Abstract:
PURPOSE:Propolis (bee glue) is a resinous mixture of different plant exudates that possesses a wide range of biological and antimicrobial activities and has been used as a food supplement and in complementary medicine for centuries. Some researchers have proposed that propolis could be a potential curative compound against microbial agents such as protozoan parasitic infections by different and occasionally unknown mechanisms due to the immunoregulatory function and antioxidant capacity of this natural product. METHODS:In this review, we concentrate on in vitro and in vivo anti-protozoan activities of propolis extracts/fractions in the published literature. RESULTS:In Leishmania, propolis inhibits the proliferation of promastigotes and produces an anti-inflammatory effect via the inhibition of nitric oxide (NO) production. In addition, it increases macrophage activation, TLR-2, TNF-α, IL-4, IL-17 production, and downregulation of IL-12. In Plasmodium and Trypanosoma, propolis inhibits the parasitemia, improving anemia and increasing the IFN-γ, TNF-α, and GM-CSF cytokines levels, most likely due to its strong immunomodulatory activity. Moreover, propolis extract arrests proliferation of T. cruzi, because it has aromatic acids and flavonoids. In toxoplasmosis, propolis increases the specific IgM and IgG titers via decreasing the serum IFN-γ, IL-1, and IL-6 cytokines levels in the rats infected with T. gondii. In Cryptosporidium and Giardia, it decreases oocysts shedding due to phytochemical constituents, particularly phenolic compounds, and increases the number of goblet cells. Propolis inhibits the growth of Blastocystis, possibly by apoptotic mechanisms like metronidazole. Unfortunately, the mechanism action of propolis' anti-Trichomonas and anti-Acanthamoeba is not well-known yet. CONCLUSION:Reviewing the related literature could highlight promising antimicrobial activities of propolis against intracellular and extracellular protozoan parasites; this could shed light on the exploration of more effective drugs for the treatment of protozoan parasitic infections in the near future.
journal_name
Acta Parasitoljournal_title
Acta parasitologicaauthors
Asfaram S,Fakhar M,Keighobadi M,Akhtari Jdoi
10.1007/s11686-020-00254-7subject
Has Abstractpub_date
2020-07-20 00:00:00eissn
1230-2821issn
1896-1851pii
10.1007/s11686-020-00254-7pub_type
杂志文章,评审abstract::Ancylostoma ceylanicum belongs to a group of soil-transmitted helminths, which infect almost 576 mln people worldwide and are a major cause of anaemia and malnutrition. Upon contact with a permissive host, third-stage larvae (L3) residing in the environment become activated larvae (ssL3), a process associated with cha...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-013-0116-z
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To seek for the optimal immunization procedure of DNA vaccine pVAX1-pEtK2-IL-2 which was produced via cloning pEtK2 antigen gene of Eimeria tenella (E. tenella) and chicken IL-2 (chIL-2) gene into expression vector pVAX1. METHODS:The doses, routes, times of inoculation and ages of the first inoculation of chic...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00090-4
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Sri Lanka is endemic to cutaneous leishmaniasis and reported as the latest focus of leishmaniasis in the Asian subcontinent. Annually, the number of leishmaniasis cases is increasing; therefore, more efficient diagnostic tools, treatment methods and effective prevention measures are indispensable. For this reas...
