Abstract:
AIMS:Chronic pudendal nerve stimulation (CPNS) is a logical alternative particularly in those who fail sacral stimulation. We evaluated symptoms, complications, and satisfaction after CPNS. METHODS:We retrospectively reviewed patients having a tined lead placed at the pudendal nerve via the ischial-rectal approach. Demographics, history, complications, and pre-implant voiding diary data were collected. In those responding to CPNS, post-implant symptom changes were measured with the Interstitial Cystitis Symptom and Problem indices (ICSI-PI) and voiding diaries at 3, 6, and 12 months, and a mailed survey. RESULTS:The majority of 84 patients (78.6% female; age 51.8 ± 16.9 years) had interstitial cystitis/painful bladder syndrome, or overactive bladder. Pudendal response (≥ 50% improvement) occurred in 60/84 (71.4%), however 5 of these chose sacral neuromodulation. Almost all (93.2%) who had previously failed sacral neuromodulation responded to pudendal stimulation. Outcomes were evaluated in 55 continuing on CPNS (median follow up 24.1 months). Seven complications requiring 5 revisions, and 4 other re-operations occurred. Five were explanted. Over time, significant improvements in frequency (P < 0.0001), voided volume (P < 0.0001), incontinence (P < 0.0001), and urgency (P = 0.0019) occurred. ICSI-PI scores significantly improved over 12 months (P < 0.0001). Survey responses indicated that most still had a device (35/40; 87.5%) continuously in use (24/29; 82.8%), and overall bladder, pelvic pain, incontinence, urgency, and frequency symptoms had improved. CONCLUSIONS:CPNS is a reasonable alternative in complex patients refractory to other therapies including sacral neuromodulation. Continued research is needed to fully assess long-term outcomes and identify predictors of success.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Peters KM,Killinger KA,Boguslawski BM,Boura JAdoi
10.1002/nau.20823subject
Has Abstractpub_date
2010-09-01 00:00:00pages
1267-71issue
7eissn
0733-2467issn
1520-6777journal_volume
29pub_type
杂志文章abstract::Investigations of micromotion characteristics of bladder wall strips and pressure wave phenomena in total bladders in vitro and in vivo indicate that micromotion phenomena occur in the bladder wall. Local contractions can occur without an increase in tension or pressure, because other parts are in antiphase. Local con...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930120504
更新日期:1993-01-01 00:00:00
abstract:AIM:To elucidate the precise cellular and molecular mechanisms that underlie urethral fibrogenesis. METHODS:Endoluminal electrocautery injury (using Karl Storz 10 Fr. Pediatric urethroscope) was employed in male rabbits (n = 6) to create mucosal injury. Retrograde urethrogram (RUG) and endoluminal ultrasound technique...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24281
更新日期:2020-02-01 00:00:00
abstract:AIMS:Estrogen is essential for physiological maintenance of the female urogenital tract. It is believed that alterations in female sex hormones play a major role in the etiology and response to urinary tract dysfunctions. In animal studies, ovariectomy (Ovx) results in smooth muscle (SM) weakness and atrophy whereas es...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20258
更新日期:2006-01-01 00:00:00
abstract:AIMS:The objective of this document created by the ICCS standardization subcommittee is to provide a uniform guideline on measurement, quality control and documentation of urodynamic studies in children. METHODS:This guideline was created using expert opinion and critical review of the published literature on urodynam...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,实务指引,评审
doi:10.1002/nau.22783
更新日期:2015-09-01 00:00:00
abstract:AIMS:To study the influence of bladder pumping on the urinary bladder in 44 female rats. METHODS:Under halothane anesthesia, a urethral catheter was inserted into the bladder of 27 rats, and air (0.4-0.8 mL) was pumped in and out of the bladder at 0.5 cycles/second for a period of 5 minutes. Twenty-four hours after pu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10048
更新日期:2002-01-01 00:00:00
abstract:AIMS:To investigate the effect of the bladder sensation grade on uroflowmetry parameters. METHODS:Fifty healthy volunteering young men were enrolled in the present study. In total, three uroflowmetry evaluations were made. Qmax , Qave , VV, and PVR urine was obtained three times in three described bladder sensation gr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22762
更新日期:2016-06-01 00:00:00
abstract:AIM:Characterize clinical factors related to nocturia and sleep disruption in Parkinson disease (PD) using polysomnography (PSG). METHODS:Sixty-three PD patients were recruited regardless of sleep or voiding complaints from a university-based movement disorders clinic for a 48 hr inpatient PSG protocol. Nocturia frequ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22365
更新日期:2013-11-01 00:00:00
abstract:AIMS:To evaluate the effect of ASP2205, a selective serotonin 5-HT2c receptor agonist, and Duloxetine on the urethral pressure in healthy female subjects. METHODS:Healthy females aged 18 to 55 years were recruited for this phase 1, single site, placebo-controlled, randomized, four-period, cross-over study. The interve...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.24045
更新日期:2019-08-01 00:00:00
