Abstract:
PURPOSE:To evaluate feasibility and added value of dual-energy computed tomography (CT) in diagnosis of pulmonary embolism (PE). MATERIALS AND METHODS:This institutional animal experimental committee-approved study was performed in accordance with animal care guidelines. Eight New Zealand rabbits underwent standard unenhanced and contrast material-enhanced dual-source CT. Gelatin sponge particles were injected into the pulmonary artery, and rabbits underwent contrast-enhanced dual-source CT pulmonary angiography, from which blood-flow (BF) and fusion images were created. Immediately after dual-source CT, rabbits were sacrificed, their lungs were removed and fixed in 10% formalin, and detailed pathologic determination of location and number of lung lobes with PE was performed. Two rabbits were excluded: One died during the procedure. In the other, the catheter tip was retained in the left inferior pulmonary artery. This caused marked postembolization CT image artifacts in adjacent regions. Six rabbits were included in final analysis. Two radiologists without knowledge of pathologic results evaluated five pulmonary lobes in each rabbit and recorded whether PE was present. Pathologic results served as the reference standard. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the techniques were calculated. Weighted kappa values were calculated to evaluate agreement between modalities. RESULTS:Pathologic analysis revealed PE in 18 of 30 pulmonary lobes. Conventional CT angiography was used to correctly identify PE in 12 lobes and absence of emboli in 18 lobes, which corresponded to sensitivity, specificity, PPV, and NPV of 67%, 100%, 100%, and 67%, respectively. A kappa value of 0.65 indicated good correlation with pathologic findings. On BF images, segments with an embolic region showed low perfusion compared with segments with a normal pulmonary region. BF images and fused images correctly showed PE in 16 of 18 pulmonary lobes and absence of emboli in 11 of 12 lobes, which corresponded to sensitivity, specificity, PPV, and NPV of 89%, 92%, 94%, and 85%, respectively, in detection of PE. A kappa value of 0.80 indicated good correlation with pathologic findings. CONCLUSION:Dual-source CT can depict normal and abnormal blood perfusion distribution in a rabbit's lung. Abnormal pulmonary blood distribution, as shown at dual-source CT, improves detection of acute PE in rabbits.
journal_name
Radiologyjournal_title
Radiologyauthors
Zhang LJ,Zhao YE,Wu SY,Yeh BM,Zhou CS,Hu XB,Hu QJ,Lu GMdoi
10.1148/radiol.2521081682subject
Has Abstractpub_date
2009-07-01 00:00:00pages
61-70issue
1eissn
0033-8419issn
1527-1315pii
252/1/61journal_volume
252pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::All screening radiographs of the chest and other medical records of 107 patients with histologically proved lung cancer in a fixed population were reviewed to assess the efficacy of biennial chest radiography in detecting lung cancer. Radiographic abnormalities caused by tumors were initially detected in 58 patients (...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.148.2.6306720
更新日期:1983-08-01 00:00:00
abstract::The preangiographic diagnosis of cerebral dural arteriovenous fistula (DAVF) can be difficult. The magnetic resonance (MR) images of 12 patients with angiographically proved DAVF were evaluated to characterize the appearance of these lesions and to identify those patients at increased risk for complications. Patients ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.175.1.2315480
更新日期:1990-04-01 00:00:00
abstract:PURPOSE:To retrospectively evaluate the prevalence of focal fluorodeoxyglucose (FDG) uptake by the thyroid gland on combined positron emission tomographic (PET) and computed tomographic (CT) scans in patients undergoing staging of newly diagnosed non-small cell lung cancer (NSCLC). MATERIALS AND METHODS:Institutional ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2361041007
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:To determine the effects of the Valsalva maneuver on intraluminal colon pressure during air enema studies. MATERIALS AND METHODS:Air enema studies were performed in four adult volunteers, and intraluminal colon pressure measurements were recorded with a high-speed electronic strip chart and aneroid gauge metho...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.202.3.9051040
更新日期:1997-03-01 00:00:00
abstract::The diagnosis of seminal vesicle invasion by prostatic carcinoma is based on observation of foci of relatively decreased signal intensity on T2-weighted magnetic resonance (MR) images. Similar findings were observed in the absence of tumor invasion in nine patients who had recently undergone prostatic needle biopsy. N...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.185.2.1410340
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:To test a neural network in differentiation of benign from malignant solitary pulmonary nodules. MATERIALS AND METHODS:Neural networks were trained and tested on the characteristics of 318 nodules. Predictive accuracy of the network was judged for calibration and discrimination. Network results were compared w...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.196.3.7644650