journal_title:Acta parasitologica
pub_type: 杂志文章,评审
doi:10.2478/s11686-020-00174-6
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Fish parasites can cause diseases in humans and lead to commercial losses in fisheries and aquaculture. The objectives of this study were to analyze E. ongus's parasite fauna regarding food safety and parasite transmission risk between Epinephelus species and test whether E.ongus populations can be distinguishe...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1007/s11686-020-00312-0
更新日期:2020-12-14 00:00:00
abstract::A new isosporoid coccidian species (Protozoa: Apicomplexa: Eimeriidae) is reported from the southern house wren Troglodytes musculus, a very well distributed species in South and Central America. Isospora corruirae sp. nov. oocysts are subspherical to ovoidal, 24.1 × 21.4 μm, with smooth, bilayered wall. Micropyle and...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2016-0057
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:Larval stages of trombiculid mites infest a wide variety of wild and domestic animals. The most common clinical signs related with the presence of these parasites are alopecia, crusts, erythema, excoriation, erosion, papules, pustules and vesicles. Most of trombiculid infestations may not be perceived by the cl...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1007/s11686-020-00247-6
更新日期:2020-07-15 00:00:00
abstract:INTRODUCTION:Haemaphysalis longicornis is an important ectoparasite of domestic and wild animals that can transmit many pathogens including viruses, fungi, bacteria and protozoa. MATERIALS AND METHODS:In this study, we examined genetic variation and population genetics in three mitochondrial (mt) genes [cox1 (cytochro...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00053-9
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To describe a new genus and a new species of an ectoparasitic ergasilid (Copepoda, Ergasilidae) parasite of the red-tailed lambari, Astyanax fasciatus, from Jurumirim Reservoir (Upper Paranapanema River), São Paulo State, Brazil. METHODS:The host fish were collected using multi-panel gill nets. The gill of eac...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00108-x
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the in vitro and in vivo efficacy of propolis against Ligictaluridus floridanus on Ictalurus punctatus gills. METHODS:This study used an ethanol extract of propolis at a concentration of 300 mg mL-1, with a total polyphenol concentration of 2.77 mg mL-1 as determined by ch...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-020-00218-x
更新日期:2020-09-01 00:00:00
abstract::This study describes development and evaluation of a multiplex PCR assay for simultaneous detection of Theileria annulata, Babesia bigemina and Anaplasma marginale infections in bovines. The assay was developed using parasites specific genomic DNA and three sets of PCR primers targeting the Tams1, 18S rRNA and 16S rRN...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0090
更新日期:2018-12-19 00:00:00
abstract::A new feather mite species, Tyrannidectes pteroptochi sp. n. (Astigmata: Proctophyllodidae: Pterodectinae), is described from the Moustached Turca Pteroptochos megapodius Kittlitz, 1830 (Passeriformes: Rhinocryptidae) in Chile. This is the first record of mites of the genus Tyrannidectes Mironov 2008 from this family ...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2015-0106
更新日期:2015-12-01 00:00:00
abstract::This paper characterizes the pattern of ectoparasite and endoparasite communities in an assemblage of 35 sympatric fish from different trophic levels in a tributary from the Amazon River system, northern Brazil. In detritivorous, carnivorous, omnivorous and piscivorous hosts, the species richness consisted of 82 ectop...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0035
更新日期:2018-06-26 00:00:00
abstract::Rhabdias stomatica sp. nov. from the lungs of Duttaphrynus stomaticus (Lutken, 1864) from Dehradun, Uttarakhand, India is described and illustrated. Rhabdias stomatica sp. nov. is the 16th species described from the Oriental biogeographical region and the 8th species from India. The new species is differentiated from ...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0020
更新日期:2018-03-26 00:00:00
abstract::A new species of parasitic mites, Myocoptes (Comyocoptes) nesokia sp. nov. (Acariformes: Myocoptidae) is described from Nesokia indica (Gray, 1830) (Rodentia: Muridae) from Pakistan. Females of this species differ from the morphologically similar species, Myocoptes (Comyocoptes) striatus Fain, 1970, by the presence of...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2017-0005
更新日期:2017-03-01 00:00:00
abstract::Felids are the only definitive hosts of Toxoplasma gondii. To lay a foundation for screening the T. gondii-felids interaction factors, we have developed a reproducible primary culture method for cat intestinal epithelial cells (IECs). The primary IECs were isolated from a new born cat's small intestine jejunum region ...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0041
更新日期:2018-06-26 00:00:00
abstract::A high infestation of the monogenean Gussevia tucunarense in a cultivation of bujurqui-tucunare was reported. The prevalence was 100%. The mean intensity and abundance of the parasite was 164.4 of parasites per individual. This is the first report of a high infestation by G. tucunarense in C. semifasciatus cultured fr...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-013-0129-7
