Abstract:
BACKGROUND:Seizures as the unique initial manifestation of unruptured intracranial aneurysms have rarely been documented and not systematically described until now. OBJECTIVE:The purpose of this large retrospective analysis was to focus on the incidence of primary epileptogenic aneurysms and the influence of treatment on epilepsy. METHODS:Within a 16-year period, 347 unruptured aneurysms were surgically treated at centers in Munich (1992-2002) and Düsseldorf (2003-2008), Germany. Of this patient population, 9 patients presented exclusively with epileptic seizures or epileptic equivalents. In 3 of them, a high-lying internal carotid artery aneurysm was diagnosed that was buried in the parahippocampal gyrus. In 4 patients, a middle cerebral artery aneurysm also created contact with the mediotemporal lobe adjacent to the parahippocampal gyrus. An anterior communicating artery aneurysm and a pericallosal artery aneurysm were diagnosed in 2 additional patients. Two patients with a middle cerebral artery aneurysm were initially incompletely occluded with Guglielmi detachable coils and continued to have epilepsy after the intervention. In all but 1 patient, the aneurysms were clipped and completely removed. RESULTS:In all 8 patients operated on, there was no sign of hemorrhage intraoperatively but cortical gliosis was seen around the dome of the aneurysm. In all cases, the aneurysm and the surrounding gliosis, if existent, were surgically removed. Freedom from seizures without medication resulted for all patients after microsurgery. DISCUSSION:Seizures as a presenting symptom of unruptured intracranial aneurysms are rare. There seems to be a preponderance of aneurysms anatomically related to the temporomedial region. Elimination of the aneurysm and perifocal gliosis provides the possibility of a cure for the epilepsy.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Hänggi D,Winkler PA,Steiger HJdoi
10.1227/01.NEU.0000369515.95351.2Asubject
Has Abstractpub_date
2010-06-01 00:00:00pages
1161-5issue
6eissn
0148-396Xissn
1524-4040pii
00006123-201006000-00030journal_volume
66pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract:OBJECTIVE:A two-stage approach using orbitozygomatic (OZ) and retrosigmoid (RS) craniotomies is one option for the management of petroclival lesions with supratentorial extension. The goal of this study was to investigate the supratentorial and infratentorial exposures of the clivus obtained through this staged approac...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000326013.99562.eb
更新日期:2008-05-01 00:00:00
abstract::This study compares the acute and chronic response of brain tissue to injury by equal power density, focused argon (Ar) and carbon dioxide (CO2) laser beams. A cortical incision from 0.2-second laser pulses of 12.5 X 10(3) W/cm2 power density was made in the exposed cortex of 32 rats using either the CO2 or the Ar las...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198211000-00004
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:Relatively little attention has been paid to emotional outcome after subarachnoid hemorrhage (SAH). This study assessed levels of anxiety and depression among SAH survivors and related these to clinical indices. METHODS:Seventy SAH patients from a consecutive series of neurosurgical admissions participated i...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000097198.94828.e1
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:Meningiomas arising primarily within the internal auditory canal (IAC) are notably rare. By far the most common tumors that are encountered in this region are neuromas. We report a series of eight patients with meningiomas of the IAC, analyzing the clinical presentations, surgical management strategies, and c...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/01.neu.0000126887.55995.e7
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:For the prevention of postoperative CSF fistula a better understanding of origins and risk factors is necessary. OBJECTIVE:To identify the petrous bone air cell volume as a risk factor for developing CSF fistula, we performed a retrospective analysis. METHODS:From 2000 to 2007 519 patients had a retrosigmo...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e3181f88884
更新日期:2010-12-01 00:00:00
abstract::STRESS ULCERS OCCUR frequently in intensive care unit patients who have intracranial disease. After major physiological stress, endoscopic evidence of mucosal lesions of the gastrointestinal tract appears within 24 hours of injury; 17% of these erosions progress to clinically significant bleeding. Gastrointestinal hem...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-199708000-00017
更新日期:1997-08-01 00:00:00
abstract::The syndrome of inappropriate antidiuretic hormone secretion (SIADH) developed approximately 7 days after a spontaneous subarachnoid hemorrhage in a 63-year-old woman with an anterior cerebral artery aneurysm. The hyponatremia associated with this syndrome resulted in a deterioration of the patient's clinical conditio...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-197811000-00016