更新日期:1995-09-01 00:00:00
abstract::Purpose To evaluate the performance of three imaging methods (radiography, dual-energy x-ray absorptiometry [DXA], and quantitative computed tomography [CT]) and that of a numerical analysis with finite element modeling (FEM) in the prediction of failure load of the proximal femur and to identify the best densitometri...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016142796
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To compare quantified measurements with color Doppler ultrasonography (US) with those obtained with conventional duplex US in the differential diagnosis of suspect lesions in the breast. MATERIALS AND METHODS:A computer-assisted protocol was used to calculate the color pixel density (CPD) and the mean color va...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.192.3.8058950
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:To determine the effect of the interpretation of plain chest radiographs on the time to definitive diagnosis of aortic dissection. MATERIALS AND METHODS:The authors evaluated chest radiographs from 75 patients in whom chest radiography was performed before aortic dissection was diagnosed. The radiographs and a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.193.3.7972830
更新日期:1994-12-01 00:00:00
abstract:PURPOSE:To assess diagnostic accuracy of preoperatively performed magnetic resonance (MR) imaging for detection of tumor extent in a large patient population with histopathologically proved retinoblastoma. MATERIALS AND METHODS:Local ethics committee approval and informed consent were not required for retrospective re...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2351031301
更新日期:2005-04-01 00:00:00
abstract::Fifty-six cases of spondylolysis were encountered in 1500 lumbar spine reports reviewed. The frequency of detecting isthmus defects on anteroposterior (AP), lateral, 45-degree right and left oblique, 30-degree up-angled AP, and collimated lateral views was determined. The collimated lateral view showed the largest num...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.153.3.6494460
更新日期:1984-12-01 00:00:00
abstract::The authors have occasionally observed nodular areas abutting the lateral diaphragmatic surface and extending into the posterior pararenal space on computed tomographic (CT) scans. Review of the anatomy literature revealed that this finding represents inferolateral extension of the lateral arcuate ligaments, which ref...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.185.1.1523290
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:To determine whether the computed tomographic (CT) appearances of multiple pulmonary nodules in patients with acquired immunodeficiency syndrome (AIDS) can help differentiate the potential infectious and neoplastic causes. MATERIALS AND METHODS:The thoracic CT scans obtained in 60 patients with AIDS and multip...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.2.r00fe22427
更新日期:2000-02-01 00:00:00
abstract::In two pathologically documented cases of renal cell carcinoma, the appearance of the tumors at magnetic resonance (MR) imaging was markedly hypointense relative to normal renal parenchyma on both T1- and T2-weighted spin-echo images. Pathologic examination of both tumors revealed diffuse iron scattered throughout the...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.177.2.2217790
更新日期:1990-11-01 00:00:00
abstract::Radiolabeling of Ivalon (polyvinyl alcohol sponge) particles permits localization of injected particles during embolization through the use of a portable gamma camera and provides a means to prevent potentially fatal complications such as pulmonary embolization. A more efficient technique of labeling Ivalon particles ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.177.2.2217800
更新日期:1990-11-01 00:00:00
abstract::To investigate spatial resolution requirements for digitized portal images in radiation therapy, observer performance tests were performed. One hundred twenty portal images were digitized with sampling frequencies of 0.700, 0.350, and 0.175 mm for observation. Receiver operating characteristic analysis was used to det...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.183.2.1561370
更新日期:1992-05-01 00:00:00
abstract::Twenty-eight patients with intra-abdominal mesenchymal sarcomas were examined with gray scale ultrasonography. Masses were present in the mesentery, abdominal hollow viscera, liver, and retroperitoneal areas. Four different ultrasonic patterns were observed in the extra hepatic abdominal masses: (a) hyperechoic masses...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/128.1.193
更新日期:1978-07-01 00:00:00
abstract::Dedifferentiated chondrosarcomas, unlike ordinary chondrosarcomas, are highly aggressive tumors that frequently metastasize. The lesion is characterized by a lytic intraosseous or extraosseous soft-tissue mass that is devoid of the calcifications that are usually associated with a chondroid tumor. We describe the radi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.161.2.3763920
