Abstract：
:African cichlid fishes are a prime model for studying speciation mechanisms. Despite the development of extensive genomic resources, it has been difficult to determine which sources of genetic variation are responsible for cichlid phenotypic variation. One of their most variable phenotypes is visual sensitivity, with some of the largest spectral shifts among vertebrates. These shifts arise primarily from differential expression of seven cone opsin genes. By mapping expression quantitative trait loci (eQTL) in intergeneric crosses of Lake Malawi cichlids, we previously identified four causative genetic variants that correspond to indels in the promoters of either key transcription factors or an opsin gene. In this comprehensive study, we show that these indels are the result of the movement of transposable elements (TEs) that correlate with opsin expression variation across the Malawi flock. In tracking the evolutionary history of these particular indels, we found they are endemic to Lake Malawi, suggesting that these TEs are recently active and are segregating within the Malawi cichlid lineage. However, an independent indel has arisen at a similar genomic location in one locus outside of the Malawi flock. The convergence in TE movement suggests these loci are primed for TE insertion and subsequent deletions. Increased TE mobility may be associated with interspecific hybridization, which disrupts mechanisms of TE suppression. This might provide a link between cichlid hybridization and accelerated regulatory variation. Overall, our study suggests that TEs may be an important driver of key regulatory changes, facilitating rapid phenotypic change and possibly speciation in African cichlids.
journal_name
Mol Ecoljournal_title
Molecular ecologyauthors
Carleton KL,Conte MA,Malinsky M,Nandamuri SP,Sandkam BA,Meier JI,Mwaiko S,Seehausen O,Kocher TDdoi
10.1111/mec.15685subject
Has Abstractpub_date
2020-12-01 00:00:00pages
4956-4969issue
24eissn
0962-1083issn
1365-294Xjournal_volume
29pub_type
杂志文章abstract：:Understanding how phenotypic variation is generated and maintained, and the evolutionary forces that shape these processes is the main goal of evolutionary biology. Great progress has been made in uncovering the genetic basis of morphological diversity, yet little is known about both the genetics and developmental bas...
journal_title：Molecular ecology
pub_type： 评论,新闻
doi：10.1111/mec.14099
更新日期：2017-05-01 00:00:00
abstract：:The early stages of invasion involve demographic bottlenecks that may result in lower genetic variation in introduced populations as compared to source population/s. Low genetic variability may decrease the adaptive potential of such populations in their new environments. Previous population genetic studies of invasiv...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2008.03866.x
更新日期：2008-08-01 00:00:00
abstract：:The desert locust (Schistocerca gregaria) undergoes crowding-induced phase transformation from solitary form to gregarious form. The transformations involves changes in behaviour, colour, development, morphometry, fecundity and endocrine physiology. Recession populations of the desert locust exist primarily in the sol...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2001.01212.x
更新日期：2001-03-01 00:00:00
abstract：:High-latitude ecotonal populations at the species margins may exhibit altered patterns of genetic diversity, resulting from more or less recent founder events and from bottleneck effects in response to climate oscillations. Patterns of genetic diversity were investigated in nine populations of the conifer black spruce...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2003.01800.x
更新日期：2003-04-01 00:00:00
abstract：:Within the framework of landscape genetics, resistance surface modelling is particularly relevant to explicitly test competing hypotheses about landscape effects on gene flow. To investigate how fragmentation of tropical forest affects population connectivity in a forest specialist bird species, we optimized resistanc...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.14233
更新日期：2017-10-01 00:00:00
abstract：:Levels and origins of clonal diversity in asexual hybrid animals are critical to understanding how they can coexist with their sexual progenitor species. In this study, asexual gynogenetic hybrids between Fundulus diaphanus and Fundulus heteroclitus known from two sites in Nova Scotia (Canada) were characterized using...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2007.03239.x
更新日期：2007-04-01 00:00:00
abstract：:Aphis gossypii is an aphid species that is found throughout the world and is extremely polyphagous. It is considered a major pest of cotton and cucurbit species. In Europe, A. gossypii is assumed to reproduce exclusively by apomictic parthenogenesis. The present study investigates the genetic diversity of A. gossypii ...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.1999.00782.x
