The association of cigarette smoking with a high risk of recurrence after ileocolonic resection for ileocecal Crohn's disease.

Abstract:

:The purpose of this retrospective study was to examine the influence of cigarette smoking on the recurrence of Crohn's disease after resection. Between 1975 and 1990, 141 patients underwent primary ileocolonic resection for ileocecal Crohn's disease, 79 of whom were nonsmokers and 62 of whom were smokers at the time of their operation. The 5- and 10-year cumulative recurrence-free rates were 65% and 45% for the smokers, and 81% and 64% for the nonsmokers, the former values being significantly lower than the latter values (P = 0.007). The smokers were further divided into two subgroups according to the number of cigarettes smoked per day; as mild smokers who smoked fewer than 15 per day (n = 31) and heavy smokers who smoked 15 or more per day (n = 31). The cumulative recurrence-free rate was lower in the heavy smokers compared with the mild smokers. These findings strongly suggest that smoking is associated with a high recurrence rate after ileocolonic resection for ileocecal Crohn's disease.

journal_name

Surg Today

journal_title

Surgery today

authors

Yamamoto T,Keighley MR

doi

10.1007/BF02482360

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

579-80

issue

6

eissn

0941-1291

issn

1436-2813

pii

10.1007/BF02482360

journal_volume

29

pub_type

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