abstract::The response of the abdominal muscles to voluntary contraction of the pelvic floor (PF) muscles was investigated in women with no history of symptoms of stress urinary incontinence to determine whether there is co-activation of the muscles surrounding the abdominal cavity during exercises for the PF muscles. Electromy...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/1520-6777(2001)20:1<31::aid-nau5>3.0.co;2-
更新日期:2001-01-01 00:00:00
abstract::Following use of botulinum toxin in the 1980s for the treatment of detrusor sphincter dyssynergia in patients with spinal cord injury (SCI), the potential therapeutic value of this neurotoxin in urology has been the subject of much interest. The DIGNITY (Double-blind InvestiGation of purified Neurotoxin complex In neu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22630
更新日期:2014-07-01 00:00:00
abstract:AIMS:We sought to compare in-office physical exam findings via standing cough test (SCT) versus 24-hour pad weights among men seeking treatment for postprostatectomy stress urinary incontinence (SUI). METHODS:A retrospective review of a single surgeon database of incontinence procedures was performed. Documentation of...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24200
更新日期:2020-01-01 00:00:00
abstract:AIMS:Firm bladder neck support during cough, suggested to be needed for effective abdominal pressure transmission to the urethra, might depend on activity of the levator ani muscle and elasticity of endopelvic fascia. METHODS:The study group of 32 patients with stress urinary incontinence and hypermobile bladder neck,...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10116
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The objective of our study was to investigate the prevalence and risk of developing stress urinary incontinence (SUI) in each type of high-intensity sport, and the associated impact on quality of life in sportswomen. METHODS:This cross-sectional study was conducted between March and November 2016. The study ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23538
更新日期:2018-08-01 00:00:00
abstract::The present study prospectively surveyed the prevalence of anal incontinence among 283 consecutive female patients attending a urogynecologic outpatient clinic in a maternity hospital. Data concerning bowel habits, laxative use, previous anorectal surgery, and the presence, severity, and frequency of anal incontinence...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(1999)18:3<199::aid-nau6>3.
更新日期:1999-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24109
更新日期:2019-09-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(2000)19:2<137::aid-nau4>3.
更新日期:2000-01-01 00:00:00
abstract:AIMS:Botulinum toxin A (BTX-A) and sacral nerve stimulation (SNS) are established treatments for overactive bladder (OAB) and are standard of care in refractory cases in international guidelines. Despite long term use over decades their "exact" working mechanisms are not entirely clear. At the ICI-RS meeting in Bristol...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.23552
更新日期:2018-06-01 00:00:00
abstract:AIM:Interstitial cystitis/painful bladder syndrome/(IC/PBS) results in recurring pain in the bladder and surrounding pelvic region caused by abnormal excitability of micturition reflexes. Spinal cord stimulation (SCS) is currently clinically used for the attenuation of neuropathic and visceral pain. The present study e...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23827
更新日期:2019-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21193
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24234
更新日期:2020-02-01 00:00:00
abstract::This is the first report of the International Continence Society (ICS) on the development of comprehensive guidelines for Good Urodynamic Practice for the measurement, quality control, and documentation of urodynamic investigations in both clinical and research environments. This report focuses on the most common urod...
journal_title:Neurourology and urodynamics
pub_type: 指南,杂志文章,实务指引
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更新日期:2002-01-01 00:00:00
abstract:AIMS:To evaluate the impacts of hydrogen sulfide (H2 S) donor, sodium hydrogen sulfide (NaHS), and phosphodiesterase type-5 inhibitor (PDE5i), tadalafil per se and their combination treatment on partial bladder outlet obstruction (PBOO)-induced erectile dysfunction (ED). METHODS:Sprague-Dawley rats were equally divide...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24333
更新日期:2020-04-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22509
更新日期:2015-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.23050
更新日期:2017-04-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22344
更新日期:2013-09-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22205
更新日期:2012-09-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140206
更新日期:1995-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24415
更新日期:2020-08-01 00:00:00
abstract::Detrusor hyperreflexia (DH) is frequently found in patients with benign prostatic hypertrophy (BPH) and persists in 30-50% of patients after successful removal of bladder neck obstruction by transurethral prostatectomy (TUR-P) or surgical enucleation of the prostate. It would be beneficial for surgeons to be able to i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(2000)19:3<233::aid-nau4>3.
更新日期:2000-01-01 00:00:00