Abstract：
OBJECTIVE:To determine the prevalence of the metabolic syndrome postpartum in women with a history of pregnancy complicated by early-onset vascular disorders compared with women with late-onset disorders. METHODS:In this retrospective cohort study 849 women with a history of pregnancy complicated by vascular disorders (preeclampsia; gestational hypertension; hemolysis, elevated liver enzymes, low platelets syndrome; eclampsia; placental abruption; fetal growth restriction; and stillbirth as a result of placental insufficiency) were divided into early-onset (delivery before 32 weeks of gestation, n=376) and late-onset (delivery at or beyond 32 weeks, n=473). By use of four internationally accepted criteria to diagnose metabolic syndrome, we compared its prevalence in both groups using odds ratios (ORs), adjusted for maternal age, smoking, alcohol and coffee consumption, birth weight centile, stillbirth, and interval between delivery and measurements. RESULTS:The metabolic syndrome was present in 15-25% of women after early-onset vascular-complicated pregnancy and in 10-14% of women after late-onset disease, depending on the criteria set used; adjusted OR 2.51 (95% confidence interval [CI] 1.66-3.80) using World Health Organization criteria; adjusted OR 2.01 (95% CI 1.37-2.96) using International Diabetes Federation criteria; adjusted OR 2.16 (95% CI 1.31-3.55) using Third Adult Treatment Panel (ATPIII) criteria; and adjusted OR 2.02 (95% CI 1.28-3.17) using Third Adult Treatment Panel updated criteria. CONCLUSION:The prevalence of the metabolic syndrome postpartum is twice as high in women with a history of early-onset (delivery before 32 weeks) compared to late-onset vascular-complicated pregnancy (delivery at or beyond 32 weeks). LEVEL OF EVIDENCE:II.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Stekkinger E,Zandstra M,Peeters LLH,Spaanderman MEAdoi
10.1097/AOG.0b013e3181b7b242subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1076-1084issue
5eissn
0029-7844issn
1873-233Xpii
00006250-200911000-00018journal_volume
114pub_type
杂志文章abstract：:In an ongoing clinical trial, 100 patients with an unruptured ectopic pregnancy of 3.5 cm or less in greatest dimension were treated with an outpatient protocol of methotrexate and citrovorum factor chemotherapy. Methotrexate and citrovorum were given on alternating days until the hCG titer had decreased by 15% on 2 c...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:This article, for the "To the Point" series prepared by the Association of Professors of Gynecology and Obstetrics Undergraduate Medical Education Committee, supplies educators with a review of best practices regarding incorporation of the electronic medical record (EMR) into undergraduate medical education. The uniqu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1097/AOG.0000000000001004
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To assess the changes in the subpopulations of lymphocytes and in lymphocyte mitogenic activity in women with endometriosis receiving GnRH-agonist treatment. METHODS:Twenty-six women with advanced endometriosis from the National Cheng Kung University Medical College were studied. Each received a total of six...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/s0029-7844(97)00145-2
更新日期：1997-06-01 00:00:00
abstract：:Several authorities have recommended cesarean section for all intrapartum breech presentations. The present study documents that judiciously selected fetuses at term in breech presentation may be safely delivered vaginally by a selective management protocol that requires cesarean section when mandated criteria are not...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:Double aneuploidies account for 0.21-2.8% of spontaneous abortions resulting from chromosomal abnormalities. Rarely, cell-free DNA testing detects multiple aneuploidies; however, to discern among maternal, placental, and fetal origin, further evaluation is required. CASE:A 49-year-old woman, gravida 5 para ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001390
更新日期：2016-06-01 00:00:00
abstract：:Seizure disorders frequently are diagnosed and managed during adolescence; therefore, obstetrician-gynecologists who care for adolescents should be familiar with epilepsy and other seizure disorders, as well as antiepileptic drugs. Patients diagnosed with seizure disorders during childhood may have increased seizure a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003828
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:Women with a history of preeclampsia have an increased risk of developing chronic hypertension and cardiovascular disease. However, little is known about the mechanism responsible for vascular disease in formerly preeclamptic women. The aim of our study was to test whether preeclampsia predisposes to central ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31819caf0f
更新日期：2009-04-01 00:00:00
abstract：:A review of 540 patients evaluated by the Gynecologic Colposcopy Clinic for abnormal cervical cytology revealed that 372 (68.9%) had cervical intraepithelial neoplasia (CIN), microinvasive carcinoma, or frank invasive carcinoma. The repeat cytologic smear taken before biopsy was falsely negative in 26.4%. An endocervi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198309000-00016
更新日期：1983-09-01 00:00:00
abstract：OBJECTIVE:To test the hypothesis that increasing the intravenous fluid bolus volume at the time of epidural placement in women with narrow pulse pressure would reduce postepidural fetal heart rate (FHR) abnormalities, hypotension, and resuscitative obstetric interventions. METHODS:We performed a single-center randomiz...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/AOG.0000000000002326
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:To estimate the occurrence of synchronous epithelial ovarian and endometrial cancers among ovarian cancer patients and to assess survival of women with synchronous cancers. METHODS:Synchronous ovarian and endometrial cases were identified using data from the Surveillance, Epidemiology, and End Results Progra...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31819c7bdf
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:Neonatal alloimmune thrombocytopenia is caused by platelet antigen incompatibility between the mother and fetus. Affected fetuses may have severe thrombocytopenia leading to intracranial hemorrhage before or at birth. We sought to treat this condition in utero to prevent these hemorrhages. METHODS:Eighteen w...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:Danazol is widely used in the management of endometriosis and mammary dysplasia. However, its mechanism of action is still obscure because of the few studies done and the controversial results obtained. Antigonadotropic activity has been postulated by some investigators, whereas others have observed no effect on the g...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：:Two hundred thirteen women with abnormal glucose tolerance tests (GTTs) were diagnosed over 9 years by a screening program involving the total antenatal population. Each subject was matched for age, parity, and ethnic group with a control. The gestational diabetics were subdivided into classes A1 or A2 based on the fa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:To test the performance characteristics of a new DNA probe designed for the rapid identification of heavy colonization of the genital tract with group B streptococci. METHODS:Vaginal and combined vaginal-perianal samples were collected from 193 pregnant women and cultured on colistin-nalidixic acid agar plat...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/0029-7844(95)00199-2
