Abstract:
BACKGROUND:Minimal clinically important difference (MCID) is determined when a patient or physician defines the minimal change that outweighs the costs and untoward effects of a treatment. These measurements are "anchored" to validated quality-of-life instruments or physician-rated, disease-activity indices. To capture the subjective clinical experience in a measurable way, there is an increasing use of MCID. OBJECTIVE:To review the overall concept, method of calculation, strengths, and weaknesses of MCID and its application in the neurosurgical literature. METHODS:Recent articles were reviewed based on PubMed query. To illustrate the strengths and limitations of MCID, studies regarding the measurement of pain are emphasized and their impact on subsequent publications queried. RESULTS:MCID varies by population baseline characteristics and calculation method. In the context of pain, MCID varied based on the quality of pain, chronicity, and treatment options. CONCLUSION:MCID evaluates outcomes relative to whether they provide a meaningful change to patients, incorporating the risks and benefits of a treatment. Using MCID in the process of evaluating outcomes helps to avoid the error of interpreting a small but statistically significant outcome difference as being clinically important.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Zervos TM,Asmaro K,Air ELdoi
10.1093/neuros/nyaa490subject
Has Abstractpub_date
2020-12-28 00:00:00eissn
0148-396Xissn
1524-4040pii
6053822pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract:OBJECTIVE AND IMPORTANCE:Intracranial germinomas often disseminate via the ventricular and subarachnoid pathways, but seeding to the perioptic arachnoid space is extremely unusual. We report two cases of recurrent germinoma seeding in the optic nerve. CLINICAL PRESENTATION:Two men with pure germinoma were initially tr...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-200101000-00041
更新日期:2001-01-01 00:00:00
abstract::Currently, only presumptive diagnosis of chronic traumatic encephalopathy (CTE) can be made in living patients. We present a modality that may be instrumental to the definitive diagnosis of CTE in living patients based on brain autopsy confirmation of [F-18]FDDNP-PET findings in an American football player with CTE. [...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyx536
更新日期:2018-02-01 00:00:00
abstract::The sciatic nerve is by far the most common nerve accidentally injured during intramuscular injection. Despite its close proximity to the sciatic nerve, however, injury to the posterior femoral cutaneous nerve is apparently quite rare. In this report, clinical features of a patient with isolated injection injury to th...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-198911000-00027
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:The presence of intracerebral hematoma from aneurysm rupture is an indication for craniotomy for clot evacuation and aneurysm clipping. Some centers have begun securing aneurysms with coil embolization followed by clot evacuation in the operating room. This approach requires transporting a patient from the a...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000000650
更新日期:2015-03-01 00:00:00
abstract::The spinal form of brucellosis is still a disabling disease in many countries outside North America and northern and central Europe. Fifteen consecutive cases of spinal brucellosis diagnosed and treated over a 20-year period were reviewed retrospectively. Six patients were farmers, while 10 patients had a history of i...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199311000-00008
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Five cases of cerebellar hemorrhagic infarction complicating pterional craniotomy are presented. Recognition of this rare complication may be delayed, with catastrophic consequences, because clinicians are unaware of the possibility. We suggest that the mechanism of this complication is disloca...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-199610000-00040
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the benefits of intraoperative autotransfusion of autologous blood on the conservation of allogenic blood, including cost-effectiveness and the consequences for hemoglobin level and coagulation tests. METHODS:The Hoemonetics Cell Saver 4 autotransfusion system (Hoemo...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199704000-00021
更新日期:1997-04-01 00:00:00
abstract::Localization of the placental form of glutathione S-transferase (GST-pi) messenger ribonucleic acid (mRNA) in three human glioma cell lines (A172, T98G, and Tc77) was studied by in situ hybridization with digoxigenin-labeled GST-pi complementary DNA followed by immunocytochemistry with antidigoxigenin antibody. A172 g...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199307000-00016
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:Spinal cord dose limits are critically important for the safe practice of spine stereotactic body radiotherapy (SBRT). However, the effect of inherent spinal cord motion on cord dose in SBRT is unknown. OBJECTIVE:To assess the effects of cord motion on spinal cord dose in SBRT. METHODS:Dynamic balanced fas...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa202
更新日期:2020-06-04 00:00:00
abstract:BACKGROUND:No conventional surgical intervention has been shown to improve outcomes for patients with spontaneous intracerebral hemorrhage (ICH) compared with medical management. OBJECTIVE:We report the initial multicenter experience with a novel technique for the minimally invasive evacuation of ICH using the Penumbr...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1227/NEU.0000000000000698
更新日期:2015-06-01 00:00:00
abstract::This study evaluated quality of life in 78 patients with closed head injury (CHI) 2 to 4 years postinjury. Using both interview data and mean data from the Sickness Impact Profile questionnaire, impaired quality of life was observed in the areas of psychosocial functioning, social role functioning, leisure activities,...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198611000-00004
更新日期:1986-11-01 00:00:00
abstract::This investigation tested the hypothesis that the degree of impairment to memory function caused by an anterior temporal lobectomy (ATL) is inversely related to the pathological status of the resected hippocampus. Specifically, the greatest risk to postoperative memory function should be to patients with no or minimal...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199210000-00006
更新日期:1992-10-01 00:00:00
abstract::Holographic technology has recently been modified in such a manner that it may now provide clinical use. It allows the visualization of complex structures in three dimensions and permits clinician interaction with the image, which, in turn, provides significant additional geometric and anatomic information. To objecti...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199510000-00015
