Vibration stimulates vocal mucosa-like matrix expression by hydrogel-encapsulated fibroblasts.

abstract：:The full-thickness skin wound is a common skin complication affecting millions of people worldwide. Delayed treatment of this condition causes the loss of skin function and integrity that could lead to the development of chronic wounds or even death. This study was aimed to develop a rapid wound treatment modality usi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Mh Busra F,Rajab NF,Tabata Y,Saim AB,B H Idrus R,Chowdhury SR

更新日期：2019-05-01 00:00:00

abstract：:Transplantation of bone marrow mesenchymal stem cells (BMSCs) has been considered to be a promising strategy for wound healing. However, poor viability of engrafted BMSCs and limited capabilities of differentiation into the desired cell types in wounds often hinder its application. Few studies report the induction of ...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Shou K,Huang Y,Qi B,Hu X,Ma Z,Lu A,Jian C,Zhang L,Yu A

更新日期：2018-02-01 00:00:00

abstract：:Tissue-engineering strategies may be employed in the development of in vitro breast tissue models for use in testing regimens of drug therapies and vaccines. The physical and chemical interactions that occur among cells and extracellular matrix components can also be elucidated with these models to gain an understandi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Parzel CA,Pepper ME,Burg T,Groff RE,Burg KJ

更新日期：2009-06-01 00:00:00

abstract：:The self-regeneration capacity of articular cartilage is limited, due to its avascular and aneural nature. Loaded explants and cell cultures demonstrated that chondrocyte metabolism can be regulated via physiologic loading. However, the explicit ranges of mechanical stimuli that correspond to favourable metabolic resp...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Tasci A,Ferguson SJ,Büchler P

更新日期：2011-03-01 00:00:00

abstract：:A highly efficient cardiac differentiation from human pluripotent stem cells (hPSCs) is achievable using existing methods, especially with the standard B27 induction system. However, bovine serum albumin (BSA), one of the essential ingredients in B27, may pose significant complications for clinical studies owing to it...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Tan Y,Han P,Gu Q,Chen G,Wang L,Ma R,Wu J,Feng C,Zhang Y,Wang L,Hu B,Li W,Hao J,Zhou Q

更新日期：2018-01-01 00:00:00

abstract：:The advances achieved by cell-based therapies to treat autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis (MS), despite promising, are still insufficient for the current demands. RA and MS therapeutic approaches follow world guidelines to use disease modifying drugs and biological agents that...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Rodrigues DB,Oliveira JM,Santos TC,Reis RL

更新日期：2018-03-01 00:00:00

abstract：:Despite the high prevalence of skin conditions in the horse, there is a dearth of literature on the culture and biology of equine skin cells, and this is partially attributable to the lack of suitable in vitro skin models. The objective of this study was to develop a three-dimensional (3D) culture system that would su...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Sharma R,Barakzai SZ,Taylor SE,Donadeu FX

更新日期：2016-08-01 00:00:00

abstract：:Cleft palate is one of the most common craniofacial defects in newborn babies. The characteristics of this genetic disease produce soft and hard tissue defects on the lip and maxilla, which cause not only aesthetic but also functional problems with speech, eating, and breathing. Bone grafts using autologous cancellous...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Lee JM,Kim HY,Park JS,Lee DJ,Zhang S,Green DW,Okano T,Hong JH,Jung HS

更新日期：2019-02-01 00:00:00

abstract：:Obtaining an efficient, uniform and reproducible cell seeding of porous tubular scaffolds constitutes a major challenge for the successful development of tissue-engineered vascular grafts. In this study, a novel automated cell-seeding device utilizing direct cell deposition, patterning techniques and scaffold rotation...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Mohebbi-Kalhori D,Rukhlova M,Ajji A,Bureau M,Moreno MJ

更新日期：2012-10-01 00:00:00

abstract：:The aim of this study was to establish the potential of human periosteum-derived cells from elderly patients as a cell source for cartilage tissue engineering by optimizing culture conditions for both proliferation and differentiation. Periosteum was obtained from the tibiae of nine patients. Biopsies were prepared fo...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Jansen EJ,Emans PJ,Guldemond NA,van Rhijn LW,Welting TJ,Bulstra SK,Kuijer R

