Anti-immunoglobulin e in the treatment of refractory atopic dermatitis.

Abstract:

:Atopic dermatitis (AD) is a common diagnosis seen in both children and adults, and it is often the first manifestation of atopic disease. Research has shown a strong correlation between serum IgE levels, the severity of atopic dermatitis, and co-existing asthma and/or allergic rhinitis. Omalizumab (Xolair, East Hanover, NJ; Genentech, South San Francisco, CA) is a monoclonal antibody to human IgE and is currently Food and Drug Administration (FDA) approved for the treatment of asthma. We present 3 patients with severe, treatment resistant atopic dermatitis whose cutaneous symptoms significantly improved by treatment with omalizumab.

journal_name

South Med J

journal_title

Southern medical journal

authors

Amrol D

doi

10.1097/SMJ.0b013e3181de0cf6

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

554-8

issue

6

eissn

0038-4348

issn

1541-8243

pii

00007611-201006000-00016

journal_volume

103

pub_type

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