Gastric Biopsies in Gastroparesis: Insights into Gastric Neuromuscular Disorders to Aid Treatment.

abstract：:Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients....

journal_title：Gastroenterology clinics of North America

authors： Fontana RJ,Watkins PB

更新日期：1995-12-01 00:00:00

abstract：:QOL assessment in oncology has made great strides in recent years. There was a difficult time initially, during which QOL tools were "thrown in" to many clinical trials as an afterthought, without a pre-specified scientific question. As expected from such a scattershot approach, the results were underwhelming and disa...

journal_title：Gastroenterology clinics of North America

authors： Hassan I,Cima RC,Sloan JA

更新日期：2006-03-01 00:00:00

abstract：:Gastroparesis is a heterogeneous disorder defined by delay in gastric emptying. Symptoms of gastroparesis are nonspecific, including nausea, vomiting, early satiety, bloating, and/or abdominal pain. Normal gastric motor function and sensory function depend on a complex coordination between the enteric and central nerv...

journal_title：Gastroenterology clinics of North America

authors： Nguyen LA,Snape WJ Jr

更新日期：2015-03-01 00:00:00

abstract：:Constipation and diarrhea are common during pregnancy, occurring in up to one-third of women. Constipation is often the result of physiologic changes that occur during pregnancy, usually from hormonal effects on gastrointestinal motility. Diarrhea, on the other hand, is often caused by the same disorders responsible f...

journal_title：Gastroenterology clinics of North America

authors： Bonapace ES Jr,Fisher RS

更新日期：1998-03-01 00:00:00

abstract：:In the treatment of arthritis, NSAIDs are some of the most commonly used drugs, although the prescription of such drugs has been questioned due to their inherent risks for gastrointestinal compromise, platelet effects, and the potential for renal toxicity with long-term use. With the availability of celecoxib and rofe...

journal_title：Gastroenterology clinics of North America

authors： Simon LS

更新日期：2001-12-01 00:00:00

abstract：:Studies of ontogenesis contribute to better understanding of regulatory events underlying the striking heterogeneity in B-cell differentiation pathways employed in the human mucosal immune system. This disparity is probably explained by exogenous environmental factors, although regional differences probably also exist...

journal_title：Gastroenterology clinics of North America

authors： Brandtzaeg P,Nilssen DE,Rognum TO,Thrane PS

更新日期：1991-09-01 00:00:00

abstract：:The management of recurrent, symptomatic malignant ascites can be problematic for physicians and patients. The most common, low-risk method is large-volume paracentesis. Patient disease progression often leads to rapid reaccumulation of ascites, which requires frequent return visits to the hospital for symptom managem...

journal_title：Gastroenterology clinics of North America

authors： Rosenberg SM

更新日期：2006-03-01 00:00:00

abstract：:New high-resolution colonoscopes and filter technologies are allowing us to visualize more lesions and better characterize lesions within the gastrointestinal tract. In light of recent findings that flat and serrated lesions are more likely to contain invasive cancer and that even small lesions (5-10 mm) may contain a...

journal_title：Gastroenterology clinics of North America

authors： Sauk J,Hoffman A,Anandasabapathy S,Kiesslich R

更新日期：2010-12-01 00:00:00

abstract：:Three (author's standard) or five biopsy specimens (two antral, two corpus, one incisura) as suggested by the Sydney system (original and revised version) [figure: see text] correctly separate infected mucosa from uninfected mucosa. No combination identified correctly the presence of intestinal metaplasia to be consid...

journal_title：Gastroenterology clinics of North America

authors： el-Zimaity HM

更新日期：2000-12-01 00:00:00

abstract：:Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence. The pathophysiology of diarrhea in these diseases is complex, but defective absorption of salt and water by the inflamed bowel is the most important mechanism involved. In add...