更新日期：2008-08-01 00:00:00

abstract：:Prevascularization is essential to ensure the viability, functionality, and successful integration of tissue-engineered three-dimensional (3D) constructs with surrounding host tissues after transplantation. Human mesenchymal stem cell (hMSC) sheet can be prevascularized by coculturing with endothelial cells (ECs), and...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Jia W,Sharma D,He W,Xing Q,Zhao F

更新日期：2021-01-11 00:00:00

abstract：:Bone extracellular matrix (ECM) is composed of mineralized collagen fibrils which support biological apatite nucleation that participates in bone outstanding properties. Understanding and mimicking bone morphological and physiological parameters at a biological scale is a major challenge in tissue engineering scaffold...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Rodrigues MT,Martins A,Dias IR,Viegas CA,Neves NM,Gomes ME,Reis RL

更新日期：2012-11-01 00:00:00

abstract：:Research in regenerative medicine is developing at a significantly quick pace. Cell-based bone and cartilage replacement is an evolving therapy aiming at the treatment of patients who suffer from limb amputation, damaged tissues and various bone and cartilage-related disorders. Stem cells are undifferentiated cells wi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： El Tamer MK,Reis RL

更新日期：2009-07-01 00:00:00

abstract：:Current approaches for precision deposition of cells are not optimized for moist environments or for substrates with complex surface topographic features, for example, the surface of dermal matrices and other biomaterials. To overcome these challenges, an approach is presented that utilizes cell confinement in phase-s...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Agarwal R,Liu G,Tam NW,Gratzer PF,Frampton JP

更新日期：2019-06-01 00:00:00

abstract：:Cartilage tissue engineering is making progress, but the competing available strategies still leave room for improvement and consensual overviews regarding the best combinations of scaffolds and cell sources are limited by the capacity to compare them directly. In addition, because most strategies involve autologous c...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Henrionnet C,Gillet P,Mainard D,Vincourt JB,Pinzano A

更新日期：2018-03-01 00:00:00

abstract：:Manufacture of red blood cells (RBCs) from progenitors has been proposed as a method to reduce reliance on donors. Such a process would need to be extremely efficient for economic viability given a relatively low value product and high (2 × 1012 ) cell dose. Therefore, the aim of these studies was to define the produc...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Bayley R,Ahmed F,Glen K,McCall M,Stacey A,Thomas R

更新日期：2018-01-01 00:00:00

abstract：:The successful integration of in vitro-generated tissues is dependent on adequate vascularization in vivo. Human outgrowth endothelial cells (OECs) isolated from the mononuclear cell fraction of peripheral blood represent a potent population of circulating endothelial progenitors that could provide a cell source for r...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Ghanaati S,Fuchs S,Webber MJ,Orth C,Barbeck M,Gomes ME,Reis RL,Kirkpatrick CJ

更新日期：2011-06-01 00:00:00

abstract：:Macroporous calcium phosphate cement (CPC) with stem cell seeding is promising for bone regeneration. The objective of this study was to investigate the effects of co-delivering autologous bone marrow mesenchymal stem cells (BMSCs) and autologous platelet-rich plasma (PRP) in CPC scaffold for bone regeneration in mini...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Qiu G,Shi Z,Xu HHK,Yang B,Weir MD,Li G,Song Y,Wang J,Hu K,Wang P,Zhao L

更新日期：2018-02-01 00:00:00

abstract：:New injectable acrylic formulations have been prepared to be applied in restoration processes for intervertebral disks (IVDs). The solid phase of the formulations is composed of poly(methyl methacrylate) (PMMA), incorporating in some cases chondroitin sulphate (CS) as a regenerative bioactive molecule, whereas the liq...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Larraz E,Elvira C,Fernández M,Parra J,Collía F,López-Bravo A,Román JS

更新日期：2007-03-01 00:00:00

abstract：:The gastroesophageal junction has been of clinical interest for some time due to its important role in preventing reflux of caustic stomach contents upward into the esophagus. Failure of this role has been identified as a key driver in gastroesophageal reflux disease, cancer of the lower esophagus, and aspiration-indu...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Vogt CD,Panoskaltsis-Mortari A

