Abstract:
:The COVID-19 pandemic placed public health measures against infectious diseases at the core of global health challenges, especially in cities where more than half of the global population lives. SARS-CoV-2 is an exposure agent recently added to the network of exposures that comprise the human exposome, i.e. the totality of all environmental exposures throughout one's lifetime. At the same time, the application of measures to tackle SARS-CoV-2 transmission leads to changes in the exposome components and in characteristics of urban environments that define the urban exposome, a complementary concept to the human exposome, which focuses on monitoring urban health. This work highlights the use of a comprehensive systems-based approach of the exposome for better capturing the population-wide and individual-level variability in SARS-CoV-2 spread and its associated urban and individual exposures towards improved guidance and response. Population characteristics, the built environment and spatiotemporal features of city infrastructure, as well as individual characteristics/parameters, socioeconomic status, occupation and biological susceptibility need to be simultaneously considered when deploying non-pharmacological public health measures. Integrating individual and population characteristics, as well as urban-specific parameters is the prerequisite in urban exposome studies. Applications of the exposome approach in cities/towns could facilitate assessment of health disparities and better identification of vulnerable populations, as framed by multiple environmental, urban design and planning co-exposures. Exposome-based applications in epidemics control and response include the implementation of exposomic tools that have been quite mature in non-communicable disease research, ranging from biomonitoring and surveillance to sensors and modeling. Therefore, the exposome can be a novel tool in risk assessment and management during epidemics and other major public health events. This is a unique opportunity for the research community to exploit the exposome concept and its tools in upgrading and further developing site-specific public health measures in cities.
journal_name
Environ Intjournal_title
Environment internationalauthors
Andrianou XD,Pronk A,Galea KS,Stierum R,Loh M,Riccardo F,Pezzotti P,Makris KCdoi
10.1016/j.envint.2020.106246subject
Has Abstractpub_date
2021-01-01 00:00:00pages
106246eissn
0160-4120issn
1873-6750pii
S0160-4120(20)32201-7journal_volume
146pub_type
杂志文章,评审abstract:OBJECTIVE:Estimate the health risks and benefits of mode shifts from car to cycling and public transport in the metropolitan area of Barcelona, Spain. METHODS:We conducted a health impact assessment (HIA), creating 8 different scenarios on the replacement of short and long car trips, by public transport or/and bike. T...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2012.08.009
更新日期:2012-11-15 00:00:00
abstract::Treated wastewater (TWW) is increasingly used for agricultural irrigation, especially in arid and semi-arid regions. Carbamazepine is among the most frequently detected pharmaceuticals in TWW. Moreover, its uptake and accumulation have been demonstrated in crops irrigated with TWW. A previous controlled trial found th...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105951
更新日期:2020-10-01 00:00:00
abstract::Oil spills are serious environmental issues that potentially can cause adverse effects on marine ecosystems. In some marine areas, like the Baltic Sea, there is a large number of wrecks from the first half of the 20th century, and recent monitoring and field work have revealed release of oil from some of these wrecks....
