Mechanisms of weight loss after gastric bypass and gastric banding.

Abstract:

:The obesity epidemic is a major health problem that is associated with increased morbidity and mortality. Gastrointestinal hormones have been increasingly understood to be an important element in appetite regulation. Several gastrointestinal hormones can contribute to obesity by modulating the activity of the gut-brain axis. Bariatric surgery is currently the most effective therapy for significant and sustained weight loss in morbidly obese patients. Understanding how gut hormones are altered by bariatric procedures has contributed to our understanding of the mechanisms of appetite. In this review, we address several gastrointestinal hormones that are associated with obesity and consider how their levels are altered after bariatric surgery. The review also addresses specific effects of different gut hormones on appetite, hunger, and energy balance.

journal_name

Obes Facts

journal_title

Obesity facts

authors

Bueter M,Ashrafian H,le Roux CW

doi

10.1159/000232383

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

325-31

issue

5

eissn

1662-4025

issn

1662-4033

pii

000232383

journal_volume

2

pub_type

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