High-Fat Diet Alters LH Secretion and Pulse Frequency in Female Mice in an Estrous Cycle-Dependent Manner.

abstract：:Testosterone propionate causes a striking increase in in vivo uptake of 2-deoxyglucose by the levator ani muscle of immature male rats. Autoradiography showed the labeled 2-deoxyglucose to be uniformly distributed over the entire muscle. Liquid scintillation counting of whole muscles allowed quantification of 2-deoxyg...

journal_title：Endocrinology

authors： Max SR,Toop J

更新日期：1983-07-01 00:00:00

abstract：:Oxytocin (OT) has a dual action in the uterus: a uterotonic action on myometrial cells and a prostaglandin (PG)-releasing action on endometrial/decidual cells. It had not been determined whether the OT-binding sites or receptors on the myometrial and the endometrial/decidual membranes are of the same type or may repre...

journal_title：Endocrinology

authors： Chan WY,Chen DL,Manning M

更新日期：1993-03-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP)-I has been reported to inhibit gastric acid secretion through stimulation of gastric somatostatin-14 (S-14) release. To establish whether some of the effects of CGRP-I on intestinal function might also be mediated through somatostatin, fetal rat intestinal cultures were treated w...

journal_title：Endocrinology

authors： Brubaker PL,Greenberg GR

更新日期：1993-12-01 00:00:00

abstract：:The possibility that chronic, multigenerational exposure to environmental estrogens selects for adaptive hormone-response phenotypes is a critical unanswered question. Embryos/larvae of killifish from an estrogenic-polluted environment (New Bedford Harbor, MA [NBH]) compared with those from a reference site overexpres...

journal_title：Endocrinology

authors： Cotter KA,Nacci D,Champlin D,Yeo AT,Gilmore TD,Callard GV

更新日期：2016-06-01 00:00:00

abstract：:Apoptosis is a physiological process by which multicellular organisms eliminate unwanted cells. Death factors such as Fas ligand induce apoptosis by triggering a series of intracellular protein-protein interactions mediated by defined motifs found in the signaling molecules. One of these motifs is the death effector d...

journal_title：Endocrinology

authors： Leo CP,Hsu SY,McGee EA,Salanova M,Hsueh AJ

更新日期：1998-12-01 00:00:00

abstract：:Male and female Wistar-Furth rats bearing the pituitary tumor MtT/W15 had serum GH and PRL levels several hundred-fold higher, and immunoreactive somatomedin levels 3-fold higher, than those of controls. The presence of tumor appeared to have no effect on specific binding of radioiodinated bovine GH to liver microsoma...

journal_title：Endocrinology

authors： Baxter RC,Zaltsman Z,Turtle JR

更新日期：1982-09-01 00:00:00

abstract：:Initiation of folliculogenesis through the induction of primordial follicle development in the ovary has an important role in determining the fertility and reproductive fitness of most mammalian species. The factors that control this critical process are largely unknown. The hypothesis tested in the current study was ...

journal_title：Endocrinology

authors： Parrott JA,Skinner MK

更新日期：1999-09-01 00:00:00

abstract：:Wortmannin (5-100 nM), a specific phosphatidyinositol 3-kinase inhibitor, augmented 8 mM glucose-induced insulin secretion from control Sprague Dawley rat islets in a dose-dependent manner. This effect persisted after its removal from the perifusion medium; however, this augmenting effect was reduced by the calcium ch...

journal_title：Endocrinology

authors： Zawalich WS,Zawalich KC

更新日期：2000-09-01 00:00:00

abstract：:We recently reported that fetal sheep corticotrophs (ACTH-producing cells) at 108 +/- 5 d (days) of gestation are relatively more responsive to CRH than to AVP, whereas those at 139 +/- 0 d (term = 145 d) and in the adult are more responsive to AVP. To further characterize these developmental changes, we used immunocy...

journal_title：Endocrinology

authors： Perez FM,Schwartz J,Rose JC

更新日期：1997-03-01 00:00:00

abstract：:Enlargement of the chimeric ventral prostate gland (VP) was induced by directly implanting either fetal urogenital sinus mesenchyme (UGM) or intact fetal urogenital sinus (UGS) into the VP of intact adult rats. The macromolecular content in the chimeric prostate increased from 40-100% (UGM implants) to 200-300% (UGS i...

journal_title：Endocrinology

authors： Thompson TC,Chung LW

更新日期：1986-06-01 00:00:00

abstract：:Leptin has been postulated to comprise part of an adipostat, whereby during states of excessive energy storage, elevated levels of the hormone prevent further weight gain by inhibiting appetite. A physiological role for leptin in this regard remains unclear because the presence of excessive food, and therefore the nee...

