Immunoassay. Innovations in label technology.

abstract：CONTEXT:Within the continent of Africa few countries have been able to practice pathology at the levels present in Europe and the Americas, and pediatric pathology does not exist as a stand-alone specialty. The author was invited by a colleague from Harvard Medical School, Boston, Massachusetts, to join a group of Nort...

journal_title：Archives of pathology & laboratory medicine

authors： Kaschula RO

更新日期：2013-06-01 00:00:00

abstract：CONTEXT:Plasma cell myeloma and chronic lymphocytic leukemia are both common hematologic malignancies, sharing many epidemiologic features. Concomitant detection of the 2 conditions poses special diagnostic challenges for the pathologist. OBJECTIVE:To describe the pathologic findings in cases of concomitant bone marro...

journal_title：Archives of pathology & laboratory medicine

authors： Alley CL,Wang E,Dunphy CH,Gong JZ,Lu CM,Boswell EL,Burchette J,Lagoo AS

更新日期：2013-04-01 00:00:00

abstract：CONTEXT:We recently described a patient with chronic lymphocytic leukemia who presented with a breast carcinoma that stained positive for CD5 using a commercially available antibody (CD5-4C7, Novocastra, Newcastle upon Tyne, UK). OBJECTIVES:To study the distribution of CD5 immunoreactivity in tissue sections of a vari...

journal_title：Archives of pathology & laboratory medicine

authors： Walsh R,Peston D,Shousha S

更新日期：2001-06-01 00:00:00

abstract：CONTEXT:- At our medical center, cytopathologists perform rapid on-site evaluation for specimen adequacy of fine-needle aspiration and touch imprint of needle core biopsy lung cancer samples. Two years ago the molecular diagnostics laboratory at our institution changed to next-generation sequencing using the Ion Torren...

journal_title：Archives of pathology & laboratory medicine

authors： Padmanabhan V,Steinmetz HB,Rizzo EJ,Erskine AJ,Fairbank TL,de Abreu FB,Tsongalis GJ,Tafe LJ

更新日期：2017-03-01 00:00:00

abstract：:The emergence of the acquired immunodeficiency syndrome has wrought changes that have affected not only medicine and science, but many aspects of our social and political structures. In 1983 when it clearly became evident that acquired immunodeficiency syndrome could be transmitted by transfusions of blood components ...

journal_title：Archives of pathology & laboratory medicine

authors： Zuck TF

更新日期：1990-03-01 00:00:00

abstract：:von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by heterozygous mutations in the VHL tumor suppressor gene that is characterized by the occurrence of multiple endocrine and nonendocrine lesions. This review focuses on the endocrine manifestations of VHL disease. Pancreatic neuroendocrine proli...

journal_title：Archives of pathology & laboratory medicine

authors： Cassol C,Mete O

更新日期：2015-02-01 00:00:00

abstract：:Intracellular inclusions in lymphoproliferative disorders are not common. Multiple different types of inclusions have been reported in chronic lymphocytic leukemia (CLL), including vacuoles, crystals, and pseudocrystals. Most of the reported cases were seen in the bone marrow lymphocytes, and the majority of these on ...

journal_title：Archives of pathology & laboratory medicine

authors： Dorion RP,Shaw JH

更新日期：2003-05-01 00:00:00

abstract：CONTEXT:In Thailand until 2005 there had been no external quality assessment scheme at the national level for blood coagulation tests. Only a few laboratories had an external quality assessment for these tests. In the year 2005, the Thailand National External Quality Assessment Scheme for Blood Coagulation was founded....

journal_title：Archives of pathology & laboratory medicine

authors： Tientadakul P,Opartkiattikul N,Wongtiraporn W

更新日期：2009-01-01 00:00:00

abstract：:Canalicular adenomas are benign neoplasms that arise from salivary glands and often present as painless enlarging nodules. They have a predilection for upper lip but can be found throughout the oropharynx. To our knowledge, canalicular adenoma arising in the esophagus has never been described in the English literature...

journal_title：Archives of pathology & laboratory medicine

authors： Grimm EE,Rulyak SJ,Sekijima JH,Yeh MM

更新日期：2007-10-01 00:00:00

abstract：CONTEXT:Laboratory data are essential to the medical care of fetuses, infants, children, and adolescents. However, the performance and interpretation of laboratory tests on specimens from these patients, which may constitute a significant component of the workload in general hospitals and integrated health care systems...

journal_title：Archives of pathology & laboratory medicine

authors： Pysher TJ,Bach PR,Geaghan SM,Hamilton MS,Laposata M,Lockitch G,Brugnara C,Coffin CM,Pasquali M,Rinaldo P,Roberts WL,Rutledge JC,Ashwood ER,Blaylock RC,Campos JM,Goldsmith B,Jones PM,Lim M,Meikle AW,Perkins SL,Perr

