The dopaminergic nigrostriatal system and Parkinson's disease: molecular events in development, disease, and cell death, and new therapeutic strategies.

abstract：BACKGROUND:Minimal clinically important difference (MCID) is determined when a patient or physician defines the minimal change that outweighs the costs and untoward effects of a treatment. These measurements are "anchored" to validated quality-of-life instruments or physician-rated, disease-activity indices. To capture...

journal_title：Neurosurgery

authors： Zervos TM,Asmaro K,Air EL

更新日期：2020-12-28 00:00:00

abstract：:Three cases of extracerebral cavernous angiomas of the cavernous sinus in the middle fossa are reported. These are rare lesions that primarily affect women and are usually associated with acute or subacute onset of visual symptoms: diplopia, exophthalmos, and decreased visual acuity. The growth of the lesion often ero...

journal_title：Neurosurgery

authors： Rigamonti D,Pappas CT,Spetzler RF,Johnson PC

更新日期：1990-08-01 00:00:00

abstract：:During a 34-month period, 12 cases of delayed traumatic intracerebral hematoma (DTICH) were diagnosed among 162 consecutive prospectively studied patients admitted to the Medical College of Virginia with severe closed head injuries. All patients were unresponsive to command and unable to utter formed words at the time...

journal_title：Neurosurgery

authors： Gudeman SK,Kishore PR,Miller JD,Girevendulis AK,Lipper MH,Becker DP

更新日期：1979-09-01 00:00:00

abstract：:When confronted with a patient with a brachial plexus injury, how often as neurosurgeons do we consult an atlas to confirm the anatomy of the brachial plexus and then attempt to establish the location of the lesion? Similar difficulties are encountered with lumbar and sacral plexus lesions. In a project organized to a...

journal_title：Neurosurgery

authors： Fisher WS 3rd

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:The bony and vascular anatomic features in the region of the petrous apex can vary significantly. These variations affect the operative view obtained via extended subtemporal or anterior transpetrosal approaches to cranial base lesions for individual patients. The goal of this study was to evaluate three-dime...

journal_title：Neurosurgery

authors： Villavicencio AT,Leveque JC,Bulsara KR,Friedman AH,Gray L

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Intracranial solitary fibrous tumors have been described previously, but intraventricular solitary fibrous tumors are extremely rare. We present what is, to our knowledge, the first reported case of solitary fibrous tumor in the third ventricle. CLINICAL PRESENTATION:A 63-year-old man presente...

journal_title：Neurosurgery

authors： Koçak A,Cayli SR,Saraç K,Aydin NE

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Deep brain stimulation (DBS) has become routine for the treatment of Parkinson's disease and essential tremor. Because both of these disorders are common in patients older than the age of 60, neurosurgeons are likely to encounter increasing numbers of patients who require DBS surgery but who already have anot...

journal_title：Neurosurgery

authors： De Los Reyes K,Chandrasekhar SS,Tagliati M,Alterman R

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To test the spatial accuracy of coordinates generated from magnetic resonance imaging (MRI) scans, using the Brown-Roberts-Wells head frame and localizer system (Radionics, Inc., Burlington, MA). METHODS:An anthropomorphic head phantom, consisting of a two-dimensional lattice of acrylic spheres (4-mm diamete...

journal_title：Neurosurgery

authors： Orth RC,Sinha P,Madsen EL,Frank G,Korosec FR,Mackie TR,Mehta MP

更新日期：1999-12-01 00:00:00

abstract：:A case of symptomatic Rathke's cleft cyst is described. In spite of the intrasellar component and radiological and clinical evidence of involvement of the pituitary gland, the sella turcica was minimally involved. MRI afforded optimal visualization and localization of the intra- and suprasellar components vis-à-vis th...

journal_title：Neurosurgery

authors： Wagle VG,Nelson D,Rossi A,Uphoff D

更新日期：1989-02-01 00:00:00

abstract：:A major limitation to the effective treatment of intrinsic mass lesions of the brain stem has been the inability to clearly define the pathological anatomy radiographically. The improved soft tissue resolution offered by magnetic resonance imaging, as compared with axial computed tomography, now makes it possible not ...