更新日期:1986-11-01 00:00:00
abstract:PURPOSE:To assess the feasibility of automatic needle-guide tracking by using a real-time phase-only cross correlation ( POCC phase-only cross correlation ) algorithm-based sequence for transrectal 3-T in-bore magnetic resonance (MR)-guided prostate biopsies. MATERIALS AND METHODS:This study was approved by the ethics...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.14132067
更新日期:2014-12-01 00:00:00
abstract::Lymphangiomas are rare, benign tumors which may become opacified during lymphography and may be confused with malignant lymph node disease. A case is reported in which lymphography showed focal collections of contrast material retained for several days in dilated lymphatic spaces which initially simulated metastatic d...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/115.2.355
更新日期:1975-05-01 00:00:00
abstract:PURPOSE:To study tissue platinum concentrations and the correlation between tissue and plasma platinum concentrations after negative-balance isolated pelvic perfusion (NIPP) in a porcine model. MATERIALS AND METHODS:All animal experiments were conducted according to the University Guidelines for Animal Care and Experi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11102453
更新日期:2012-02-01 00:00:00
abstract::Background Glomerulonephritis refers to renal diseases characterized by glomerular and tubulointerstitial fibrosis. Multifrequency US time-harmonic elastography enables the noninvasive quantification of tissue elasticity. Purpose To assess the diagnostic performance of US time-harmonic elastography for the early detec...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2019182574
更新日期:2019-09-01 00:00:00
abstract::One hundred thirty-three cervical spine radiographs of 50 patients with rheumatoid arthritis were examined. The patients were a representative random sample chosen from among 675 patients followed up for more than 10 years. The frequency of occurrence for each radiographic finding was correlated with the duration of r...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.165.1.3628760
更新日期:1987-10-01 00:00:00
abstract:PURPOSE:To determine the individual technical costs of general diagnostic radiographic, ultrasonographic (US), computed tomographic (CT), magnetic resonance (MR) imaging, and scintigraphic examinations and interventional radiology. MATERIALS AND METHODS:The Radiology Cost and Productivity Benchmarking Study method of ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.216.1.r00jl18269
更新日期:2000-07-01 00:00:00
abstract::Differences in magnetic resonance (MR) imaging signal-to-noise (S/N) performance between saddle-shaped and solenoidal coils have been postulated. Each coil shape is tied to a particular magnetic field configuration, so that they are not typically interchangeable except in special situations. The solenoidal coil is pre...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.154.1.3964940
更新日期:1985-01-01 00:00:00
abstract::The authors examined 10 healthy male subjects with dynamic computed tomography to determine normal dynamic and expiratory findings. In both the supine and prone positions, the average increase in lung attenuation during exhalation was found to be significantly greater in dependent lung regions than in nondependent lun...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.186.1.8416550
更新日期:1993-01-01 00:00:00
abstract::Fifty cadaver ankles were examined with ankle tenography. The normal tenographic appearance of the peroneus longus and brevis, posterior tibial, flexor digitorum longus, flexor hallucis longus, anterior tibialis, extensor hallucis longus, and extensor digitorum longus tendons and sheaths are described and illustrated ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.151.3.6718710
更新日期:1984-06-01 00:00:00
abstract:PURPOSE:To report population-based utilization rates and their variability across and within populations, geographic areas, and different payment systems for diagnostic radiology and radiation oncology procedures. MATERIALS AND METHODS:Aggregated claims data were obtained from four sources for up to nine radiologic mo...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.200.1.8657910
更新日期:1996-07-01 00:00:00
abstract::High-resolution magnetic resonance (MR) images of the skin were acquired with a whole-body MR system at 1.5 T by adding a specific imaging module: A saddle-shaped surface gradient coil was connected in place of one of the gradient coils of the system, and a surface radio-frequency coil with a 1.5-cm radius was placed ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.176.2.2367660
更新日期:1990-08-01 00:00:00
abstract::A retrospective study of 160 pediatric subjects, aged 32-410 weeks after conception, was conducted to determine the normal developmental patterns of the human cerebellum by means of magnetic resonance (MR) imaging. On the basis of axial T2-weighted spin-echo images (repetition time, 3,000 msec; echo time, 120 msec), w...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.177.2.2217780
更新日期:1990-11-01 00:00:00