Abstract：
:Endocrine-disrupting chemicals are known to influence organismal reproductive processes, including the production and regulation of gonadal steroids. This study evaluated the effects of a xenoestrogen (nonylphenol: NP) on salmon ovarian steroidogenesis and growth factors using an in vitro organ culture system. Ovarian tissues were cultivated for 3 and 7d with different concentrations of NP (0 (control), 1, 10 and 50 microM) dissolved in ethanol (0.1%). The mRNA expressions of steroidogenic acute regulatory (StAR) protein, P450-mediated cholesterol side-chain cleavage (P450scc), aromatase isoforms, 3beta-hydroxysteroid dehydrogenase (3beta-HSD), Cyp11beta-, Cyp17 and 21-hydroxylase, and insulin-like growth factors (IGF-1 and IGF-2) and IGF1-receptor (IGF1-R) were quantified by real-time PCR. Tissue levels of estradiol-17beta (E2), testosterone (T) and 11-ketotestosterone (11-KT) were quantified using enzyme immunoassays. Our data show that nominal NP levels produced time- and concentration-specific effects on the expression of steroidogenesis- and IGF-related transcripts in salmon ovarian tissues. Tissue levels of ovarian E2, T and 11-KT were significantly modulated after NP exposure. Interestingly, elevated ovarian E2 levels after 10 microM NP exposure at day 3 paralleled P450Arom isoforms mRNA expression at the same time interval. The expression patterns of other steroidogenic protein and enzyme genes, such as StAR, P450scc, 3beta-HSD and Cyp17 inversely paralleled this pattern, displaying consistent decreased transcript levels. These findings show that NP (an ubiquitous environmental pollutant) can produce variations in gonadal steroidogenesis and growth regulating responses with potential consequences for overt fecundity in teleosts.
journal_name
Chemospherejournal_title
Chemosphereauthors
Kortner TM,Vang SH,Arukwe Adoi
10.1016/j.chemosphere.2009.07.075subject
Has Abstractpub_date
2009-11-01 00:00:00pages
989-98issue
7eissn
0045-6535issn
1879-1298pii
S0045-6535(09)00914-Xjournal_volume
77pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:In this study, anaerobic acidification of sugar beet processing wastes and subsequent liquid-liquid extraction of produced fermentation metabolites were investigated. The aim of extraction experiments was to asses the influence of pH and extractant (trioctylphosphine oxide (TOPO) in kerosene) concentrations on the rec...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.08.027
更新日期：2009-11-01 00:00:00
abstract：:Although atrazine has been banned in the European Union since 2007 it still persists in soil from where it can enter the food chain. Milk-producing animals accumulate atrazine from contaminated feed and water and since large quantities of milk and milk products are consumed its quality should be constantly monitored. ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.02.016
更新日期：2012-06-01 00:00:00
abstract：:Synthetic musks, chemical constituents of personal care products, enter the human body through dermal contact. Elucidation of the mechanisms underlying transdermal permeation of synthetic musks should enhance our understanding of their uptake and distribution in human skin and allow accurate evaluation of associated h...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.01.001
更新日期：2017-04-01 00:00:00
abstract：:Speciation of respirable particles is becoming increasingly important from an epidemiological and analytical point of view to determine the potential effects of air pollution on human health. For this reason, current laws and analytical sampling methods focus on particle size, as it turns out to be the main factor for...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127482
更新日期：2020-11-01 00:00:00
abstract：:The effects of the Xingou landfill leachate on levels of thiobarbituric acid reactive substances (TBARS) and the activities of Cu, Zn-superoxide dismutase (Cu, Zn-SOD), Se-dependent glutathione peroxidase (Se-dependent GPx) and catalase (CAT) were investigated in hearts, kidneys and spleens of Kunming albino mice of b...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.02.056
更新日期：2006-11-01 00:00:00
abstract：:Mussels, such as the marine bivalve Mytilus galloprovincialis are sentinels for marine pollution but they are also excellent bioindicators under laboratory conditions. For that, in this study we tested the modulation of biochemical responses under realistic concentrations of the toxic metal Lead (Pb) in water for 28 d...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.05.221
更新日期：2019-11-01 00:00:00
abstract：:In this study, we examined the influence of oxygen on the degradation of di (2-ethylhexyl) phthalate (DEHP), the accumulation of its monoester metabolite mono (2-ethylhexyl) phthalate (MEHP) and their impact on soil bacterial communities. Soil microcosms artificially contaminated with DEHP (0, 100 and 1000 mg kg-1) we...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.10.078
更新日期：2019-02-01 00:00:00
abstract：:A batch experiment was conducted to assess the impact of chemical oxidation using modified Fenton reaction on PAH content and on physico-chemical and biological parameters of an industrial PAH contaminated soil in unsaturated condition. Two levels of oxidant (H(2)O(2), 6 and 65 g kg(-1)) and FeSO(4) were applied. Agro...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.11.018
更新日期：2012-02-01 00:00:00
abstract：:Carboxylic graphene oxide (GO-COOH) is decorated with akaganeite (β-FeOOH) to produce a β-FeOOH@GO-COOH nanocomposite. The nanocomposite acts as an efficient adsorption medium for the uptake of arsenite and arsenate within a wide range of pH 3-10, providing high adsorption capacities of 77.5mgg(-1) for As(III) and 45....