journal_title：Neurosurgery

authors： Heffez DS,Zinreich SJ,Long DM

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:Ollier disease (OD) and Maffucci syndrome are closely related, very rare syndromes, that are both associated with multiple sites of chondrodysplasia. They differ primarily with the additional association of Maffucci syndrome with vascular abnormalities, including hemangiomas. Both are associated with chondros...

journal_title：Neurosurgery

authors： Ranger A,Szymczak A

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Lymphocytic hypophysitis is being recognized with increasing frequency, but the long-term course is not well known. Recurrence of lymphocytic hypophysitis after a long interval has never been reported. CLINICAL PRESENTATION:A 53-year-old woman presented with central diabetes insipidus. Magneti...

journal_title：Neurosurgery

authors： Nishioka H,Ito H,Fukushima C

更新日期：1997-09-01 00:00:00

abstract：:The authors present a review of published experience with intracranial-extracranial arterial bypass grafting. The procedure is technically feasible and has a relatively low morbidity and mortality when performed by experienced microvascular surgeons. However, its therapeutic value is still unproven. ...

journal_title：Neurosurgery

authors： Samson DS,Boone S

更新日期：1978-07-01 00:00:00

abstract：:Fifty-one surgical decompressions without nerve transposition for ulnar neuropathy were performed in 46 patients. All of the patients were men with an average age of 59 years at the time of surgery. The follow-up range was between 5 and 32 months (average, 17.8 months). The disease involved the nondominant arm in 24 p...

journal_title：Neurosurgery

authors： LeRoux PD,Ensign TD,Burchiel KJ

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:Acquired immunity has been demonstrated in Fischer rats bearing syngeneic 9L tumors after herpes simplex virus (HSV) thymidine kinase (TK) gene transfection and ganciclovir treatment. The nature of this immunity in rats and its relevance to the HSV TK/ganciclovir protocol for human subjects remain to be deter...

journal_title：Neurosurgery

authors： Parsa AT,Chi JH,Hurley PT,Jeyapalan SA,Bruce JN

更新日期：2001-09-01 00:00:00

abstract：:A 1-month-old infant with a Dandy-Walker malformation underwent the placement of a ventriculoperitoneal shunt to treat progressive hydrocephalus. On the initial computed tomographic scan, a subependymal cystic lesion larger than 1 cm in diameter was noted in the head of the right caudate nucleus, which enlarged to 3 c...

journal_title：Neurosurgery

authors： Rabb CH,Levy ML,McComb JG,Feigenbaum JA

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:Vascular remodeling via apoptotic mechanisms is an important factor in vascular diseases. c-Jun amino-terminal kinase (JNK) is a member of the mitogen-activated protein kinase family and initiates apoptosis mainly via phosphorylation of the c-Jun transcription factor. We performed this study to clarify the ro...

journal_title：Neurosurgery

authors： Takagi Y,Ishikawa M,Nozaki K,Yoshimura S,Hashimoto N

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Five cases of cerebellar hemorrhagic infarction complicating pterional craniotomy are presented. Recognition of this rare complication may be delayed, with catastrophic consequences, because clinicians are unaware of the possibility. We suggest that the mechanism of this complication is disloca...

journal_title：Neurosurgery

authors： Papanastassiou V,Kerr R,Adams C

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Currently, because of the precision of stereotactic radiosurgery, radiation can now be delivered by techniques that shape the radiation beam to the tissue target for a variety of clinical applications. This avoids unnecessary and potentially damaging irradiation of surrounding tissues inherent in conventional...

journal_title：Neurosurgery

authors： Zeman RJ,Wen X,Ouyang N,Rocchio R,Shih L,Alfieri A,Moorthy C,Etlinger JD

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To evaluate patients' clinical outcome, survival, and performance status, at the long-term follow-up evaluation after aggressive microsurgical resection of petroclival meningiomas. METHODS:During a 13-year period (1991-2004), 150 patients underwent 207 operative procedures for resection of petroclival mening...

journal_title：Neurosurgery

authors： Natarajan SK,Sekhar LN,Schessel D,Morita A

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Stereotactic radiosurgery is a commonly used treatment method in the management of metastatic brain tumors. When lesions enlarge after radiosurgery, it may represent tumor regrowth, radiation necrosis, or both. The purpose of this study was to determine whether standard magnetic resonance imaging (MRI) sequen...

