Abstract：
:Excessive surgical stress and postoperative complications cause a storm of perioperative cytokine release, which has been shown to enhance tumor metastasis in experimental models. We have named this phenomenon "surgical oncotaxis". The mechanisms that underpin this process are thought to be excessive corticosteroid secretion, coagulopathy in the peripheral vasculature, immune suppression and excessive production of reactive oxygen species. Nuclear factor-kappa B (NFkB) activation plays a key role in these mechanisms. Minimally invasive surgical techniques should be used, and postoperative complications should be avoided whenever possible to lessen the impact of surgical oncotaxis. Furthermore, there may be a role for a small preoperative dose of corticosteroid or the use of free radical scavengers in the perioperative period. Recently, there has been a great deal of interest in omega-3 fatty acid, because it regulates NFkB activation. The use of multimodal treatments that regulate surgical oncotaxis may be as important as chemotherapy for determining the outcome of patients with cancer undergoing surgery.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Hirai T,Matsumoto H,Kubota H,Yamaguchi Ydoi
10.1007/s00595-013-0627-0subject
Has Abstractpub_date
2014-05-01 00:00:00pages
804-11issue
5eissn
0941-1291issn
1436-2813journal_volume
44pub_type
杂志文章,评审相关文献
SURGERY TODAY文献大全abstract：:The results of surgical treatment for advanced esophageal cancer remain extremely poor. Irradiation and chemotherapy are not superior to surgery. Perioperative morbidity and the influence on long-term survival of a combination of surgery and preoperative chemotherapy were investigated in patients with advanced esophag...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF02482310
更新日期：1999-01-01 00:00:00
abstract：:We report herein the rare case of a 15-year-old girl with chronic appendicitis in whom the appendix was clearly depicted by a barium enema (BE) examination. The patient presented with a 4-month history of diffuse abdominal pain and tenderness in the lower abdomen. Neither computed tomography nor ultrasonography showed...
journal_title：Surgery today
pub_type： 杂志文章,评审
doi：10.1007/BF02385810
更新日期：1997-01-01 00:00:00
abstract：:Double common bile duct (DCBD) is a rare congenital anomaly of the biliary system, often associated with biliary lithiasis, choledochal cyst, pancreaticobiliary maljunction (PBM), and upper gastrointestinal tract malignancies. We report a case of type I DCBD with choledochal cyst and cholelithiasis in a 52-year-old Ch...
journal_title：Surgery today
pub_type： 杂志文章,评审
doi：10.1007/s00595-013-0561-1
更新日期：2014-04-01 00:00:00
abstract：:Mesenchymal hamartoma of the liver (MHL) is an uncommon benign tumor found primarily in children younger than 2 years of age. We report a rare case of MHL with a daughter nodule and atypical histological findings in a 14-month-old girl. On admission, computed tomography, magnetic resonance imaging, and angiography sho...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-007-3494-8
更新日期：2007-01-01 00:00:00
abstract：:This report describes a case of carcinosarcoma of the duodenum. Carcinosarcoma of the duodenum is a very rare tumor. A 72-year-old man was referred to the hospital because of appetite loss. Endoscopy demonstrated an irregularly depressed lesion (type 3) in the descending portion of the duodenum opposite to the ampulla...
