当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > Cerebro- and cardiovascular reactivity and neuropsychological performance in hypertensive patients.

Cerebro- and cardiovascular reactivity and neuropsychological performance in hypertensive patients.

Abstract：

BACKGROUND:Hypertensive (HT) patients are at higher risk of cognitive decline than normotensive individuals, because high blood pressure is a risk factor for mild cognitive deterioration. In this study cardio- and cerebrovascular reactivity along with cognitive performance was assessed on newly diagnosed HT patients. METHODS:Diagnosis of hypertension was based on international recommendations. None of the patients had diabetes, and all of them had normal cerebral CT scan. Eighty-one patients (43.5±10.2 years, male/female ratio: 42/39) were compared with 94 healthy controls (44±9.4 years, male/female ratio: 50/44). In both groups continuous, non-invasive and simultaneous monitoring of cerebral and cardiac hemodynamical parameters were recorded during head-up tilt table testing (HUTT). Reaction time, attention and memory skills, anxiety and depression rate were determined by neuropsychological tests. RESULTS:During HUTT significant differences were found in certain cardiovascular parameters (blood pressure, total peripheral resistance index, stroke index), but no differences were detected in cerebral blood flow velocity. While there was no significant difference in reaction time between the two groups, tests estimating short-term memory (Digit Span Test) differed significantly. Moreover, sum of standardized test scores was significantly lower, while anxiety level was significantly increased in HT patients compared to controls. CONCLUSION:Decrease in neuropsychological performance along with alterations of cardiovascular parameters is an early manifestation of hypertension. Aim for an early intervention and accurate treatment is crucial for preventing further impairments.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Kovács KR,Szekeres CC,Bajkó Z,Csapó K,Molnár S,Oláh L,Magyar MT,Bereczki D,Kardos L,Soltész P,Bojtor AB,Csiba L

doi

10.1016/j.jns.2010.07.022

subject

Has Abstract

pub_date

2010-12-15 00:00:00

pages

120-5

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(10)00345-X

journal_volume

299

pub_type

杂志文章

相关文献

JOURNAL OF THE NEUROLOGICAL SCIENCES文献大全
  • Cytokine and chemokine mRNA expressing cells in muscle tissues of experimental autoimmune myasthenia gravis.

    abstract：:In-situ hybridization with labeled oligonucleotide probes was applied to explore cytokine and chemokine mRNA expression in sections of striated muscle, the target organ in experimental autoimmune myasthenia gravis (EAMG), induced in Lewis rats by immunization with acetylcholine receptor (AChR) and complete Freund's ad...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(98)00181-6

    authors： Li H,Shi FD,Bai X,Huang Y,Diab A,He B,Link H

    更新日期：1998-11-26 00:00:00

  • Preimplantation factor (PIF*) reverses neuroinflammation while promoting neural repair in EAE model.

    abstract：INTRODUCTION:Embryo-derived PIF modulates systemic maternal immunity without suppression. Synthetic analog (sPIF) prevents juvenile diabetes, preserves islet function, reducing oxidative stress/protein misfolding. We investigate sPIF effectiveness in controlling neuroinflammation/MS. METHODS:Examine sPIF-induced prote...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.07.050

    authors： Weiss L,Or R,Jones RC,Amunugama R,JeBailey L,Ramu S,Bernstein SA,Yekhtin Z,Almogi-Hazan O,Shainer R,Reibstein I,Vortmeyer AO,Paidas MJ,Zeira M,Slavin S,Barnea ER

    更新日期：2012-01-15 00:00:00

  • Sleep structure and nocturnal disordered breathing in familial dysautonomia.

    abstract：:In 13 patients with familial dysautonomia sleep recordings were obtained to investigate the possibility that autonomic nervous system dysfunction plays a role in disordered breathing during sleep. Sleep structure in some of our patients was abnormal, showing decreased amount of REM sleep and increased REM latencies. A...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(83)90131-4

    authors： Gadoth N,Sokol J,Lavie P

    更新日期：1983-07-01 00:00:00

  • PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden.