更新日期：2020-06-01 00:00:00

abstract：:Several techniques have been introduced to improve the pulp revascularization outcomes. The use of the tissue graft can create more practical tissue regeneration, provide vascular supply, and enhance tissue healing. The aim of the present study was to investigate the histologic and molecular outcomes of pulp revascula...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Khazaei S,Khademi A,Torabinejad M,Nasr Esfahani MH,Khazaei M,Razavi SM

更新日期：2020-09-01 00:00:00

abstract：:The authors previously created HAp or CaCO(3) formed on or in agarose gels (HAp and CaCO(3) gels, respectively) as biocompatible and biodegradable bone graft materials. However, these gels have limitations for bone regeneration. Mesenchymal stromal cells (MSCs) have osteogenic potential and are considered useful for b...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Mizuta N,Hattori K,Suzawa Y,Iwai S,Matsumoto T,Tadokoro M,Nakano T,Akashi M,Ohgushi H,Yura Y

更新日期：2013-01-01 00:00:00

abstract：:Postoperative mucosal regeneration of the middle ear cavity and the mastoid cavity is of great importance after middle ear surgery. However, the epithelialization of the mucosa in the middle ear is retarded because chronic inflammation without epithelialization aggravates gas exchange and clinical function. These envi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Hama T,Yamamoto K,Yaguchi Y,Murakami D,Sasaki H,Yamato M,Okano T,Kojima H

更新日期：2017-04-01 00:00:00

abstract：:The objective was to improve proliferation and chondrogenic potential of adipose stem cells (ASCs) by expansion on extracellular matrix (ECM) deposited by either ASCs or synovium-derived stem cells (SDSCs). ASCs isolated from porcine infrapatellar fat pad were separately expanded on conventional plastic flasks, ASC-de...

journal_title：Journal of tissue engineering and regenerative medicine

authors： He F,Pei M

更新日期：2013-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have been suggested as a potential cell source for tendon/ligament tissue engineering. Extrinsic cues, such as the chemical and physical properties of scaffolds, as well as external forces, play an important role in fibroblastic differentiation of these cells. In this study, we employed a...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Qiu Y,Lei J,Koob TJ,Temenoff JS

更新日期：2016-12-01 00:00:00

abstract：:This study aims to investigate the superiorities of fast degrading elastomeric poly(glycerol sebacate) (PGS)/polycaprolactone (PCL) grafts over autologous vein grafts in the reconstruction of carotid artery, thus providing more suitable vascular grafts for carotid artery replacement. We fabricated small arterial graft...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Yang X,Gao Z,Liu H,Wu W

更新日期：2019-07-01 00:00:00

abstract：:Regenerative medicine aims to replace lost cells and to restore damaged tissues and organs by either tissue-engineering approaches or stimulation of endogenous processes. Due to their biological properties, stem cells promise to be an effective source for such strategies. Especially adult multipotent stem cells (ASCs)...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Reinke S,Dienelt A,Blankenstein A,Duda GN,Geissler S

更新日期：2016-01-01 00:00:00

abstract：:Silk fibroin (SF) hydrogels can be obtained via self-assembly, but this process takes several days or weeks, being unfeasible to produce cell carrier hydrogels. In this work, a phospholipid, namely, 1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt (DMPG), was used to induce and accelerate the gelatio...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Laomeephol C,Guedes M,Ferreira H,Reis RL,Kanokpanont S,Damrongsakkul S,Neves NM

更新日期：2020-01-01 00:00:00

abstract：:Allogenic bone graft has been considered the gold standard in connection with bone graft material in revision joint arthroplasty. However, the lack of osteogenic potential and the risk of disease transmission are clinical challenges. The use of osteoinductive materials, such as demineralized bone matrix (DBM), alone o...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Babiker H,Ding M,Overgaard S

更新日期：2016-03-01 00:00:00

abstract：:In order to examine the differentiation potential of the tenocytes expanded in our defined culture medium (reported previously) and the effect of sequential combination of the two culture conditions on human tenocytes, a two-dimensional and three-dimensional experimental approach was used. Human tenocytes were sequent...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Qiu Y,Wang X,Zhang Y,Carr AJ,Zhu L,Xia Z,Sabokbar A

更新日期：2016-03-01 00:00:00