journal_title：Neurosurgery

authors： Dequesada IM,Quisling RG,Yachnis A,Friedman WA

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Free radicals and lipid peroxidation are thought to be related to the vasospasm generation after subarachnoid hemorrhage (SAH). Plasma platelet-activating factor-acetyl hydrolase (PAF-AH) degrades phospholipids with an oxidatively modified fatty acyl chain. OBJECTIVE:To compare plasma PAF-AH activity and fr...

journal_title：Neurosurgery

authors： Hirashima Y,Doshi M,Hayashi N,Endo S,Akazawa Y,Shichiri M,Yoshida Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Lumbar discectomy is the most commonly performed spine procedure. Academic spine centers with potentially differing caseloads and experience may have different outcomes. OBJECTIVE:To determine whether the choice of center in which surgery is performed affects lumbar discectomy outcomes. METHODS:Spine Patie...

journal_title：Neurosurgery

authors： Desai A,Bekelis K,Ball PA,Lurie J,Mirza SK,Tosteson TD,Zhao W,Weinstein JN

更新日期：2012-10-01 00:00:00

abstract：:Although thrombocytopenia occurs in approximately 10% of medical patients who receive heparin, this complication has not been described in neurosurgical patients. We report the clinical course of two patients who in the immediate postoperative period developed heparin-associated thrombocytopenia that resulted in signi...

journal_title：Neurosurgery

authors： Doty JR,Alving BM,McDonnell DE,Ondra SL

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Multimodal intracranial monitoring in the neurosurgical patient requires insertion of probes through multiple craniostomies. OBJECTIVE:To report our 5-year experience with a novel device allowing multimodal monitoring though a single twist-drill hole. METHODS:All devices (Hummingbird Synergy, Innerspace) w...

journal_title：Neurosurgery

authors： Chohan MO,Akbik OS,Ramos-Canseco J,Ramirez PM,Murray-Krezan C,Berlin T,Olin K,Taylor CL,Yonas H

更新日期：2014-09-01 00:00:00

abstract：:A case of ulnar neuropathy at the elbow produced by spontaneous intraneural hemorrhage in a patient with acquired immunodeficiency syndrome and thrombocytopenia is reported. Intraneural hemorrhage in patients with bleeding disorders occurs infrequently. It consists of acute intrafascicular bleeding, presumably produci...

journal_title：Neurosurgery

authors： Poppi M,Staffa G,Martinelli P,Fabrizi AP,Giuliani G

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:Facial nerve paresis and hearing loss are common complications after vestibular schwannoma surgery. Experimental and clinical studies point to a beneficial effect of nimodipine and hydroxyethyl starch for preservation of cochlear nerve function. A retrospective analysis was undertaken to evaluate the effect o...

journal_title：Neurosurgery

authors： Strauss C,Romstöck J,Fahlbusch R,Rampp S,Scheller C

更新日期：2006-09-01 00:00:00

abstract：:The paraclinoid area is investigated anatomically for possible microneurosurgical approaches to the C3 segment of the internal carotid artery and to structures in the vicinity of the anterior siphon knee. Removal of the anterior clinoid process reveals a tight connective tissue ring that fixes the internal carotid art...

journal_title：Neurosurgery

authors： Knosp E,Müller G,Perneczky A

更新日期：1988-05-01 00:00:00

abstract：:Endovascular treatment for acute ischemic stroke has changed remarkably over the past decade. Beginning with IA thrombolytic administration, endovascular strategies have evolved to include aspiration, self-expanding intracranial stents, and now retrievable stents. With the recent publication of 5 randomized, controlle...

journal_title：Neurosurgery

authors： Munich SA,Mokin M,Snyder KV,Siddiqui AH,Hopkins LN,Levy EI

更新日期：2015-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the influence of previous treatment on outcome and sensory disturbance after a retrogasserian glycerol injection for trigeminal neuralgia. Ninety-nine patients with trigeminal neuralgia underwent a retrogasserian glycerol rhizotomy. Fifty-three of those patients experienced...

journal_title：Neurosurgery

authors： Bergenheim AT,Hariz MI

更新日期：1995-02-01 00:00:00