journal_title：Gastroenterology clinics of North America

authors： Wenzl HH

更新日期：2012-09-01 00:00:00

abstract：:Barrett's esophagus, currently defined as endoscopically apparent columnar metaplasia of the esophagus with histologic documentation of goblet cells, is the precursor to esophageal adenocarcinoma. However, not all patients with this disorder require intensive surveillance. Pathologic diagnosis and grading of dysplasia...

journal_title：Gastroenterology clinics of North America

authors： Hornick JL,Odze RD

更新日期：2007-12-01 00:00:00

abstract：:Gallstones are common with prevalences as high as 60% to 70% in American Indians and 10% to 15% in white adults of developed countries. Ethnic differences abound with a reduced frequency in black Americans and those from East Asia, while being rare in sub-Saharan Africa. Certain risk factors for gallstones are immutab...

journal_title：Gastroenterology clinics of North America

authors： Stinton LM,Myers RP,Shaffer EA

更新日期：2010-06-01 00:00:00

abstract：:If one reviews the literature with zeal, it is increasingly apparent that few organs escape recruitment when IBD is chronic or progressive. Insights into mucosal pathophysiology have helped with understanding the more frequent extraintestinal manifestations, but the mechanisms attendant to the development of less comm...

journal_title：Gastroenterology clinics of North America

authors： Levine JB,Lukawski-Trubish D

更新日期：1995-09-01 00:00:00

abstract：:Common disease states in gastroenterology are more effectively treated in an obese patient when weight loss is incorporated into the treatment plan. Strategies that seek to achieve weight loss improve outcomes in the treatment of hepatitis C, non-alcoholic fatty liver disease, and colorectal cancer, as examples. Pharm...

journal_title：Gastroenterology clinics of North America

authors： Keith JN

更新日期：2016-12-01 00:00:00

abstract：:Adenomatous polyps are the benign precursors of colorectal adenocarcinoma. Colonic adenomas occur commonly in adults in Western countries. There is recent evidence that inheritance may play an important role in the etiology of these adenomatous polyps. Colonic adenomatous polyposis (numerous colonic adenomas) is the c...

journal_title：Gastroenterology clinics of North America

authors： Burt RW,Samowitz WS

更新日期：1988-12-01 00:00:00

abstract：:This article reviews the role of therapeutic endoscopy in the diagnosis and treatment of nonvariceal upper and lower gastrointestinal (GI) hemorrhage. The initial approach to patients with GI bleeding is reviewed. Endoscopic treatment of various stigmata of recent peptic ulcer hemorrhage is discussed in detail. Manage...

journal_title：Gastroenterology clinics of North America

authors： Savides TJ,Jensen DM

更新日期：2000-06-01 00:00:00

abstract：:A variety of infectious enteric pathogens (bacterial, viral, and protozoal) can lead to a systemic diarrheal illness in international travelers traveling from industrialized countries to developing areas of the world. Many of the agents that lead to this syndrome have been identified, and their mode of transmission ha...

journal_title：Gastroenterology clinics of North America

authors： Chak A,Banwell JG

更新日期：1993-09-01 00:00:00

abstract：:This article highlights the different dietary approaches that have evolved and become popular over the past few years. Whether these are fads or truly represent important changes in the way peo-ple eat and that ultimately will lead to a lower rate of obesity and improved health is impossible to know. ...

journal_title：Gastroenterology clinics of North America

authors： Balart LA

更新日期：2005-03-01 00:00:00

abstract：:Barium radiography of the gastrointestinal tract in patients with AIDS can assist in the evaluation of numerous problems including dysphagia, odynophagia, diarrhea, abdominal pain, symptoms of intermittent obstruction, and/or gastrointestinal bleeding. It can localize disease, evaluate complications, guide endoscopic ...

journal_title：Gastroenterology clinics of North America

authors： Wall SD

更新日期：1988-09-01 00:00:00

abstract：:Nutritional support can improve the outcome from severe acute pancreatitis in two ways: first by providing the building blocks for tissue repair and recovery, and second, by modulating the inflammatory response and preventing organ failure, both of which are responsible for most of the morbidity and mortality associat...