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.02.046
更新日期：2015-07-01 00:00:00
abstract：:Dolphins are considered sentinel species in the marine environment. The Strait of Gibraltar is the only passage between the Mediterranean Sea and the Atlantic Ocean, being the transitional region which connects these two basins and one of the most important routes of cetacean migration worldwide. In this work, eight t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.12.009
更新日期：2017-03-01 00:00:00
abstract：AIM:We aimed to assess if snoring and ambient air pollutants were jointly associated with prevalent hypertension in a cross-sectional study. METHODS:A total of 28440 participants aged 18-79 years were obtained from the Henan Rural Cohort. Snoring evaluated using Pittsburgh sleep quality index (PSQI) scale was classifi...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127108
更新日期：2020-10-01 00:00:00
abstract：:Human activities have caused increasing inputs of pharmaceuticals to the environment and diclofenac (DF) is one of the most commonly detected in freshwater systems. The aim of this study was to determine the impact of DF on a freshwater green alga as a non-target organism. For DF toxicity evaluation, its effects on a ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.06.156
更新日期：2018-10-01 00:00:00
abstract：:This paper reports on the effect of aqueous and nano-particulated Pb on oxidative stress (lipid peroxidation), cytoxicity, and cell mortality. As determined by the Thiobarbituric Acid Reactive Substances (TBARS) method, only 6h after incubation aqueous suspensions bearing nano-sized PbO(2), soluble Pb(II), and brain-h...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.05.018
更新日期：2011-09-01 00:00:00
abstract：:The presence of 2,4,6-Tribromophenol (TBP) in the environment increased the risk of exposure to aquatic organisms affecting the animal development or metabolism. The current study investigated the low, subchronic and trophic effect of TBP in both, male and female adult of Oreochromis niloticus. The fish were exposed t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.128785
更新日期：2020-10-29 00:00:00
abstract：:In several countries such as the Netherlands, consumption of eel from polluted waters is not allowed because the concentrations of polychlorinated biphenyls (PCBs) exceed official tolerance limits. Few experiments have been carried out to assess if pre-treatment, such as cooking and frying would alter the PCB concentr...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.07.042
更新日期：2013-01-01 00:00:00
abstract：:The widespread occurrence of synthetic antibiotic sulfamethoxazole (SMX)- poses a potential risk to aquatic ecosystems where dissolved organic matter (DOM) may affect its photolysis. In this study, the elimination of SMX by solar photolysis was investigated in the presence of leonardite humic acid (LHA) and its fracti...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.125642
更新日期：2020-05-01 00:00:00
abstract：:The hygroscopicity of aerosols is dependent upon their chemical composition. When their chemical compositions are altered, the water content in aerosols often changes, which may further modify phase behaviour. However, the study of phase behaviour dependence on chemical reactions is still limited. In this work, intern...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.10.062
更新日期：2019-01-01 00:00:00
abstract：:Zinc oxide (ZnO) nanorods were prepared by a directly pyrolysis method and employed as catalyst for perfluorooctanoic acid (PFOA) degradation. Comparative experiments were conducted to discuss the catalytic activity and flexibility of ZnO. After ZnO addition, the best PFOA degradation efficiency (70.5%) was achieved b...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.03.127
更新日期：2017-08-01 00:00:00
abstract：:The oil drilling process generates large volumes of waste with inadequate treatments. Here, oil drilling waste (ODW) microbial communities demonstrate different hydrocarbon degradative abilities when exposed to distinct nutrient enrichments as revealed by comparative metagenomics. The ODW was enriched in Luria Broth (...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.06.068
更新日期：2018-10-01 00:00:00
abstract：:In situ measurements of air and water phases at a wastewater treatment plant (WWTP) were used to investigate the partitioning behavior of perfluorocarboxylic acids (PFCAs), perfluorosulfonic acids (PFSAs) and perfluorooctyl sulfonamide (HFOSA) and their conjugate bases (PFC(-)s, PFS(-)s, and FOSA(-), respectively). Pa...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.02.067
更新日期：2013-08-01 00:00:00
abstract：:Biological indices, biomarkers (EROD activity, DNA SB, 1-OH pyrene), and organochlorine contaminants were investigated in flounder collected in the Gulf of Gdańsk during March-December 2011 to describe their seasonal variability and interrelations. Univariate and multivariate statistics were used to evaluate the relat...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.12.039
更新日期：2018-03-01 00:00:00
abstract：:Due to their widespread use, organophosphate flame retardants (OPFRs) are commonly detected in various environmental matrices and have been identified as emerging contaminants. Considering the adverse effects of OPFRs, many researchers have paid their attention on the absorption, bioaccumulation, metabolism and intern...