更新日期：2006-07-01 00:00:00

abstract：:We studied a unique case of osteosarcoma of the testis. The tumor either originated from indifferent mesenchymal cells, or it represents a one-sided monomorphic development of a teratoma. ...

journal_title：Archives of pathology & laboratory medicine

authors： Mathew T,Prabhakaran K

更新日期：1981-01-01 00:00:00

abstract：:Spindle cell tumors arising in the lymph nodes are very rare. We report the light microscopic, histochemical, immunohistochemical, and ultrastructural findings of an unusual solitary spindle cell tumor in a peripheral lymph node of a 45-year-old woman. Microscopically, the tumor was characterized by interlacing fascic...

journal_title：Archives of pathology & laboratory medicine

authors： Lee JY,Abell E,Shevechik GJ

更新日期：1989-05-01 00:00:00

abstract：CONTEXT:Recent studies have uncovered a number of possible mechanisms by which prostate cancers can become resistant to systemic androgen deprivation, most involving androgen-independent reactivation of the androgen receptor. Genome-wide expression analysis with microarrays has identified a wide array of genes that are...

journal_title：Archives of pathology & laboratory medicine

authors： Mackinnon AC,Yan BC,Joseph LJ,Al-Ahmadie HA

更新日期：2009-07-01 00:00:00

abstract：CONTEXT:- Lobular carcinoma in situ (LCIS) refers to a neoplastic proliferation of cells that characteristically shows loss of E-cadherin expression and has long been regarded as a risk factor for invasive breast cancer. Long-term outcome studies and molecular data have also implicated LCIS as a nonobligate precursor t...

journal_title：Archives of pathology & laboratory medicine

authors： Ginter PS,D'Alfonso TM

更新日期：2017-12-01 00:00:00

abstract：:In three performance evaluation surveys, panels that consisted of human T-lymphotropic virus type I or type II (HTLV-I/II) antibody-positive and -negative plasma samples were mailed to laboratories that voluntarily participated in the Centers for Disease Control Model Performance Evaluation Program. Donor samples were...

journal_title：Archives of pathology & laboratory medicine

authors： Blumer SO,Hearn TL,Schalla WO,Cross GD,Valdiserri RO

更新日期：1992-05-01 00:00:00

abstract：:The Philadelphia (Ph) chromosome [der(22) t(9;22)(q34;q11)] is the characteristic chromosomal abnormality found in chronic myelogenous leukemia (CML). This chromosome has been reported in patients with other chromosomal abnormalities. In this study, we describe a patient with hematologically typical chronic-phase CML ...

journal_title：Archives of pathology & laboratory medicine

authors： Oudat R,Khan Z,Glassman AB

更新日期：2001-03-01 00:00:00

abstract：:A case of nongestational, extragonadal choriocarcinoma in a middle-aged man is described. Autopsy examination confirmed that the tumor originated in the lung. The trophoblastic origin of the tumor was documented by immunoperoxidase staining for human chorionic gonadotropin. ...

journal_title：Archives of pathology & laboratory medicine

authors： Sullivan LG

更新日期：1989-01-01 00:00:00

abstract：CONTEXT:The results of studies among patients with antithrombin deficiency have suggested that the use of warfarin will increase the level of antithrombin. OBJECTIVE:To reevaluate the effect of warfarin on antithrombin levels using an automated amidolytic method in current use. DESIGN:Antithrombin levels were measure...

journal_title：Archives of pathology & laboratory medicine

authors： Sanfelippo MJ,Engel JM,Onitilo AA

更新日期：2014-07-01 00:00:00

abstract：:Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized nonneoplastic vascular lesion of the spleen with fewer than 30 cases described. Microscopically, SANT consists of multiple well-circumscribed vascular/angiomatoid nodules showing plump endothelial cell and extravasated erythrocytes. The nodu...

journal_title：Archives of pathology & laboratory medicine

authors： Awamleh AA,Perez-Ordoñez B

更新日期：2007-06-01 00:00:00

abstract：:Nine pathologists from different institutions reviewed in a double-blind study 16 breast tumors previously indexed as typical medullary carcinoma, atypical medullary carcinoma, or infiltrative ductal carcinoma. A set of 16 slides was circulated two times among the nine pathologists. The diagnoses of typical and atypic...

journal_title：Archives of pathology & laboratory medicine

authors： Rigaud C,Theobald S,Noël P,Badreddine J,Barlier C,Delobelle A,Gentile A,Jacquemier J,Maisongrosse V,Peffault de Latour M

