girdle muscular dystrophy (LGMD) is a phenotypic expression of a heterogeneous group of diseases and sarcoglycanopathy is one of the causes of LGMD. There is only one study on sarcoglycanopathies in the Indian literature. No data is available from northern India. MATERIALS AND METHODS:All cases of musc...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Restless leg syndrome (RLS) has negative effects on the quality of life of the patients. Epidemiological studies on RLS are limited. AIM:To determine the prevalence of RLS among people aged 40 years and above in Orhangazi district of Bursa, Turkey. MATERIALS AND METHODS:The study was carried out between 20...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.59467
更新日期:2009-11-01 00:00:00
abstract::Intracranial schwannoma is a kind of benign intracranial tumors, derived from neuron myelin sheath, growing slowly and curable. Olfactory schwannoma is an exceedingly rare kind of schwannoma, whose origin is still uncovered. Although several theories have been put up for pathogenesis of olfactory schwannoma, till now,...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:10.4103/0028-3886.141289
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Diagnosis of myasthenia gravis is difficult, especially when the disease is restricted to ocular muscles. It is a well-known observation that myasthenic ptosis improves with cold and based on this, the ice pack test has been used as a tool in its differential diagnosis. The aim of the study is to investigate...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.193780
更新日期:2016-11-01 00:00:00
abstract::This report describes a case of acute steroid-induced myopathy following a single dose of oral prednisolone. A 55-year-old man presented with an acute exacerbation of chronic obstructive pulmonary disease, which was treated with prednisolone 40 mg daily in addition to bronchodilators. He developed features of myopathy...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Asymptomatic carotid artery stenosis (ACAS) is a marker for cerebrovascular disease, coronary atherosclerosis, and death. AIM:To investigate the prevalence of ACAS in the Indian population, and to correlate ACAS with other vascular risk factors. MATERIALS AND METHODS:We prospectively recruited 1500 individ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/neuroindia.NI_523_16
更新日期:2017-03-01 00:00:00
abstract::There had been considerable debate regarding the surgical outcome of neuro-orthopaedic syndromes (NOS) and neurological syndromes in cases of split cord malformation (SCM). On retrospective analysis of 19 cases of SCM, thirteen were grouped under (Pang) type I and 6 in type II. Their age ranged from 1 month to 9 years...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::Primary intraventricular haemorrhage secondary to thrombolytic therapy has not been reported. A 55 years male who received i.v. streptokinase (STK) followed by heparinization for an acute myocardial infraction developed an extensive primary intraventricular haemorrhage from which he made an uneventful recovery over th...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Cerebral amyloid angiopathy (CAA) is well known to present with lobar intracerebral hemorrhage, dementia or transient neurological events. White matter changes with CAA have only been recently described and can be seen with either sporadic or familial CAA. We present a 50-year-old man with rapidly progressive dementia...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::Surgical options for suprasellar arachnoid cyst are cystoperitoneal shunt, craniotomy fenestration and endoscopic fenestration. Endoscopic management has been found to be safe and effective. We report our experience with endoscopic management in 12 (male five, female seven; age range 8 months to 42 years) patients wit...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.63772
更新日期:2010-03-01 00:00:00
abstract::Chordoid glioma is a rare low-grade tumor located in the third ventricle-hypothalamic region. Since its first report, 37 cases have been described in the literature. We report on an additional case that we considered significant because of its incidental detection and its uneventful surgical removal. ...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.33301
更新日期:2007-10-01 00:00:00
abstract::In this paper we report an 18 year old woman with an intradural extramedullary tuberculoma mimicking en plaque meningioma located in the thoracic region. The patient was operated via thoracic laminoplasty and tumor was totally resected. On the follow-up examination the magnetic resonance imaging demonstrated the total...
journal_title:Neurology India
pub_type: 杂志文章
doi:10.4103/0028-3886.51300
更新日期:2009-03-01 00:00:00
abstract::Two cases of haemorrhage during cranial computed tomography (CT) occurring during the enhancement phase of CT examination immediately after the administration of intravenous contrast medium are reported. In both cases, the preceding unenhanced scansshowed evidence of haemorrhage. The risk of aneurysmal rupture as a re...
journal_title:Neurology India
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::Predicting the outcome of critically ill patients admitted to intensive care units (ICU) has undergone considerable evolution over the last two decades. Various general purpose severity-of-illness scoring systems, Acute Physiology and Chronic Health Evaluation score (APACHE II, APACHE III), Mortality Predicting Model ...
journal_title:Neurology India
pub_type: 杂志文章,评审
doi:
更新日期:2001-06-01 00:00:00