    abstract：BACKGROUND:Genetic variants in Phosphodiesterase 4D (PDE4D) and 5-lipoxygenase activating protein (ALOX5AP) have been shown to confer risk of Ischemic Cerebrovascular Disease (ICVD) in Iceland. We investigated whether these variants associate with ICVD in Sweden. METHODS:Previously published PDE4D and ALOX5AP gene var...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2007.06.042

    authors： Kostulas K,Gretarsdottir S,Kostulas V,Manolescu A,Helgadottir A,Thorleifsson G,Gudmundsson LJ,Thorsteinsdottir U,Gulcher JR,Stefansson K,Hillert J

    更新日期：2007-12-15 00:00:00

  • Infectious aneurysm of the intracavernous carotid artery occurring concomitantly with sphenoid sinusitis; an autopsy case report.

    abstract：:A previously healthy 56-year-old woman presented with right-sided ophthalmic pain and diplopia following headache and fever. A neurological examination revealed 3rd and 6th right cranial nerve palsies. Brain magnetic resonance imaging (MRI) and 3D-computed tomography (CT) angiography (CTA) showed right-sided sphenoid ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2008.11.017

    authors： Sugie M,Ihihara K,Nakano I,Kawamura M

    更新日期：2009-03-15 00:00:00

  • Deprenyl enhances neurite outgrowth in cultured rat spinal ventral horn neurons.

    abstract：:Deprenyl, a selective monoamine oxidase B inhibitor, is effective in Parkinson's disease, and can slow the cognitive deterioration in Alzheimer's disease. However, it is not known whether this agent has a trophic effect on spinal motor neurons. We have studied neurotrophic effects of deprenyl on spinal motor neurons, ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(94)90235-6

    authors： Iwasaki Y,Ikeda K,Shiojima T,Kobayashi T,Tagaya N,Kinoshita M

    更新日期：1994-08-01 00:00:00

  • The "posture second" strategy: a review of wrong priorities in Parkinson's disease.

    abstract：:Falls are common in Parkinson's disease. It remains difficult to predict these falls, presumably because clinical balance tests assess single components of postural control, whereas everyday fall mechanisms are typically more complicated. A substantial proportion of everyday falls appears to occur while Parkinson pati...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2006.05.010

    authors： Bloem BR,Grimbergen YA,van Dijk JG,Munneke M

    更新日期：2006-10-25 00:00:00

  • Formononetin mediates neuroprotection against cerebral ischemia/reperfusion in rats via downregulation of the Bax/Bcl-2 ratio and upregulation PI3K/Akt signaling pathway.

    abstract：:Isoflavone formononetin is a typical phytoestrogen isolated from Chinese medical herb red clover. It has been reported that estrogens have neuroprotective properties, and dietary intake of phytoestrogens could reduce stroke injury in cerebral ischemia/reperfusion (I/R) animal models. In the present research, we sought...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.06.033

    authors： Liang K,Ye Y,Wang Y,Zhang J,Li C

    更新日期：2014-09-15 00:00:00

  • Usage of SWI (susceptibility weighted imaging) acquired at 7T for qualitative evaluation of temporal lobe epilepsy patients with histopathological and clinical correlation: An initial pilot study.

    abstract：OBJECTIVES:Ultra high field MRI at 7T is able to provide much improved spatial and contrast resolution which may aid in the diagnosis of hippocampal abnormalities. This paper presents a preliminary experience on qualitative evaluation of 7T MRI in temporal lobe epilepsy patients with a focus on comparison to histopatho...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.07.066

    authors： Kwan BYM,Salehi F,Ohorodnyk P,Lee DH,Burneo JG,Mirsattari SM,Steven D,Hammond R,Peters TM,Khan AR

    更新日期：2016-10-15 00:00:00

  • Selective type II fibre muscular atrophy in patients with osteoarthritis of the hip.

    abstract：:The size and the distribution of type I and tye II fibres was determined in the gluteus maximus (21 cases), gluteus medius (56 cases) and tensor faciae latae (27 cases) muscles of patients with osteoarthritis of the hip. The patients were of both sexes, aged between 37 and 64 years (younger group) and between 65 and 7...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(80)90123-9

    authors： Sĭrca A,Susec-Michieli M

    更新日期：1980-01-01 00:00:00

  • Blood pressure variability and outcome after acute intracerebral hemorrhage.