更新日期：1999-11-01 00:00:00
abstract：:Genetic diversity and its partition within and among populations and families of two species of Antirrhinum L., A. charidemi Lange and A. valentinum F.Q., have been studied. Both species are narrow-range endemics, self-incompatible, ecologically specialized and form small isolated populations. Despite these similariti...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2000.01119.x
更新日期：2000-12-01 00:00:00
abstract：:We present a de novo assembly of a eukaryote transcriptome using 454 pyrosequencing data. The Glanville fritillary butterfly (Melitaea cinxia; Lepidoptera: Nymphalidae) is a prominent species in population biology but had no previous genomic data. Sequencing runs using two normalized complementary DNA collections from...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2008.03666.x
更新日期：2008-04-01 00:00:00
abstract：:Mutation rates at microsatellites tend to increase with the number of repeats of the motif, leading to higher levels of polymorphism at long microsatellites. To standardize levels of diversity when microsatellites differ in size, we investigate the relationship between tract length and variation and provide a formula ...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2005.02446.x
更新日期：2005-03-01 00:00:00
abstract：:Multiple introductions are key features for the establishment and persistence of introduced species. However, little is known about the contribution of genetic admixture to the invasive potential of populations. To address this issue, we studied the recent invasion of the Asian tiger mosquito (Aedes albopictus) in Eur...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.15071
更新日期：2019-05-01 00:00:00
abstract：:The analysis of mitochondrial DNA sequences has for a long time been the most extensively used genetic tool for phylogenetic, phylogeographic and population genetic studies. Since this approach only considers female lineages, it tends to give a biased picture of the population history. The use of protein polymorphisms...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2001.01326.x
更新日期：2001-08-01 00:00:00
abstract：:Genetic diversity and fine-scale population structure in the lichen-forming ascomycete Xanthoria parietina was investigated using sequence variation in part of the intergenic spacer (IGS) and the complete internal transcribed spacer (ITS) regions of the nuclear ribosomal DNA. Sampling included 213 and 225 individuals,...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2006.02880.x
更新日期：2006-05-01 00:00:00
abstract：:Reproducibility is the benchmark for results and conclusions drawn from scientific studies, but systematic studies on the reproducibility of scientific results are surprisingly rare. Moreover, many modern statistical methods make use of 'random walk' model fitting procedures, and these are inherently stochastic in the...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2012.05754.x
更新日期：2012-10-01 00:00:00
abstract：:Biological invasions comprise accidental evolutionary experiments, whose genetic compositions underlie relative success, spread and persistence in new habitats. However, little is known about whether, or how, their population genetic patterns change temporally and/or spatially across the invasion's history. Theory pre...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.13997
更新日期：2017-02-01 00:00:00
abstract：:Microsatellites are one of the most important classes of nuclear genetic markers and offer many advantages for the study of marine mammals. Here we describe the isolation and characterization of 12 cetacean microsatellites which are then tested across 30 different cetacean species. For around half the species tested, ...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294x.1996.tb00301.x
更新日期：1996-02-01 00:00:00
abstract：:Experimental studies of the interaction between host and symbiont in a maturing symbiotic organ have presented a challenge for most animal-bacterial associations. Advances in the rearing of the host squid Euprymna scolopes have enabled us to explore the relationship between a defect in symbiont light production and la...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.12474
更新日期：2014-03-01 00:00:00
abstract：:Medicago citrina is an endangered western Mediterranean endemic that grows only on small islets of the Balearic archipelago and off the eastern Spanish coast. Only 10 isolated subpopulations are currently known (four from Ibiza, three from Cabrera, two from Columbretes and one from an offshore islet in northern Alican...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2004.02289.x
更新日期：2004-09-01 00:00:00