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:There are currently nine monogenoidean species of Rhabdosynochus infecting the gill lamellae of wild and cultured centropomid fishes from tropical and subtropical waters of the western Atlantic and eastern Pacific Oceans. The purpose of the present study was to describe the morphological distinctiveness of two ...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1007/s11686-020-00303-1
更新日期:2020-11-08 00:00:00
abstract::The smokybrown cockroach Periplaneta fuliginosa has spread all over the world, and is now one of the most undesired invasive alien pests in Japan. Because cockroaches are generally infected by thelastomatid nematodes, they are being distributed around the world with their parasitic nematodes. Nothing is known about pa...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-014-0230-6
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Giardia duodenalis is a widespread protozoan parasite affecting humans and many species of animals, including dogs and cats. Due to its zoonotic potential, it is important to know the frequency of this parasite in companion animals. The aim of this study was to determine current epidemiological status of G. ...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1007/s11686-020-00292-1
更新日期:2020-10-11 00:00:00
abstract::With the development of anthelmintic resistance of parastic nematodes, it is necessary to isolate and study nematophagous fungi to screen out the native isolates for their potential in the biocontrol of domestic animal nematodosis. This study aimed to isolate the Arthrobotrys sinense (Monacrosporium sinense) of nemato...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0037
更新日期:2018-06-26 00:00:00
abstract:BACKGROUND:Parasitism is a complex problem that is often ignored in companion animals, including birds, unless it develops into a severe clinical disorder. The present study was, therefore, aimed to investigate the presence of the gastrointestinal nematode infecting the domestic pigeon and provide a complete morphologi...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00151-8
更新日期:2020-03-01 00:00:00
abstract::Malaria is wide spread in poor world and its burden has been assessed by the enumeration of malarial parasites in blood of patients. This study was designed to find a relationship between social structure, and spread of malaria in Khyber agency. The average parasite density was 2050 parasite/μl in Khyber Agency. Due t...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-013-0181-3
更新日期:2013-12-01 00:00:00
abstract::Cystic hydatidosis is a re-emerging parasitic zoonosis with worldwide distribution. The current study was carried out to investigate the possible role of rats in the epidemiology of such disease in urban and suburban areas. For this purpose, a total of 50 feral Norway rats (Rattus norvegicus) were collected from urban...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2016-0113
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:Trichinellosis is a severe zoonosis involving the activation of inflammatory cells, accompanied by the prominent expressions of proinflammatory cytokines in the host. Semen vaccariae, the seeds of Vaccaria segetalis (Neck.) Garcke. ex Asch. (Caryophyllaceae), is a famous traditional herb that is rich in va...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00064-6
更新日期:2019-09-01 00:00:00
abstract::This study describes the morphology of Procamallanus (Spirocamallanus) pintoi (Kohn et Fernandes, 1988), isolated from the intestine of Corydoras micracanthus Regan, 1912 and C. paleatus (Jenyns, 1842) (both Callichthyidae, Siluriformes) from Bermejo and Juramento River basins, respectively, province of Salta, Argenti...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2018-0068
更新日期:2018-09-25 00:00:00
abstract::The aim of this retrospective, population-based study was to characterize demographically and clinically cystic-echinococcosis (CE) in southern Israel, between 2005 and 2012. Newly-diagnosed (nd-CE) and past-diagnosed (pd-CE, diagnosed before the study) cases were defined. Two populations live in southern-Israel, rece...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2016-0024
更新日期:2016-01-01 00:00:00
abstract::Classification and identification of muscle-parasitizing didymozoids found in marine fish is difficult because of their novel parasitism and morphology. Recent sequence analysis has helped, but only seven sequences are available. Therefore, the usefulness of molecular methods for differentiation of muscle-parasitizing...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-014-0234-2
更新日期:2014-06-01 00:00:00
abstract::Parasitization of silkworm, Bombyx mori by invasive larva of dipteran parasitoid Exorista bombycis caused upto 20% revenue loss in sericulture. The parasitism was successful by suppressing host immune system however mechanism of immune suppression induced by E. bombycis is unknown which is unravelled here. The infesta...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1515/ap-2017-0086
更新日期:2017-12-20 00:00:00
abstract:PURPOSE:It is not clear that Blastocystis remains without damage to the digestive tract or has a pathogenic effect in relation to subtypes in immunocompromised people, such as cancer patients. The present study aimed to investigate the frequency and subtype distribution of Blastocystis in cancer patients who were follo...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.1007/s11686-020-00322-y
更新日期:2021-01-02 00:00:00
abstract:BACKGROUND:In spite of the global economic significance of sheep production, little is known about the prevalence of various Sarcocystis spp. infecting the domestic sheep (Ovis aries) in Egypt. MATERIALS AND METHODS:Muscle samples were collected from 175 sheep (> 2 years) slaughtered at El-Mahalla El-Kubra abattoir, G...
journal_title:Acta parasitologica
pub_type: 杂志文章
doi:10.2478/s11686-019-00070-8
更新日期:2019-09-01 00:00:00