Abstract:
:For vascular occlusive disease, an autologous vein graft is the most suitable conduit for arterial reconstruction. Intimal hyperplasia, resulting from the migration and proliferation of vascular smooth muscle cells, is a major obstacle to patency after vein grafting. The degree to which the function of nitric oxide (NO) in the vein graft is preserved has been reported to be associated with the magnitude of intimal hyperplasia. Serotonin (5-HT) is released from platelets in the vascular system and plays physiological roles in controlling the vascular tone. The subtype receptors contributing to the 5-HT-induced mechanical responses vary by vessel type (artery and vein) and among species (dogs, rabbits, rats, and so on). Recent studies have demonstrated that 5-HT induces vasoconstriction through the activation of 5-HT2A receptors in smooth muscle cells or vasodilatation through the activation of endothelial 5-HT1B receptors in arteries from various animals. However, the effects of 5-HT have not been clarified in grafted veins. We herein demonstrate the responses to 5-HT in un-operated veins and then autogenous vein grafts. Next, we describe the effects of chronic in vivo administration of Rho-kinase inhibitors and 5-HT2A receptor antagonists, both of which reduce the 5-HT-induced contraction and intimal hyperplasia in vein grafts. Further studies targeting 5-HT are required to evaluate its possible benefits for autologous vein grafts with respect to vasospasm, function, and patency.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Kodama A,Itoh T,Komori Kdoi
10.1007/s00595-013-0555-zsubject
Has Abstractpub_date
2014-02-01 00:00:00pages
213-8issue
2eissn
0941-1291issn
1436-2813journal_volume
44pub_type
杂志文章,评审相关文献
SURGERY TODAY文献大全abstract::Laparoscopic splenectomy is now established as a safe and feasible procedure. However, it remains associated with some short- and long-term postoperative complications, especially infectious complications. To our knowledge, this is the first report (with video) focusing on the safety and feasibility of laparoscopic he...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-018-1639-6
更新日期:2018-07-01 00:00:00
abstract::This study was conducted to examine the effectiveness of the double-stapling technique (DST) for performing esophageal anastomoses. A total of 17 patients, 10 with esophageal cancer and 7 with gastric cancer, underwent esophageal anastomosis employing this technique. Of the ten patients who underwent esophageal operat...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00312390
更新日期:1995-01-01 00:00:00
abstract::Papillary adenocarcinoma is extremely rare in the squamous epithelium-lined esophagus. The histopathologic and immunohistochemical characteristics were examined in a composite tumor showing distinct papillary adenocarcinoma and squamous cell carcinoma of the esophagus resected from a 66-year-old man. The esophageal tu...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950050601
更新日期:2000-01-01 00:00:00
abstract::We report herein an extremely rare case of retroperitoneal neuroblastoma occurring in a mother during her third trimester of pregnancy. A live male infant was delivered by cesarean section at 36 weeks gestation and 23 days later, the mother's tumor was curatively resected. Six months have elapsed since her operation a...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311716
更新日期:1993-01-01 00:00:00
abstract::Bone loss and the serum markers of bone metabolism were studied in 22 patients with primary hyperparathyroidism and 108 patients with renal hyperparathyroidism. The parameters of bone loss were bone mineral density in the distal radius and lumbar vertebrae, measured by dual energy X-ray absorptiometry, and bone mass i...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311432
更新日期:1995-01-01 00:00:00
abstract::We present herein the case of a pyogenic liver abscess developing from hepatic ischemia caused by resection of the right hepatic artery when a left hemihepatectomy with caudate lobectomy and extrahepatic bile duct resection was performed for cholangiocellular carcinoma. Postoperative cholangiography revealed communica...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF01833737
更新日期:1994-01-01 00:00:00
abstract::Recently we encountered two cases of early gastric cancer (EGC) with bone metastasis after surgery. As they were not accompanied by overt liver, lung, or peritoneal metastasis, we examined the clinical significance of bone metastasis in EGC and its mechanisms by a review of the literature. We found only 10 cases of EG...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-010-4389-7
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To assess the diagnostic value of the white blood cell count (WBC) and serum C-reactive protein (CRP) level in children with advanced appendicitis. METHODS:We reviewed 289 children ranging in age from 3 to 15 years old, who underwent appendectomy in our hospital between 1993 and 2003. The advanced appendicitis...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-006-3189-6
更新日期:2006-01-01 00:00:00
abstract::We report a case that was successfully treated by primary stent placement without thrombolysis or thrombectomy for graft thrombosis after aortoiliac reconstructive surgery. A 79-year-old man presented with a 2-month history of severe intermittent claudication of the right leg. He had undergone a surgical repair of abd...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-008-3855-y
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:The aim of this study is to evaluate the association between the participation of board-certified surgeons in gastroenterological surgery (BCS-Gs) and the surgical outcomes of gastroenterological surgery. METHODS:Data from the National Clinical Database on patients who underwent eight major gastroenterological...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-016-1422-5
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To validate the usefulness of sennoside as a substitute for polyethylene glycol (PEG) as a mechanical bowel preparation (MBP) for elective colon cancer surgery. METHODS:We performed a prospective randomized non-inferiority trial comparing the use of sennoside and PEG in MBP for elective colon cancer surgery, i...
