Abstract:
:This study aimed to investigate the association between the volume-dependent parameters in 18F-fluorodeoxyglucose-positron emission tomography (18F-FDG PET/CT) and a recurrence of thymic carcinoma. A retrospective chart review was performed based on our multi-institutional database to identify patients undergoing PET prior to resection of thymic carcinoma or neuroendocrine carcinoma between 1991 and 2018. The PET parameters (metabolic tumor volume and total lesion glycolysis) were evaluated retrospectively. The relevant factors were extracted and a survival analysis was performed using the Kaplan-Meier method. Sixteen patients were thus deemed to be eligible for analysis. The median follow-up period following resection was 2.65 years (range: 0.96-0.68 years). The recurrence-free survival was significantly longer in patients with a metabolic tumor volume < = 22.755 cm3 and with total lesion glycolysis < = 105.4006 g/mL (p = 0.001 and 0.001, respectively, by a log-rank test). The metabolic tumor volume and total lesion glycolysis may, therefore, be predictive of the postoperative recurrence of thymic carcinoma.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Hamaji M,Koyasu S,Omasa M,Nakakura A,Morita S,Nakagawa T,Miyahara S,Miyata R,Yokoyama Y,Kawakami K,Suga M,Takahashi M,Terada Y,Muranishi Y,Miyahara R,Sumitomo R,Huang CL,Aoyama A,Takahashi Y,Date Hdoi
10.1007/s00595-020-02045-zsubject
Has Abstractpub_date
2021-02-01 00:00:00pages
322-326issue
2eissn
0941-1291issn
1436-2813pii
10.1007/s00595-020-02045-zjournal_volume
51pub_type
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