    abstract：:Intracerebral hemorrhage (ICH) is life threatening neurologic event that results in significant rate of morbidity and mortality. Unfortunately, several randomized clinical trials aiming at limiting the hematoma expansion (HE) in the acute phase of ICH have not shown significant effects in improving the functional outc...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2020.116766

    authors： Jafari M,Damani R

    更新日期：2020-06-15 00:00:00

  • Sixth nerve palsy associated with obstruction in Dorello's canal, accompanied by nodular type muscular sarcoidosis.

    abstract：:A 52-year-old Japanese woman complaining of horizontal double vision for 10 days was admitted to our hospital. Neurological examination revealed left abducent nerve palsy and muscle swelling in her thighs. Brain MRI showed obstruction in the spinal fluid space of the left Dorello's canal, which transmits a portion of ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.05.055

    authors： Shioya A,Takuma H,Shiigai M,Ishii A,Tamaoka A

    更新日期：2014-08-15 00:00:00

  • Anatomical basis for a parasympathetic and sensory innervation of the intracranial segment of the internal carotid artery in man. Possible implication for vascular headache.

    abstract：:Two ganglionic cell groups, located close together and called the internal carotid ganglion, not described before in man, were demonstrated extradurally on the ventrolateral surface of the human internal carotid artery (ICA), where the greater superficial petrosal nerve is joined by the (greater) deep petrosal nerve t...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(91)90211-o

    authors： Suzuki N,Hardebo JE

    更新日期：1991-07-01 00:00:00

  • Impaired modulation of tonic muscle activities and H-reflexes in the soleus muscle during standing in patients with Parkinson's disease.

    abstract：:The presence of postural disturbance in patients with Parkinson's disease (PD) was assessed by the displacement of the centre of foot pressure (CFP) and by changes in the amplitude of the soleus H-reflex when patients maintained an upright standing posture, followed by a forward-leaning posture. Thirteen patients and ...

    journal_title：Journal of the neurological sciences

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0022-510x(97)00175-5

    authors： Hayashi R,Tokuda T,Tako K,Yanagisawa N

    更新日期：1997-12-09 00:00:00

  • Progressive aphemia in a patient with Pick's disease: a neuropsychological and anatomic study.

    abstract：:We describe a patient with progressive aphemia with agrammatism that was later overlaid with buccofacial apraxia and pseudobulbar palsy. Pathological findings were consistent with those of classic Pick's disease with argyrophilic inclusions and neuronal achromasia, except for restricted cortical atrophy in the frontal...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(98)00159-2

    authors： Sakurai Y,Murayama S,Fukusako Y,Bando M,Iwata M,Inoue K

    更新日期：1998-08-14 00:00:00

  • Imaging correlates of apathy and depression in Parkinson's disease.

    abstract：:Though the core symptoms of Parkinson's disease (PD) are motor-related, a majority of patients also have neuropsychiatric symptoms concerning mood, behavior and cognition. Apathy and depression are considered among the most frequent ones, and have a negative impact on global functioning and quality of life. Recent neu...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2011.07.006

    authors： Benoit M,Robert PH

    更新日期：2011-11-15 00:00:00

  • Changes in the clinical phenotypes of multiple sclerosis during the past 50 years in Japan.

    abstract：:In order to clarify whether or not marked changes in the social environment during the past 50 years in Japan may have altered the clinical phenotypes of multiple sclerosis (MS), we retrospectively analyzed 143 consecutive patients with clinically definite MS who developed the disease between 1950 and 1997. Fifty-two ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(99)00115-x

    authors： Kira J,Yamasaki K,Horiuchi I,Ohyagi Y,Taniwaki T,Kawano Y

    更新日期：1999-06-15 00:00:00

  • Expression of RGMb in brain tissue of MCAO rats and its relationship with axonal regeneration.

    abstract：OBJECTIVE:To investigate the changes in the expression of repulsive guidance molecule b (RGMb) in brain tissue of rats with ischemic cerebral infarction and determine its relationship with axonal regeneration, synapse remodeling and magnetic resonance imaging (MRI) parameters with magnetic resonance diffusion tensor im...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.10.032

    authors： Wang X,Cheng JL,Ran YC,Zhang Y,Yang L,Lin YN

    更新日期：2017-12-15 00:00:00

  • Adult-onset leukodystrophy with axonal spheroids.