journal_title:Surgery today
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00595-015-1239-7
更新日期:2016-06-01 00:00:00
abstract:PURPOSES:Preoperative chemoradiation is a potential treatment option for localized gastric adenocarcinoma (GAC). Currently, the response to chemoradiation cannot be predicted. We analyzed the pretreatment maximum standardized uptake value (SUVmax) and total lesion glycolysis (TLG) on positron emission tomography/comput...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-020-02018-2
更新日期:2020-10-01 00:00:00
abstract::Presented herein is the case of a 27-year-old man in whom an endobronchial tumor was found causing complete obstruction of the left main bronchus. The tumor was successfully removed by performing sleeve resection of the left main bronchus without pulmonary resection, immediately following which the left lung became re...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311091
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:Laparoscopic sleeve gastrectomy (SG) has gained popularity and acceptance among bariatric surgeons, mainly due its low morbidity and mortality. The purpose of the present study was to evaluate the efficacy of SG on weight loss, and to determine the postoperative course, clinical presentation and treatment of co...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0688-0
更新日期:2014-07-01 00:00:00
abstract::In a 61-year-old woman who underwent extensive retroperitoneal lymph node dissection for rectal cancer, postoperative chylous ascites developed. The site of the lymphatic leak was evident on the lymphangiogram with lipiodol taken prior to the surgical repair of the leak, and another site seen on the intraoperative lym...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311375
更新日期:1993-01-01 00:00:00
abstract::We herein report a rare case of cardiac and abdominal aortic inflammatory pseudotumors (IPTs). A 64-year-old male presented with a loss of appetite, abdominal distension and general fatigue. A cardiac tumor was suspected on the basis of computed tomography scans. A needle biopsy was performed, but it did not lead to a...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0780-5
更新日期:2015-02-01 00:00:00
abstract::We recently reported the balance of T helper type 1 (Th1) cells and type 2 (Th2) cells in patients with lung carcinomas. This study was conducted to investigate their activity and role in tumors, which remain unclear. We determined the population of lymphocytes with intracellular interferon (IFN)-gamma or interleukin ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950170127
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To classify the shape of the remnant stomach after Billroth-I (B-I) reconstruction and evaluate the relationship between the shape of the remnant stomach and the postoperative clinical outcomes. METHODS:One hundred and ninety-five consecutive patients with gastric cancer underwent distal gastrectomy with B-I r...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-018-1676-1
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Papillary thyroid carcinoma (PTC) frequently metastasizes to and recurs in regional lymph nodes. Of the two compartments, the central compartment can be dissected through the same wound as the thyroidectomy, and the central node dissection (CND) is routinely performed in most Japanese surgical departments. Howe...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4494-7
更新日期:2011-11-01 00:00:00
abstract::A tissue biopsy is the "golden standard" for molecular profiling that is essential in decision-making regarding treatment for malignant tumors, including primary lung cancer. However, tumor biopsies are associated with several limitations, including invasiveness and difficulty in achieving access. Liquid biopsies have...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-018-1659-2
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:We examined the impact of advanced age on left ventricular mass regression and the change in the diastolic function after aortic valve replacement in patients with aortic stenosis. METHODS:The present study included 129 patients who underwent either surgical or transcatheter aortic valve replacement and 1-year...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-016-1458-6
更新日期:2017-06-01 00:00:00
abstract::Two types of tumor necrosis factor membrane receptors (TNF-R) have been identified, namely 55 and 75 kDa TNF-R. Soluble forms of these receptors are present in the human serum. Recent findings on the role of these two TNF-R in biological cell signaling and the clinical significance of the serum levels of soluble TNF-R...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/BF02032887
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Several recent studies have evaluated the feasibility of the sentinel node (SN) concept for gastric cancer. The aim of our study was to investigate limited gastrectomy with SN basin dissection in SN navigation surgery (SNNS) for patients with early-gastric cancer located in the upper-third of the stomach. METH...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-019-1768-6
更新日期:2019-06-01 00:00:00
abstract::A postoperative pseudoaneurysm is a rare complication that is difficult to diagnose. Computed tomography (CT) revealed a pseudoaneurysm in the ascending aorta of a 68-year-old female 8 days after mitral valve replacement and tricuspid annuloplasty. The defect was simply repaired during emergency surgery without cardio...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-012-0194-9
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:We evaluated the technical and oncological safety of laparoscopic multivisceral resection (MVR) in selected patients with locally advanced colon cancer (LACC). METHODS:We compared the clinical backgrounds, and short- and long-term outcomes of patients who underwent laparoscopic vs. those who underwent open MVR...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-020-01986-9
更新日期:2020-09-01 00:00:00
abstract::Between June 1991 and February 1999, three patients suffered ascending aortic dissection as a complication of cardiopulmonary bypass operations with aortic cannulation at our hospital. The dissection occurred during the operation in two of the three patients and several months after the operation in one. Among a total...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950070026
更新日期:2000-01-01 00:00:00
abstract::The improvement of heart function in a patient on hemodialysis with dilated cardiomyopathy by renal transplantation is herein reported. The patient was a 35-year-old woman. Hemodialysis had been initiated 3 months before, but she experienced difficulty with hemodialysis maintenance and exhibited congestive heart failu...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00308977
更新日期:1993-01-01 00:00:00
abstract::Thoracic esophageal cancers frequently metastasize to the right recurrent nerve nodes (RRNNs). In fact, huge RRNNs invading the trachea sometimes remain after definitive chemoradiation therapy (CRT), despite complete remission of the primary lesion. We performed salvage lymphadenectomy of a large RRNN combined with pa...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-006-3447-7
更新日期:2007-01-01 00:00:00
abstract::This report presents the case of a common hepatic artery (CHA) pseudoaneurysm secondary to postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD), which was successfully treated using a coronary covered stent. A 70-year-old female underwent subtotal stomach-preserving PD for middle cholangiocarcinoma...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-012-0314-6
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To define the outcomes of our original simple chordal replacement technique using ePTFE sutures for mitral regurgitation. METHODS:Between January, 2004 and March, 2014, 38 patients underwent mitral valve repair using our chordal replacement technique for anterior leaflet prolapse. The mitral regurgitation was ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-018-1745-5
更新日期:2019-04-01 00:00:00