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.02.037
更新日期:2019-05-01 00:00:00
abstract::The increase in cases of asthma and allergies has become an important health issue throughout the globe. Although these ailments were not common diseases a few short decades ago, they are now affecting a large part of the population in many regions. Exposure to environmental (both outdoor and indoor) pollutants may pa...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2013.05.007
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Exposure to pesticides has been linked to Parkinson's disease (PD), although associations between specific pesticides and PD have not been well studied. Residents of rural areas can be exposed through environmental drift and volatilization of agricultural pesticides. OBJECTIVES:Our aim was to investigate th...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.07.001
更新日期:2017-10-01 00:00:00
abstract::A variety of experimental and epidemiological studies lend support to the Developmental Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for mid- and long-term effects of early-life exposures remain unclear. Epigenetic alterations such as changes in DNA methylation, histone modificat...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2018.02.014
更新日期:2018-05-01 00:00:00
abstract::Settled house dust can be a source of human exposure to toxic polycyclic aromatic hydrocarbons (PAHs) through non-dietary ingestion and dermal contact. Information regarding the concentrations of various contaminants in house dust would be useful in estimating the risk associated with exposure to these compounds. This...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2008.03.008
更新日期:2008-10-01 00:00:00
abstract::Brominated flame retardants, including polybrominated diphenyl ethers (PBDEs) have been incorporated in numerous products to reduce flammability. Depending on their bromination, PBDEs are relatively persistent in the environment and have the potential to bioaccumulate through the food web. The present study was initia...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2007.07.003
更新日期:2008-01-01 00:00:00
abstract::Per- and polyfluoroalkyl substances (PFASs) are ubiquitous in the environment, making it inevitable for humans to be exposed to these pollutants. The exposure begins while in utero and continues in infancy, during the potentially most sensitive early stages of life. This review summarizes the current knowledge on pre-...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2020.106012
更新日期:2020-11-01 00:00:00
abstract::Landfills are reservoirs of antibiotics, heavy metals, disinfectants and other emerging contaminants, and they are closely associated with the increasing prevalence of antibiotic-resistance genes (ARGs). In this study, two classes of clinical use antibiotics, i.e., fluoroquinolones (FQs) and β-lactams (BLs), twelve su...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.02.002
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:We investigated the associations between daily sales of respiratory medication and air pollutants in the Brussels-Capital Region between 2005 and 2011. METHODS:We used over-dispersed Poisson Generalized Linear Models to regress daily individual reimbursement data of prescribed asthma and COPD medication fro...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.06.019
更新日期:2016-09-01 00:00:00
abstract::Mercury contamination in soil, water and air is associated with potential toxicity to humans and ecosystems. Industrial activities such as coal combustion have led to increased mercury (Hg) concentrations in different environmental media. This review critically evaluates recent developments in technological approaches...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2019.105281
更新日期:2020-01-01 00:00:00
abstract::Water quality scenarios around an offshore outfall off Kochi were simulated using MIKE21 water quality model, assuming a high Biochemical Oxygen Demand (BOD=50 mg l(-1)) effluent discharge. The discharge is introduced into the model through an outfall located at a distance of 6.8 km from the shore at a depth of 10 m. ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2005.08.007
更新日期:2006-02-01 00:00:00
abstract::Long-term air quality data with high temporal and spatial resolutions are needed to understand some important processes affecting the air quality and corresponding environmental and health effects. The annual and diurnal variations of each criteria pollutant including PM2.5 and PM10 (particulate matter with aerodynami...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2015.11.003
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Human are widely exposed to multiple metals, some of which have suspected reproductive toxicity, but no human studies have investigated the developmental effects of prenatal metal exposure. OBJECTIVES:We aimed to evaluate the associations between prenatal multiple metal exposure and reproductive development...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105900
更新日期:2020-10-01 00:00:00
abstract::Bisphenol-A (BPA) is one of the highest volume chemicals produced worldwide, with over 6billion pounds produced and over 100t released into the atmosphere each year. Recent extensive literature has raised concerns about its possible implication in the etiology of some human chronic diseases such as diabetes, obesity, ...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2013.12.007
更新日期:2014-03-01 00:00:00
abstract::The low Ebro River basin (NE Spain) represents a particular case of chronic and long-term mercury pollution due to the presence of an industrial waste (up to 436 μg/g of Hg) coming from a chlor-alkali plant Albeit high total mercury (THg) levels have been previously described in several aquatic species from the survey...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2011.05.004