journal_title：Endocrinology

authors： Jeong KH,Sakihara S,Widmaier EP,Majzoub JA

更新日期：2004-07-01 00:00:00

abstract：:Although lower than in brain, the type 2 PTH receptor (PTH2-R) has been shown to be expressed throughout the cardiovascular system. Tuberoinfundibular peptide (TIP) purified from brain is thought to be the endogenous selective ligand of the PTH2-R. In the present studies, TIP and PTH2-R mRNA expressions were evidenced...

journal_title：Endocrinology

authors： Eichinger A,Fiaschi-Taesch N,Massfelder T,Fritsch S,Barthelmebs M,Helwig JJ

更新日期：2002-08-01 00:00:00

abstract：:The localization of calcitonin gene-related peptide (CGRP)-like immunoreactivity in the adrenal gland of the frog, Rana ridibunda, was examined by the indirect immunofluorescence technique. Using an antiserum directed against rat alpha-CGRP, the presence of a network of positive fibers was observed in the adrenal pare...

journal_title：Endocrinology

authors： Esneu M,Delarue C,Remy-Jouet I,Manzardo E,Fasolo A,Fournier A,Saint-Pierre S,Conlon JM,Vaudry H

更新日期：1994-07-01 00:00:00

abstract：:We have examined the regulation of adipogenesis of a 3T3-F442A cell variant. The variant, designated 3T3-GH-independent clone 16 (GI-16), was isolated after serum-induced adipogenic commitment. 3T3-GI-16 fibroblasts displayed a lower serum requirement for adipogenesis than the 3T3-F442A parent cell. Insulin-stimulated...

journal_title：Endocrinology

authors： Guller S,Sonenberg M,Corin RE

更新日期：1989-01-01 00:00:00

abstract：:Neuromedin-N (NN) and neurotensin (NT) were shown recently to be encoded in the same precursor molecule. Colocalization and corelease of ileal NT and NN have not yet been demonstrated and were investigated in the rat using antisera that separately recognized intact NT and NN in ileal extracts. Immunofluorescence label...

journal_title：Endocrinology

authors： Cuber JC,Herrmann C,Kitabgi P,Bosshard A,Bernard C,De Nadai F,Chayvialle JA

更新日期：1990-03-01 00:00:00

abstract：:The beta-subunit of hCG (hCG beta) displays immunological cross-reactivity with human LH (hLH). A detailed study was undertaken to investigate the effect of chemical and enzymatic modifications on the immunological behavior of hCG beta, particularly on its cross-reactivity with hLH, with a view to obtaining a highly h...

journal_title：Endocrinology

authors： Ghai RD,Mise T,Pandian MR,Bahl OP

更新日期：1980-11-01 00:00:00

abstract：:The recently discovered estrogen receptor-beta (ERbeta) is expressed in rodent and human testes. To obtain insight in the physiological role of ERbeta we have investigated the cell type-specific expression pattern of ERbeta messenger RNA (mRNA) and protein in the testis of rats of various ages by in situ hybridization...

journal_title：Endocrinology

authors： van Pelt AM,de Rooij DG,van der Burg B,van der Saag PT,Gustafsson JA,Kuiper GG

更新日期：1999-01-01 00:00:00

abstract：:The present experiments investigated the time course of maternal modulation of GH secretion and examined the possible role of milk in the regulation of GH secretion in neonatal rats. Serum GH concentrations in neonatal rats were high at birth and declined over time postpartum. Separation of rat pups from their mothers...

journal_title：Endocrinology

authors： Kacsoh B,Terry LC,Meyers JS,Crowley WR,Grosvenor CE

更新日期：1989-09-01 00:00:00

abstract：:The effect of amino acid substitutions introduced to the third alpha-helix in bovine GH (bGH) was investigated. A GH analog (bGH-M8), in which three amino acids were substituted to form an idealized amphiphilic alpha-helix, possessed the same specific binding affinity as wild-type bGH to cell membranes prepared from 3...

journal_title：Endocrinology

authors： Okada S,Chen WY,Wiehl P,Kelder B,Goodman HM,Guller S,Sonenberg M,Kopchick JJ

更新日期：1992-04-01 00:00:00

abstract：:Growth hormone-releasing factor-like immunoreactivity (GRF-LI) was detected in partially purified extracts of rat hypothalamus and duodenum with a highly specific RIA for rat GRF (rGRF). The concentration of rGRF-LI in the rat hypothalamus was 32.5 fmol/mg dry weight (455 fmol or 3.18 ng/region), while the rat duodenu...

journal_title：Endocrinology

authors： Bruhn TO,Mason RT,Vale WW

更新日期：1985-10-01 00:00:00

abstract：:The role of the paraventricular nucleus-dorsal anterior hypothalamus (PVN-DAHA) in the control of anterior pituitary gland secretion of FSH and LH in castrated male and female rats was examined. Bilateral radiofrequency lesions of the PVN-DAHA in chronically ovariectomized (OVX) rats lowered plasma FSH levels by 33% (...