journal_title：Surgery today
pub_type： 杂志文章,评审
doi：10.1007/s00595-009-3955-3
更新日期：2009-01-01 00:00:00
abstract：:The purpose of this retrospective study was to examine the influence of cigarette smoking on the recurrence of Crohn's disease after resection. Between 1975 and 1990, 141 patients underwent primary ileocolonic resection for ileocecal Crohn's disease, 79 of whom were nonsmokers and 62 of whom were smokers at the time o...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF02482360
更新日期：1999-01-01 00:00:00
abstract：:We report herein the case of a patient who developed a malignant recurrence of pheochromocytoma 13 years after undergoing complete resection of a histologically benign, unilateral, sporadic tumor. A discussion on the importance of lifelong follow-up for patients undergoing surgery for pheochromocytoma follows this cas...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF00311651
更新日期：1996-01-01 00:00:00
abstract：:A 77-year-old man presented to our hospital following the sudden onset of left subclavicular swelling, 8 years after undergoing subtotal removal of an axillofemoral bypass. Computed tomography revealed a rupture of the left axillary artery with the formation of a false aneurysm. Emergency surgery was performed in the ...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF00941818
更新日期：1997-01-01 00:00:00
abstract：:Congenital coronary artery fistulas account for only 0.27%-0.4% of all congenital cardiac defects. We report a case of a right coronary artery (RCA) to a right ventricular(RV) fistula found in 14-year-old girl with clinical signs of heart failure. Echocardiography and cardiac catheterization showed the fistula and a d...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-006-3425-0
更新日期：2007-01-01 00:00:00
abstract：:Malignant fibrous histiocytoma occurs most commonly in the extremities and trunk, but rarely in the visceral organs. Malignant fibrous histiocytoma of the small intestine is an extremely rare condition. To our knowledge, only ten cases of primary tumors involving the small intestine have been described up to now. Amon...
journal_title：Surgery today
pub_type： 杂志文章,评审
doi：10.1007/s005950200221
更新日期：2002-01-01 00:00:00
abstract：:Pancreatic cancer frequently causes extrahepatic cholestasis. To identify the direct effects of bile acids in jaundiced serum on pancreatic cancer, the proliferation of PANC-1 and MIA PaCa-2 cells as well as the ultrastructural alteration of PANC-1 cells cultured in crude bile modified media were studied. The growth o...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s005950070042
更新日期：2000-01-01 00:00:00
abstract：:For vascular occlusive disease, an autologous vein graft is the most suitable conduit for arterial reconstruction. Intimal hyperplasia, resulting from the migration and proliferation of vascular smooth muscle cells, is a major obstacle to patency after vein grafting. The degree to which the function of nitric oxide (N...
journal_title：Surgery today
pub_type： 杂志文章,评审
doi：10.1007/s00595-013-0555-z
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:We previously reported a higher frequency of c-Met protein expression and high proliferative status in gastric cancers producing alpha-fetoprotein (AFP) than in those not producing AFP. METHODS:To investigate this further, we established an AFP-producing gastric cancer cell line, designated as AME-1, from the ...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-003-2668-2
更新日期：2004-01-01 00:00:00
abstract：:Abdominal incisional hernias represent the most common wound complication after abdominal surgery and infected abdominal incisional hernias are difficult to manage. We describe a simple, safe and effective method of using a free fascia lata patch to repair a large infected incisional hernia. This procedure involves th...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-014-0936-y
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:There are an increasing number of reports concerning mitral valve repair by a reconstruction of the chordae tendinae using expanded polytetrafluoro-ethylene (PTFE) sutures. However, little information is available about extended application or results of this technique for an extended prolapse of the anterior m...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-005-3043-2
更新日期：2005-01-01 00:00:00
abstract：:The prognosis for advanced gastrointestinal stromal tumor (GIST) is poor. However, recent reports from Europe have described the effects of imatinib against metastatic GIST. We herein report the case of a Japanese patient treated with imatinib for advanced GIST. Imatinib at 400 mg daily was given to an adult with mult...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-004-2890-6
更新日期：2005-01-01 00:00:00
abstract：:This study was undertaken to determine whether or not the prostanoid metabolism contributes to peritonitis-induced early liver oxidant stress. Lipid peroxidation products, malondialdehyde (MDA) and conjugated dienes (CD), were used to monitor oxidant stress. The rats were given a 5-cc intraperitoneal (i.p.) injection ...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF02482968
更新日期：1999-01-01 00:00:00