更新日期:2011-10-01 00:00:00
abstract::A major incident of phthalate-contaminated foodstuffs happened in Taiwan between April and July, 2011. Phthalates were deliberately added to foodstuffs as a substitute of emulsifier. We describe the course of this incident, government response and management of the crisis, and its future implications. Five major food ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2012.01.014
更新日期:2012-09-01 00:00:00
abstract::Climatic factors, especially temperature, precipitation, and humidity play an important role in disease transmission. As the Arctic changes at an unprecedented rate due to climate change, understanding how climatic factors and climate change affect infectious disease rates is important for minimizing human and economi...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2018.09.042
更新日期:2018-12-01 00:00:00
abstract::The acute toxicity of citrate capped silver nanoparticles (AgNP) and silver nitrate was evaluated on the marine macroalga Ulva rigida C. Agardh (1823). Silver bioaccumulation, ultrastructural chloroplast damages verified by TEM microscopy, inhibition of primary production, neutral lipid production and oxidative stress...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.104942
更新日期:2019-10-01 00:00:00
abstract::A coupled numerical model of the atmospheric thermo-hydrodynamics and pollutant photochemical transport is described. This model can be used to study the complex relationships between the chemical and thermo-hydrodynamic processes in the atmosphere of urban areas with an emphasis on photochemical ozone formation. Prel...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/S0160-4120(02)00173-3
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Antibiotic resistance poses an increasing threat to public health. Horizontal gene transfer (HGT) promoted by antibiotics is recognized as a significant pathway to disseminate antibiotic resistance genes (ARGs). However, it is unclear whether non-antibiotic, anti-microbial (NAAM) chemicals can directly promo...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.10.040
更新日期:2018-12-01 00:00:00
abstract::Recent studies suggested a significant downward trend in population's exposure to bisphenol A (BPA) in the United States. However, the temporal trend of BPA exposure remains unclear in China - a populous country with substantial industrial activities but less efforts made to phase out BPA in consumer products. In addi...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105758
更新日期:2020-08-01 00:00:00
abstract::Veterinary and human pharmaceuticals have been widely used in the developed world, thus increasing their accumulation in the environment and thereby posing ecological risks. Earlier studies report that active pharmaceutical ingredients induce hormesis in plants, i.e. at low doses may enhance plant health whereas at hi...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2018.08.035
更新日期:2018-11-01 00:00:00
abstract::Mulching can effectively maintain and improve soil health and functionality. The mechanisms, however, have not been fully elucidated. Therefore, the effects of temperature on the biogeochemical properties of soil were investigated in the present study in relation to nitrogen management and soil functionality. The resu...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105092
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Ionization air purifiers, which purify particulate matter (PM) by producing vast number of negative air ions (NAI), are widely used. Recent study implied that ionization air purification could bring respiratory benefits but deterioration of heart rate variability (HRV). However, its underlying molecular mech...
journal_title:Environment international
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envint.2020.105663
更新日期:2020-05-01 00:00:00
abstract::Surface sediment samples were collected from various locations in the Mumbai and Kochi harbours, west coast of India, to assess the presence of butyltin compounds. Tributyltin (TBT) and dibutyltin (DBT) varied from 16 to 16,816 ng/g dry wt. and from undetected to 469 ng/g dry wt., respectively, of the sediment in Koch...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2005.08.020
更新日期:2006-02-01 00:00:00
abstract::Microbiological quality of surface waters can be affected by microbial load in runoff from grazing lands. This effect, with other factors, depends on the survival of microorganisms in animal waste deposited on pastures. Since temperature is a leading environmental parameter affecting survival, it indirectly impacts wa...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2012.12.013
更新日期:2013-04-01 00:00:00
abstract::The aim of the study was to investigate the potential spread of gentamicin resistant (GEN(R)) Escherichia coli isolates or GEN(R) determinants from a Danish university hospital to the waste water environment. Waste water samples were collected monthly from the outlets of the hospital bed wards and the inlet of the rel...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2007.07.011
更新日期:2008-01-01 00:00:00
abstract::Although various pesticides were used globally, the pesticides profiles in human blood serum remain largely unknown. We determined pesticide exposure profiles using solid-phase extraction and gas chromatography tandem with triple quadrupole mass spectrometry in 200 human blood serum samples from the adult population i...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.03.004
更新日期:2017-05-01 00:00:00