journal_title：Gastroenterology clinics of North America

authors： O'Keefe SJ,Sharma S

更新日期：2007-06-01 00:00:00

abstract：:Chronic HIV-associated diarrhea is currently a field in flux. Improved noninvasive diagnostic tests, improved pathogen-specific regimens, and better empiric therapies may change some of the assumptions used to select algorithms for diagnostic evaluation and management. Any shift in the cause of diarrhea from pathogen-...

journal_title：Gastroenterology clinics of North America

authors： Cohen J,West AB,Bini EJ

更新日期：2001-09-01 00:00:00

abstract：:Pediatric pancreatitis is an emerging field with an increasing incidence of disease. Management of pediatric pancreatitis is understudied and, therefore, extrapolated from adult studies (although the etiologies are different). There is evidence that feeding is safe in mild acute pancreatitis in children without increa...

journal_title：Gastroenterology clinics of North America

authors： Abu-El-Haija M,Lowe ME

更新日期：2018-12-01 00:00:00

abstract：:A better definition of a pseudocyst that clearly separates it from acute fluid collection, improvements in imaging studies, and a better understanding of the natural history of pseudocysts have changed the concepts regarding their management. The old teaching that cysts of more than 6 cm in diameter that have been pre...

journal_title：Gastroenterology clinics of North America

authors： Pitchumoni CS,Agarwal N

更新日期：1999-09-01 00:00:00

abstract：:The explanation as to why gastroesophageal reflux disease develops remains unanswered. We have learned much about the regulation of LES pressure, the single most important factor in the development of reflux disease. Our understanding of factors involved in the clearance of refluxed contents has also increased. The pr...

journal_title：Gastroenterology clinics of North America

authors： Ogorek CP,Cohen S

更新日期：1989-06-01 00:00:00

abstract：:As the AIDS epidemic continues to grow, it becomes increasingly important that physicians are aware of the gastrointestinal and abdominal diseases specific to this group of patients. Most AIDS patients exhibit gastrointestinal symptoms at some time during the course of their disease. Clinical AIDS is often determined ...

journal_title：Gastroenterology clinics of North America

authors： Yee J,Wall SD

更新日期：1995-06-01 00:00:00

abstract：:BA is a rare disease of unclear etiology; nevertheless, its impact in the field of pediatric hepatology is significant. It is the most common surgically correctable cause of neonatal cholestasis and is the most common pediatric disease referred for liver transplantation. Little progress has been made with regard to im...

journal_title：Gastroenterology clinics of North America

authors： Haber BA,Russo P

更新日期：2003-09-01 00:00:00

abstract：:This article has reviewed the morphologic features of BE and its complications of dysplasia and adenocarcinoma in routinely processed endoscopic biopsy and resection specimens. In addition, the problems related to the diagnosis of dysplasia in tissue samples have been analyzed, and the role of esophageal brush cytolog...

journal_title：Gastroenterology clinics of North America

authors： Antonioli DA,Wang HH

更新日期：1997-09-01 00:00:00

abstract：:High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux disease (GERD) and esophageal peristaltic performance are ...

journal_title：Gastroenterology clinics of North America

authors： Mello M,Gyawali CP

更新日期：2014-03-01 00:00:00

abstract：:In patients with Crohn's disease on biologic medications, the use of therapeutic drug monitoring leads to a personalized approach to optimize treatment. Using an algorithmic approach, measurement of drug concentrations and anti-drug antibodies can be used to improve treatment outcomes. Therapeutic drug concentrations ...

journal_title：Gastroenterology clinics of North America

authors： Heron V,Afif W

更新日期：2017-09-01 00:00:00

abstract：:This article examines the transitions in pharmacological therapy for obesity. It reviews the current options approved by the Food and Drug Administration and several drugs approved for other indications that can be used to treat obesity as well. Because weight regulation is complex and redundant systems protect agains...

journal_title：Gastroenterology clinics of North America

authors： Kaplan LM

更新日期：2010-03-01 00:00:00