abstract：:A postoperative pseudoaneurysm is a rare complication that is difficult to diagnose. Computed tomography (CT) revealed a pseudoaneurysm in the ascending aorta of a 68-year-old female 8 days after mitral valve replacement and tricuspid annuloplasty. The defect was simply repaired during emergency surgery without cardio...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-012-0194-9
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:Managing postoperative pain is important to ensure a good quality of life and fast recovery after surgery. We examined the feasibility of peroral management for the postoperative pain after laparoscopic-assisted distal gastrectomy (LADG). METHODS:Between June 2012 and September 2013, we enrolled 34 patients pr...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-015-1155-x
更新日期：2016-01-01 00:00:00
abstract：:We report a case of acute necrotizing pancreatitis after extraperitoneal repair of an abdominal aortic aneurysm (AAA). Acute pancreatitis (AP) is an uncommon complication of vascular surgery; however, managing its local and general consequences, including the eventual pancreatic abscess and the risk of prosthetic infe...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-007-3668-4
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:The impact of neoadjuvant therapy (NAT) for rectal cancer on lymph node yield is not well known. This study evaluates the impact of NAT on tumor regression and lymph node harvest. METHODS:The subjects were 40 patients with rectal cancer; 20 receiving high-dose, long-course neoadjuvant therapy, and 20 age- and ...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-004-2956-5
更新日期：2005-01-01 00:00:00
abstract：:There have been no reported cases of xanthogranulomatous cholecystitis with a liver abscess and metastatic endophthalmitis in the literature. There has been only one other case of xanthogranulomatous cholecystitis associated with a liver abscess in Japan prior to the present report. A 53-year-old man was admitted to a...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s005950200038
更新日期：2002-01-01 00:00:00
abstract：:We developed a new technique for partial resection of the head of the pancreas with an end-to-side pancreaticoduodenostomy, while preserving the duodenum, the common bile duct, and the upper part of the head of the pancreas around the duct of Santorini. A resection of the inferior head of the pancreas was performed in...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF00311672
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:Acute appendicitis has been suggested to be more aggravated in hemodialysis (HD) patients in comparison to non-HD patients but only scanty evidence demonstrates the conditions. METHODS:A retrospective cohort study was done for HD and non-HD patients with a discharge diagnosis of acute appendicitis in a single ...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-012-0349-8
更新日期：2013-09-01 00:00:00
abstract：:We report a case of adenomyoma in the small intestine, which is an extremely rare entity. An 81-year-old woman presented to our hospital with a history of three episodes of vomiting accompanied by abdominal pain. Upper gastrointestinal examination via a long tube found intestinal obstruction caused by a tumor of the s...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-010-4413-y
更新日期：2011-08-01 00:00:00
abstract：:An experimental study was conducted using a canine model to elucidate whether the once transected vagal nerve can be conveniently anastomosed, and to determine when and to what degree the vagorrhaphy retains its functions. In the vagorrhaphy group (n = 5), the anterior and posterior vagal trunks were transected 1.5 cm...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/BF02384988
更新日期：1997-01-01 00:00:00
abstract：:We experienced a very rare case of male intracystic breast carcinoma. A 66-year-old man presented at our hospital because of a palpable mass in his right breast. The imaging diagnosis was an intracystic carcinoma with hemorrhagic fluid and two mural nodules. Modified radical mastectomy was performed under general anes...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s005950170052
更新日期：2001-01-01 00:00:00
abstract：:Aortoenteric fistula is a rare complication in abdominal aortic aneurysms (AAA), and an aortovesical fistula is even more rare. This is a report of a case of aortocolic and aortovesical fistulae in a 64-year-old man with AAA who was treated with an aortobiiliac bypass, a primary repair of the fistulated bladder, and a...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s10595-002-2510-3
更新日期：2003-01-01 00:00:00
abstract：:An extremely rare case of a lymphoepithelial cyst (LEC) of the pancreas is described herein. A pancreatic cystic tumor was initially detected in a 50-year-old man at a medical checkup. On admission, his serum carbohydrate antigen (CA) 19-9 level was 8100 U/ml and a computed tomography scan revealed a well-circumscribe...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s005950070074
更新日期：2000-01-01 00:00:00
abstract：:Open heart surgery in patients with Child-Pugh class C liver cirrhosis has a high mortality rate and is generally considered to be contraindicated. A patient with liver cirrhosis (Child-Pugh class C) underwent mandatory complex open heart surgery due to severe heart failure. The perioperative management, including the...
journal_title：Surgery today
pub_type： 杂志文章
doi：10.1007/s00595-012-0325-3
更新日期：2013-03-01 00:00:00
