Circadian rhythm in negative affect: Implications for mood disorders.

Abstract:

:In humans, there is an endogenous, near 24-h (i.e., circadian) variation in mood with the best mood occurring during the circadian day and the worst mood occurring during the circadian night. Only positive affect, and not negative affect, has been shown to contribute to this circadian rhythm. We discovered a sharp circadian peak in negative affect during the circadian night coincident with a circadian trough in positive affect. These findings may help explain the association of depression with insomnia, the increased risk of suicide with nocturnal wakefulness, and the correlation between circadian misalignment and symptom severity in Major Depressive Disorder.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Emens JS,Berman AM,Thosar SS,Butler MP,Roberts SA,Clemons NA,Herzig MX,McHill AW,Morimoto M,Bowles NP,Shea SA

doi

10.1016/j.psychres.2020.113337

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

113337

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(20)30206-7

journal_volume

293

pub_type

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