Abstract:
:CSF dynamics were determined as a function of intracranial pressure in patients with pseudotumor cerebri. Servocontrolled variable rate lumbar infusions were used to determine net CSF-absorptive capacities and resting pressures in 10 patients; serial studies were done in 5 of the patients. Nearly all of the patients had abnormally low CSF-absorptive capacities. On the other hand, marked elevations in resting pressure were not a constant feature of the disease. Concurrent changes in the cerebrovascular bed could introduce errors into this manometric determination of CSF dynamics; the significance of this potential artifact is examined. The results of this study suggest that the CSF compartment may be of etiological importance in the pathophysiology of pseudotumor cerebri.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Sklar FH,Beyer CW Jr,Ramanathan M,Cooper PR,Clark WKdoi
10.1227/00006123-197908000-00003subject
Has Abstractpub_date
1979-08-01 00:00:00pages
208-16issue
2eissn
0148-396Xissn
1524-4040journal_volume
5pub_type
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