更新日期:1978-11-01 00:00:00
abstract:OBJECTIVE:To conduct a pilot trial of mild intraoperative hypothermia during cerebral aneurysm surgery. METHODS:One hundred fourteen patients undergoing cerebral aneurysm clipping with (n = 52) (World Federation of Neurological Surgeons score < or =III) and without (n = 62) acute aneurysmal subarachnoid hemorrhage (SA...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006123-199901000-00009
更新日期:1999-01-01 00:00:00
abstract::We have used three-dimensional reconstruction magnetic resonance imaging techniques to understand the anatomic complexity of operative brain lesions and to improve preoperative surgical planning. We report our experience with 14 cases, including intra- and extra-axial tumors and a vascular malformation. In each case, ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:The high rate of mutagenesis in malignant cells has been considered to be a primary factor in the appearance of chemotherapy-resistant cell clones in glioblastomas. Quinacrine binds strongly to deoxyribonucleic acid, preventing mutagenesis. We investigated whether quinacrine could improve carmustine therapy i...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200110000-00033
更新日期:2001-10-01 00:00:00
abstract::The spinal form of brucellosis is still a disabling disease in many countries outside North America and northern and central Europe. Fifteen consecutive cases of spinal brucellosis diagnosed and treated over a 20-year period were reviewed retrospectively. Six patients were farmers, while 10 patients had a history of i...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199311000-00008
更新日期:1993-11-01 00:00:00
abstract::CSF dynamics were determined as a function of intracranial pressure in patients with pseudotumor cerebri. Servocontrolled variable rate lumbar infusions were used to determine net CSF-absorptive capacities and resting pressures in 10 patients; serial studies were done in 5 of the patients. Nearly all of the patients h...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-197908000-00003
更新日期:1979-08-01 00:00:00
abstract:OBJECTIVE:To assess whether the development of delayed ischemic deficits (DIDs) after aneurysmal subarachnoid hemorrhage can be predicted using transcranial Doppler ultrasonography and the transient hyperemic response test (THRT). METHODS:An increase in the middle cerebral artery peak flow velocity (FV) of more than 9...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200010000-00004
更新日期:2000-10-01 00:00:00
abstract::The source of bleeding remains obscure in most cases of subarachnoid hemorrhage (SAH) with a negative angiogram. From January 1, 1989, to July 1, 1993, 40 patients were admitted to the Massachusetts General Hospital with angiogram-negative SAH; 9 of these patients underwent surgical exploration. In seven of these expl...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199507000-00007
更新日期:1995-07-01 00:00:00
abstract::Magnetic resonance neurography was used to directly image cervical spinal nerves in patients with clinical and radiographic evidence of cervical radiculopathy. A magnetic resonance imaging phased-array coil system was used to obtain high-resolution coronal T1-weighted spin echo, coronal/axial T2-weighted fast spin ech...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199603000-00013
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:Hypomania accounts for approximately 4% to 13% of psychotropic adverse events during subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease. Diffusion of current into the inferior and medial "limbic" STN is often reported to be the cause. We suggest a different explanation, in which th...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1227/01.NEU.0000345631.54446.06
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:We report 81 patients with a traumatic intracerebellar hemorrhagic contusion or hematoma managed between 1996 and 1998 at 13 Italian neurosurgical centers. METHODS:Each center provided data about patients' clinicoradiological findings, management, and outcomes, which were retrospectively reviewed. RESULTS:A...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1097/00006123-200201000-00004
更新日期:2002-01-01 00:00:00
abstract::Between June 1979 and May 1994, I performed 148 unilateral or bilateral sympathectomies on 247 limbs in 110 patients using a percutaneous radiofrequency technique, usually on an outpatient surgery basis. Patient ages ranged from 10 to 81 years, with 45 male and 65 female patients. Four patients had unsuccessfully unde...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::For several decades, the clinical study of Parkinson's disease has driven an increasingly sophisticated understanding of the dopaminergic system and its complex role in modulating motor behavior. This article reviews salient areas of research in this field, commencing with the molecular biology of the development of t...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/01.NEU.0000249209.11967.CB