更新日期：1993-10-01 00:00:00

abstract：:Epithelioid sarcomas are rare, mesenchymal tumors of unknown histogenesis and display multidirectional differentiation, which is predominantly epithelial. They have no normal cellular counterpart and differ from both synovial sarcoma and carcinoma. They account for less than 1% of all soft tissue sarcomas and are usua...

journal_title：Archives of pathology & laboratory medicine

authors： Armah HB,Parwani AV

更新日期：2009-05-01 00:00:00

abstract：CONTEXT.—:There is an ongoing perception that the pathology job market is poor, which may be discouraging medical students from pursuing the specialty. Academic pathologists believe that jobs are available but relocation may be necessary. OBJECTIVE.—:To identify trends regarding the geographic relocation of pathologis...

journal_title：Archives of pathology & laboratory medicine

authors： George MR,Johnson KA,Gratzinger DA,Brissette MD,McCloskey CB,Conran RM,Dixon LR,Roberts CA,Rojiani AM,Shyu I,Timmons CF Jr,Hoffman RD

更新日期：2020-04-01 00:00:00

abstract：:Postmortem changes were studied by scanning electron microscopy (SEM) in renal tissue from five species of animals. Specimens were collected at intervals up to 24 hours after death. Six distinct morphological alterations were identified in the renal glomerulus, including capillary loop constriction, changes in microvi...

journal_title：Archives of pathology & laboratory medicine

authors： Langlinais PC

更新日期：1981-09-01 00:00:00

abstract：:The interrelationship between lymphocytes and hepatocytes was examined by light and electron microscopy, using epoxy-resin embedded thick and thin sections of biopsy liver tissues from patients with chronic persistent hepatitis (CPH) and chronic active liver disease (CALD). Close apposition of lymphocytes with hepatoc...

journal_title：Archives of pathology & laboratory medicine

authors： Kawanishi H

更新日期：1977-06-01 00:00:00

abstract：CONTEXT:A Treatise on Pathological Anatomy, published in 1829 by William E. Horner, is the first American textbook on pathology. Several articles have been written on Horner, but they do not evaluate the role that the knowledge he recorded played on the intellectual origin of the discipline of pathology in America. Onl...

journal_title：Archives of pathology & laboratory medicine

authors： Quinonez G,McLendon WW

更新日期：2011-12-01 00:00:00

abstract：:Adult rhabdomyoma is a benign, highly differentiated tumor of skeletal muscle. We observed transverse tubules and triads beside myofilaments in a rhabdomyoma from the submandibular area of a 66-year-old woman. Several types of muscle cells were present. In one, mitochondria abounded; in another, muscle filaments predo...

journal_title：Archives of pathology & laboratory medicine

authors： Warner TF,Goell W,Sundharadas M,Falk VS

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVES:Distinguishing intraductal papilloma from papillary carcinoma of the breast can be difficult using histologic criteria. Since cyclin D1, a G1 cell-cycle regulatory protein, is detectable immunohistochemically in a subset of breast carcinomas but not in benign breast tissues, we hypothesized that cyclin D1 im...

journal_title：Archives of pathology & laboratory medicine

authors： Saddik M,Lai R,Medeiros LJ,McCourty A,Brynes RK

更新日期：1999-02-01 00:00:00

abstract：:Basal cell carcinoma (BCC) is the most common form of skin cancer, accounting for 65% to 75% of all malignant skin tumors. Metastic BCC is very rare--only 109 documented cases have been reported to date. The mean time of survival after metastasis has been reported to be ten months. No effective therapeutic modality is...

journal_title：Archives of pathology & laboratory medicine

authors： Safai B,Good RA

更新日期：1977-06-01 00:00:00

abstract：CONTEXT:Cystatin C is becoming an increasingly popular biomarker for estimating glomerular filtration rate, and accurate measurements of cystatin C concentrations are necessary for accurate estimates of glomerular filtration rate. OBJECTIVE:To assess the accuracy of cystatin C concentration measurements in laboratorie...

journal_title：Archives of pathology & laboratory medicine

authors： Eckfeldt JH,Karger AB,Miller WG,Rynders GP,Inker LA

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:To establish the rates with which reference laboratories resolve inquiries telephoned to them from primary laboratories and to identify reference laboratory practices associated with higher rates of inquiry resolution. DESIGN AND PARTICIPANTS:For 2 months, or until 50 contacts had occurred, 545 primary labo...

journal_title：Archives of pathology & laboratory medicine

authors： Dale JC,Novis DA,Meier FA

更新日期：2001-05-01 00:00:00