journal_title：Endocrinology

authors： Lumpkin MD,McCann SM

更新日期：1984-12-01 00:00:00

abstract：:It is well established that endotoxemia disrupts reproductive capability, and several proinflammatory cytokines, especially IL-1 beta, IL-6, and TNF-alpha in the brain, have been implicated in this endocrine aberration. However, no previous study has directly compared the effects of the three major proinflammatory cyt...

journal_title：Endocrinology

authors： Watanobe H,Hayakawa Y

更新日期：2003-11-01 00:00:00

abstract：:The expression of short-chain fatty acid receptors GPR41/FFAR3 and GPR43/ free fatty acid receptor 2 (FFAR2) was studied in the gastrointestinal tract of transgenic monomeric red fluorescent protein (mRFP) reporter mice. In the stomach free fatty acid receptor 3 (FFAR3)-mRFP was expressed in a subpopulation of ghrelin...

journal_title：Endocrinology

authors： Nøhr MK,Pedersen MH,Gille A,Egerod KL,Engelstoft MS,Husted AS,Sichlau RM,Grunddal KV,Poulsen SS,Han S,Jones RM,Offermanns S,Schwartz TW

更新日期：2013-10-01 00:00:00

abstract：:Using a primary culture of neonatal rat heart, we investigated the properties of iodothyronine 5'-deiodinating activity in the heart. 125I- release from [125I] reverse T3 incubated with cell homogenates depended on the concentrations of protein and dithiothreitol, pH, incubation time, and temperature of the incubation...

journal_title：Endocrinology

authors： Mori Y,Nishikawa M,Toyoda N,Yonemoto T,Matsubara H,Inada M

更新日期：1991-06-01 00:00:00

abstract：:A RIA for mouse placental lactogen-I (mPL-I) was developed using recombinant mPL-I as the standard, radioligand, and antigen for antiserum production. Displacement curves for dilutions of serum and placental extracts from pregnant mice were parallel to the recombinant mPL-I standard curve. Serum from male and nonpregn...

journal_title：Endocrinology

authors： Ogren L,Southard JN,Colosi P,Linzer DI,Talamantes F

更新日期：1989-11-01 00:00:00

abstract：:Thyroid hormone (T(3)) regulates growth, development, and differentiation. These activities are mediated by the nuclear thyroid hormone receptors (TRs), which belong to the steroid/TR superfamily of ligand-dependent transcription factors. The effect of T(3) treatment on target gene regulation was investigated in a TRa...

journal_title：Endocrinology

authors： Shih CH,Chen SL,Yen CC,Huang YH,Chen CD,Lee YS,Lin KH

更新日期：2004-06-01 00:00:00

abstract：:Potassium deficiency produced by feeding mice a low potassium diet caused a marked decrease in plasma and testicular testosterone concentrations and a concomitant fall in the weight of seminal vesicles and in renal ornithine decarboxylase activity. All of these parameters were rapidly restored when potassium supply wa...

journal_title：Endocrinology

authors： Sánchez-Capelo A,Castells MT,Cremades A,Peñafiel R

更新日期：1996-09-01 00:00:00

abstract：:Macrophages are known to release a lipophilic factor that stimulates testosterone production by Leydig cells. This macrophage-derived factor (MDF) is thought to be physiologically relevant, because removal of macrophages from the testis results in altered testosterone secretion and reduced fertility. The purpose of th...

journal_title：Endocrinology

authors： Nes WD,Lukyanenko YO,Jia ZH,Quideau S,Howald WN,Pratum TK,West RR,Hutson JC

更新日期：2000-03-01 00:00:00

abstract：:The effect of fibroblast growth factor (FGF) on LH-stimulated testosterone production was investigated using primary cultures of rat testicular cells. Testicular cells obtained from neonatal rats (8-9 days of age) were maintained in culture for 3 days and then challenged with LH with or without basic FGF. After 3 addi...

journal_title：Endocrinology

authors： Fauser BC,Baird A,Hsueh AJ

更新日期：1988-12-01 00:00:00

abstract：:Hypoglycemia associated with diabetes management is a potential risk for cardiovascular diseases. However, the effect of hypoglycemic episodes including a surge of sympathetic activity on the progression of neointima formation after vascular injury remains largely unknown. In this study, insulin was injected intraperi...

journal_title：Endocrinology

authors： Yasunari E,Mita T,Osonoi Y,Azuma K,Goto H,Ohmura C,Kanazawa A,Kawamori R,Fujitani Y,Watada H

更新日期：2014-06-01 00:00:00