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Giant fusiform and dolichoectatic aneurysms of the basilar trunk and vertebrobasilar junction (BTVBJ-GFDA) are extremely difficult to treat. OBJECTIVE:To evaluate factors influencing survival and outcome of BTVBJ-GFDA by performing a retrospective multicenter cohort study. METHODS:A total of 32 patients wi...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa317
更新日期:2020-12-15 00:00:00
abstract:BACKGROUND:Elderly patients with glioblastoma have an especially poor prognosis; optimizing their medical and surgical care remains of paramount importance. OBJECTIVE:To investigate patient and treatment characteristics of elderly vs nonelderly patients and develop an algorithm to predict elderly patients' survival. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyx148
更新日期:2018-01-01 00:00:00
abstract::Premature closure of the metopic suture results in a deformity ranging from a minor variation to a severe cosmetic deformity. The three principal abnormalities comprising metopic synostosis are trigonocephaly secondary to the restriction of growth of both frontal bones, deficient lateral supraorbital rims, and hypotel...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198608000-00008
更新日期:1986-08-01 00:00:00
abstract:OBJECTIVE:Carotid endarterectomy with a patch graft (Patch CEA) has been our standard treatment for patients with carotid artery stenosis, but carotid artery stenting (CAS) has emerged as an alternative. The purpose of this study was to compare the postoperative changes in the configurations and the flow velocities of ...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1227/01.NEU.0000358952.12917.DF
更新日期:2009-11-01 00:00:00
abstract::Intracranial electrical recordings and stimulation of neurosurgical patients have been central to the advancement of human neuroscience. The use of these methods has rapidly expanded over the last decade due to theoretical and technical advances, as well as the growing number of neurosurgical patients undergoing funct...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1093/neuros/nyx361
更新日期:2018-07-01 00:00:00
abstract::A case is reported of an arteriovenous malformation in the left motor speech area which was successfully excised without aphasia in a right-handed man. Preoperative sodium amobarbital carotid infusion testing demonstrated that the patient had right hemisphere dominance for speech. A review of the literature suggests t...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-197709000-00004
更新日期:1977-09-01 00:00:00
abstract::Anterior cervical instrumentation is used as an adjunct to bone fusion; however, definitive biomechanical data to support some applications and techniques are lacking. In the absence of supportive experimental data, posterior cortical penetration has been recommended with the Caspar system. Previously, we compared the...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199312000-00013
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Spontaneous herniation of the spinal cord substance through a previously uninjured and/or untouched dura is a very exceptional occurrence. Spontaneous spinal cord herniation, which was first reported 25 years ago, is a cause of myelopathy that is treatable but difficult to diagnose. CLINICAL P...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-200002000-00044
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Surgery for degenerative cervical spine disease has escalated since the 1990s. Fusion has become the mainstay of surgery despite concerns regarding adjacent segment degeneration. The patient-specific trends in reoperations have not been studied previously. OBJECTIVE:To analyze the occurrence, risk factors, ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa464
更新日期:2020-12-28 00:00:00
abstract::Historical observations and interpretations regarding the treatment of components of the nervous system can be found in the writings of the Bible and Talmud. A review of topics germane to modern neuroanatomy, neurology, and neurosurgery from these early, rich writings is presented herein. These historic writings provi...
journal_title:Neurosurgery
pub_type: 历史文章,杂志文章
doi:10.1227/01.NEU.0000335082.54975.89
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Treatment of one side in cases of dissecting aneurysms of the bilateral vertebral arteries (VAs) with subarachnoid hemorrhage may result in dissection or rupture on the contralateral side. CLINICAL PRESENTATION:Three patients presented with dissecting aneurysms of the bilateral VAs with subara...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200206000-00033
更新日期:2002-06-01 00:00:00