journal_title：Chemosphere
pub_type： 杂志文章,评审
doi：10.1016/j.chemosphere.2016.03.003
更新日期：2016-06-01 00:00:00
abstract：:Due to influence of wind patterns (monsoon and westerlies) and anthropogenic activities, lower stretch of Himalaya is at direct exposure to persistent organic pollutants (POPs). Current study was designed to monitor atmospheric concentrations of long lived organochlorine pesticides (OCPs) and polychlorinated biphenyls...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.10.021
更新日期：2018-01-01 00:00:00
abstract：:A modified quick, easy, cheap, efficient, rugged and safe method (QuEChERS) coupled to gas chromatography with electron capture detector (GC-ECD) was developed for rapid extraction and simultaneous determination of 36 pesticides in lotus seeds. The extraction solvent (acetone, ethyl acetate, acetonitrile, n-hexane and...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.01.104
更新日期：2013-05-01 00:00:00
abstract：:With the increasing impact of the global warming, occurrences of cyanobacterial blooms in aquatic ecosystems are becoming a main worldwide ecological concern. Due to their capacity to produce potential toxic metabolites, interactions between the cyanobacteria, their cyanotoxins and the surrounding freshwater organisms...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.03.115
更新日期：2019-07-01 00:00:00
abstract：:Using the potentiometric titration and pK spectroscopy method, acid-base properties of water-soluble organic matter of forest soils have been studied. Five acidic classes composed of different substances with pK(a) values around 3.6; 4.8; 6.7; 8.7 and 9.7 have been identified. Testing the properties of soluble soil fr...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.03.057
更新日期：2006-11-01 00:00:00
abstract：:In order to obtain basic information for designing standardized test preparation methods, the heavy metals Zn, Cu, Cd and Pb were measured in gastropods (Xerolenta obvia), oligochaetes (Lumbricus terrestris), isopods (Armadillidium vulgare, Trachelipus rathkei) and carabids (Harpalus rubripes, Calathus fuscipes) using...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/S0045-6535(03)00442-9
更新日期：2003-08-01 00:00:00
abstract：:PAH emission from the powered engines fueled by a 95 leadfree gasoline (95-LFG), a 92 leadfree gasoline (92-LFG) and a Premium leaded gasoline (PLG) with two gasoline additives (SA and SB) were collected using a PAH sampling system with a particulate interception device. Twenty one PAHs were analyzed primarily by an G...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(97)10088-1
更新日期：1998-04-01 00:00:00
abstract：:This paper provides a circular win-win approach for recycling rhizofiltration biomass into multifunctional engineered biochar for various environmental applications (e.g. phosphate recovery) with a potential reuse of the exhausted biochar as an enriched soil amendment. Functionalized biochars were derived from the dis...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.01.113
更新日期：2018-05-01 00:00:00
abstract：:The performance of miniaturized microbial fuel cells operating with five different substrates (acetate, lactate, glucose and octanoate) were studied with the aim to identify the reason for its different performance. In all cases, the COD removal rate was about 650 mg COD L-1 d-1. However, the bio-electrochemical perfo...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.05.100
更新日期：2018-09-01 00:00:00