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Randomized controlled trials evaluating mechanical thrombectomy (MT) for acute ischemic stroke predominantly studied anterior circulation patients. Both procedural and clinical predictors of outcome in posterior circulation patients have not been evaluated in large cohort studies. OBJECTIVE:To investigate t...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa179
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:Long-term remission rates from endoscopic transsphenoidal surgery for acromegaly and their relationship to prognostic indicators of disease aggressiveness are not well documented. OBJECTIVE:To investigate long-term remission rates in patients with acromegaly after endoscopic transsphenoidal surgery, and cor...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyx020
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND IMPORTANCE:Comminuted sacral fractures present significant challenges for operative management. Open and percutaneous sacroiliac screws have been used for stabilization but carry not insignificant rates of complications, including wound infection for the former and malposition and neurological injury for...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31826cdfd7
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND AND IMPORTANCE:The safety of flow-diverting stents for the treatment of ruptured intracranial aneurysms is unknown. CLINICAL PRESENTATION:A 35-year-old woman with a ruptured dissecting aneurysm of the intradural right vertebral artery and incorporating the right posterior inferior cerebellar artery was trea...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31827fc9be
更新日期:2013-06-01 00:00:00
abstract::Fetal visualization in utero can be routinely accomplished using noninvasive ultrasound techniques that do not administer ionizing radiation. Image resolution with real time sonography is sufficient to demonstrate details of possible congenital central nervous system malformations before delivery. The case reported il...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198306000-00016
更新日期:1983-06-01 00:00:00
abstract:OBJECTIVE:Although the necessity of craniotomy for an unruptured cerebral aneurysm (UCA) is controversial, surgery is warranted if surgical risks are less than the risks of natural history. In this study, we investigated the need for craniotomy for UCAs on the basis of surgical risk. METHODS:History of cerebrovascular...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000148897.28828.85
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Intraoperative measurements of cerebral blood flow are of interest during vascular neurosurgery. Near-infrared indocyanine green (ICG) fluorescence angiography was introduced for visualizing vessel patency intraoperatively. However, quantitative information has not been available. OBJECTIVE:To report our ex...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31822f7d7c
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:This study was conducted to investigate the efficacy of treating central or paramedian disc herniations of the upper lumbar levels, including the thoracolumbar junction, through the oblique paraspinal approach. We published a technical case report on this subject in 2004. METHODS:Nineteen consecutive patient...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000348299.89232.C2
更新日期:2009-07-01 00:00:00
abstract::A case of hemangioma calcificans in the 4th ventricle is reported. Skull x-ray films demonstrated a dense calcification in the posterior fossa. Computed tomography disclosed a hyperdense mass in the 4th ventricle. The clinical picture was of increased intracranial pressure due to obstructive hydrocephalus. An hemangio...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198406000-00016
更新日期:1984-06-01 00:00:00
abstract::A consecutive series of 100 individuals with aneurysmal subarachnoid hemorrhage were subjected to early aneurysm operation followed by subsequent intravenous administration of the calcium antagonist nimodipine during the critical period for symptomatic vasospasm. A total of 85 patients were in Hunt and Hess neurologic...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198602000-00005
更新日期:1986-02-01 00:00:00
abstract::The problem of gastric secretory and mucosal injury response was evaluated in 19 patients who had suffered a severe head injury. Fifteen of 19 patients had some evidence of gastrointestinal hemorrhage. In 7 cases, this was marked. The mean volume of gastric secretions ranged from 36.4 ml/hour on Day 1 to 47.6 ml/hour ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198302000-00007
更新日期:1983-02-01 00:00:00
abstract::Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when boron-10, a stable isotope, is irradiated with low-energy thermal neutrons to yield alpha particles and recoiling lithium-7 nuclei. For BNCT to be successful, a large number of 10B atoms must be localized on or preferably within neo...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-199903000-00001
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:Vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) is a potent angiogenic growth factor implicated in the tumor angiogenesis/metastasis of a number of human cancers. Activation of receptors for VEGF/VPF is specifically mitogenic to endothelial cells and increases their permeability. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199705000-00027
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:We report the long-term follow-up of 31 patients with cavernous sinus meningiomas who were treated either with surgery and radiotherapy (RT) or with RT alone. This retrospective review was undertaken to compare long-term efficacy and morbidity of RT with or without previous surgery versus complete, aggressive...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200102000-00006
更新日期:2001-02-01 00:00:00
abstract::Neurosurgery at the University of Michigan was established as a specialty three-quarters of a century ago by Max Minor Peet. It developed under the successive leadership of Edgar Allan Kahn, Richard Coy Schneider, and Julian T. Hoff. Each has made unique contributions to the program, which has a strong tradition of te...
journal_title:Neurosurgery
pub_type: 传,历史文章,杂志文章
doi:10.1227/00006123-199507000-00017
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Nonfunctioning pituitary adenomas (NFPAs) are the most frequent pituitary tumors. Visual symptoms from NFPAs are common and include visual field defects, loss of central vision, and motility problems resulting in diplopia. OBJECTIVE:To create evidence-based guidelines in an attempt to formulate guidance for...
journal_title:Neurosurgery
pub_type: 杂志文章,实务指引,评审
doi:10.1227/NEU.0000000000001388
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:A patient with an anterior communicating artery aneurysm was treated by use of endovascular coiling, and a Guglielmi detachable coil (Boston Scientific/Target, Fremont, CA) fractured distal to its connection to the delivering catheter. The unraveled coil floated out from the aneurysm to extend into the bifurc...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200204000-00048
更新日期:2002-04-01 00:00:00