abstract：:The ecological and genetic factors determining the extent of introgression between species in secondary contact zones remain poorly understood. Here, we investigate the relative importance of isolating barriers and the demographic expansion of invasive Mytilus galloprovincialis on the magnitude and the direction of in...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.13340
更新日期：2015-09-01 00:00:00
abstract：:Many insects possess endosymbiotic bacteria inside their body, wherein intimate interactions occur between the partners. While recent technological advancements have deepened our understanding of metabolic and evolutionary features of the symbiont genomes, molecular mechanisms underpinning the intimate interactions re...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/mec.12479
更新日期：2014-03-01 00:00:00
abstract：:Sixty-four samples from 46 salmon populations totalling 2369 specimens were used for polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of the mitochondrial ND1 region. The final analyses included 3095 specimens from 60 populations in Northern Europe. A subsample was analysed by RFL...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2001.01168.x
更新日期：2001-01-01 00:00:00
abstract：:Fossil, archaeological, and morphometric data suggest that indigenous red foxes in North America were derived from vicariance in two disjunct refugia during the last glaciation: one in Beringia and one in the contiguous USA. To test this hypothesis, we conducted a phylogeographical analysis of the North American red f...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2009.04222.x
更新日期：2009-06-01 00:00:00
abstract：:Organisms often respond to environmental changes by producing alternative phenotypes. Epigenetic processes such as DNA methylation may contribute to environmentally induced phenotypic variation by modifying gene expression. Changes in DNA methylation, unlike DNA mutations, can be influenced by the environment; they ar...
journal_title：Molecular ecology
pub_type： 杂志文章,评审
doi：10.1111/j.1365-294X.2010.04580.x
更新日期：2010-04-01 00:00:00
abstract：:The populations of the bivalve clam Macoma balthica in the low-salinity Northern Baltic Sea represent an admixture of two strongly diverged genomic origins, the Pacific Macoma balthica balthica (approx. 60% genomic contribution) and Atlantic Macoma balthica rubra (40%). Using allozyme and mtDNA characters, we describe...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2007.03688.x
更新日期：2008-03-01 00:00:00
abstract：:Studies of a hybrid zone between two house mouse subspecies (Mus musculus musculus and M. m. domesticus) along with studies using laboratory crosses reveal a large role for the X chromosome and multiple autosomal regions in reproductive isolation as a consequence of disrupted epistasis in hybrids. One limitation of pr...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2012.05583.x
更新日期：2012-06-01 00:00:00
abstract：:Contemporary North American drainage basins are composites of formerly isolated drainages, suggesting that fragmentation and fusion of palaeodrainage systems may have been an important factor generating current patterns of genetic and species diversity in stream-associated organisms. Here, we combine traditional molec...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2005.02757.x
更新日期：2006-01-01 00:00:00
abstract：:Studies examining the effects of anthropogenic habitat fragmentation on both neutral and adaptive genetic variability are still scarce. We compared tadpole fitness-related traits (viz. survival probability and body size) among populations of the common frog (Rana temporaria) from fragmented (F) and continuous (C) habi...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2007.03357.x
更新日期：2007-07-01 00:00:00
abstract：:Sex identification is a problem in research and conservation. It can often be solved using a DNA test but this is only an option if a sex-specific marker is available. Such markers can be identified using the amplified fragment length polymorphism (AFLP) technique. This is usually a taxonomic method, as it produces a ...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.1999.00578.x
更新日期：1999-04-01 00:00:00
abstract：:The origin of eusociality in haplo-diploid organisms such as Hymenoptera has been mostly explained by kin selection. However, several studies have uncovered decreased relatedness values within colonies, resulting primarily from multiple queen matings (polyandry) and/or from the presence of more than one functional que...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1046/j.1365-294x.2002.01573.x
更新日期：2002-09-01 00:00:00
abstract：:Linear and heterogeneous habitat makes headwater stream networks an ideal ecosystem in which to test the influence of environmental factors on spatial genetic patterns of obligatory aquatic species. We investigated fine-scale population structure and influence of stream habitat on individual-level genetic differentiat...
journal_title：Molecular ecology
pub_type： 杂志文章
doi：10.1111/j.1365-294X.2011.05210.x
更新日期：2011-09-01 00:00:00