更新日期：1995-10-01 00:00:00
abstract：:When any fetal blood group factor inherited from the father is not possessed by the mother, antepartum or intrapartum fetal-maternal bleeding may stimulate an immune reaction in the mother Maternal immune reactions also can occur from blood product transfusion. The formation of maternal antibodies, or"alloimmunization...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/00006250-200608000-00044
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to estimate the probability of spontaneous delivery at 34 weeks or less according to cervical assessment by transvaginal scan associated with previous obstetric history. METHODS:Ultrasound transvaginal cervical length and presence of funneling were evaluated in 1,958 singleton pregn...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000154157.22500.1d
更新日期：2005-03-01 00:00:00
abstract：:Infertility is a disease that affects up to 15.5% of reproductive-aged couples. Until the birth of the first neonate born from in vitro fertilization (IVF) in 1978, many infertile couples did not have an opportunity to conceive a biological child. Over the past 40 years, access to and effectiveness of IVF have increas...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1097/AOG.0000000000002786
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Goodpasture syndrome, an immunologic disorder characterized by glomerulonephritis and pulmonary hemorrhage, rarely presents in pregnancy. CASE:We describe a patient who was diagnosed with Goodpasture syndrome in her second trimester. She required daily hemodialysis, intermittent plasmapheresis, and immunosu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000161061.35611.98
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of group B streptococci (GBS) colonization in a subsequent pregnancy in women with and without GBS colonization in an index pregnancy. METHODS:A retrospective cohort study of women who had two consecutive deliveries with the availability of GBS culture result at 35 to 37 weeks of g...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31817f5cb9
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVE:To analyze the relation between tensile strength and levels of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2 at a number of sites in human fetal membranes. METHODS:Tensile strengths of fetal membranes from five women who delivered vaginally a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)00811-5
更新日期：2000-06-01 00:00:00
abstract：:The ACOG has recommended that the initial visit to an obstetrician-gynecologist for health guidance, screening, and provision of preventive services should take place around age 13-15. At this visit, clinicians can provide guidance to young girls and their parents on adolescent physical development based on data that ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0029-7844(02)01660-5
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:To test the hypothesis that fetal growth restriction (FGR) associated with a maternal hypertensive disorder results in worse perinatal outcome than FGR in pregnancies without maternal hypertension. METHODS:All consecutive, singleton, nondiabetic, small for gestational age (SGA) deliveries (birth weight at or...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(96)02169-2
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVES:Use of prostaglandins, including sulprostone (an E2 analog), is recommended for second-line uterotonic treatment of atonic postpartum hemorrhage and might be considered as an indicator of quality of care in severe atonic postpartum hemorrhage management. Our objective was to estimate whether sulprostone was ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1097/AOG.0b013e3182255335
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:To assess the association between cytokines in the amniotic fluid (AF) and preterm delivery, the isolation of bacteria from the AF or chorioamnion, and histologic chorioamnionitis. METHODS:Fifty afebrile women with intact membranes in preterm labor at or before 34 weeks' gestation underwent amniocentesis. Cy...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:To determine whether preoperative ketoprofen and mesosalpinx infiltration, either alone or in combination, favorably influence postoperative recovery after outpatient laparoscopic sterilization. METHODS:In a double-blind, randomized, placebo-controlled study, 20 women received 100 mg of oral ketoprofen preop...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(96)00222-0
更新日期：1996-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of an outcomes-management program designed to provide high-quality patient care, generate data for outcomes research, and decrease costs in a managed-care environment. METHODS:An outcomes-management program was launched in June 1994, based on the elimination of wasteful or ineff...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/S0029-7844(97)00008-2
更新日期：1997-04-01 00:00:00
abstract：BACKGROUND:To reorganize reusable laparoscopic instrumentation to promote instrument accessibility, minimize instrument breakage, eliminate infrequently used instruments on permanent trays, and help control maintenance costs. TECHNIQUE:The Robert Wood Johnson University Hospital Gynecologic Steering Committee evaluate...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:A multicenter, randomized placebo-controlled trial among women with singleton pregnancies and a history of spontaneous preterm birth found that weekly injections of 17 alpha-hydroxyprogesterone caproate (17P), initiated between 16 and 20 weeks of gestation, reduced preterm birth by 33%. The current study esti...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1097/01.AOG.0000150560.24297.4f
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:To describe a second-stage partogram based on a system of scoring the descent and position of the fetal head and to use this system for studying progress in the second stage of labor and predicting mode of delivery and obstetric outcome. METHODS:A prospective observational study of 1413 women at term with a ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)00981-9
更新日期：2000-11-01 00:00:00
abstract：:The healing of a midfibular fracture was studied in mature rats. The strength of the healing fracture was determined by a constant speed-driven tensiometer which measured the force required to separate the healing callus. The breaking strength of the healing experimental fracture was ascertained in control, estrogen-t...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