    abstract：:We report two cases of adult-onset leukodystrophy with axonal spheroids in a brother and sister, one with an autopsy, the other with a cerebral biopsy. Symptoms developed at 24 and 33years. The sister died within four years, her brother in 2 and a half. Her brain showed a large lesion in the frontal centrum semiovale ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.06.027

    authors： Mendes A,Pinto M,Vieira S,Castro L,Carpenter S

    更新日期：2010-10-15 00:00:00

  • Machado-Joseph disease in three Scandinavian families.

    abstract：:Machado-Joseph disease (MJD) is an autosomal dominantly inherited neurodegenerative disorder characterized by varying age of onset and pronounced phenotypic heterogeneity. The clinical core features include gait ataxia, external ophthalmoplegia, nystagmus, and bulging eyes. Recently, Kawagushi et al. (1994) cloned the...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(98)00081-1

    authors： Løkkegaard T,Nielsen JE,Hasholt L,Fenger K,Werdelin L,Tranebjaerg L,Lauritzen M,Colding-Jørgensen E,Grønbech-Jensen M,Henriksen OA,Sørensen SA

    更新日期：1998-04-01 00:00:00

  • Propriospinal myoclonus associated with gluten sensitivity in a young woman.

    abstract：:Propriospinal myoclonus (PSM) is a rare movement disorder characterized by involuntary axial jerks originating from muscles innervated by multiple spinal segments. Most cases of PSM are idiopathic. Gluten sensitivity is a multisystemic autoimmune condition which may be associated with various neurological disorders, m...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.12.004

    authors： Zhang Y,Menkes DL,Silvers DS

    更新日期：2012-04-15 00:00:00

  • Human cerebrospinal fluid somatostatin in neurologic disease.

    abstract：:Concentrations of somatostatin-like immunoreactivity (SLI) were examined in human cerebrospinal fluid (CSF). To validate the assay it was shown that CSF which had been run over a somatostatin immunoaffinity column showed no interference with binding of synthetic standards. Reversed phase HPLC showed that the immunorea...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(85)90039-5

    authors： Beal MF,Mazurek MF,Black PM,Martin JB

    更新日期：1985-11-01 00:00:00

  • LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor.

    abstract：:Leucine-rich repeats and immunoglobulin-like domains (LRIG) 3 gene is mapped to chromosome 12q13.2, a region that is frequently deleted in a subset of glioblastoma multiforme (GBM). It has been reported that perinuclear LRIG3 staining correlated with low WHO grade of glioma and better survival of the patients. However...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.02.015

    authors： Guo D,Yang H,Guo Y,Xiao Q,Mao F,Tan Y,Wan X,Wang B,Lei T

    更新日期：2015-03-15 00:00:00

  • Neuroprotection induced by sevoflurane-delayed post-conditioning is attributable to increased phosphorylation of mitochondrial GSK-3β through the PI3K/Akt survival pathway.

    abstract：BACKGROUND AND PURPOSE:Post-conditioning with volatile anesthetics can create ischemic tolerance against cerebral ischemia-reperfusion injury. The present study was designed to determine whether delayed exposure to sevoflurane could induce ischemic tolerance and if this effect was dependent on increasing phosphorylated...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.12.011

    authors： Ye Z,Xia P,Cheng ZG,Guo Q

    更新日期：2015-01-15 00:00:00

  • Peroneal muscular atrophy. Part 2. Nerve biopsy studies.

    abstract：:The present study used the nerve pathology, studied by quantitative light microscopy, as the sole basis for classification of peroneal muscular atrophy (PMA). The findings in biopsies of superficial peroneal nerves of 20 patients were compared with normal values obtained from 8 controls. Three homogeneous groups compr...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(83)90173-9

    authors： Gherardi R,Bouché P,Escourolle R,Hauw JJ

    更新日期：1983-10-01 00:00:00

  • Are white matter abnormalities associated with "unexplained dizziness"?

    abstract：INTRODUCTION:Although cerebral small vessel disease is a significant contributor to the development of imbalance and falls in the elderly, whether it causes dizziness is not known. METHODS:A retrospective case analysis was conducted for 122 dizzy patients referred to two neuro-otology tertiary centres in London and Pi...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.jns.2015.09.006

    authors： Ahmad H,Cerchiai N,Mancuso M,Casani AP,Bronstein AM

    更新日期：2015-11-15 00:00:00

  • Myopathy with hyperaldosteronism. An electron-microscopic study.

    abstract：:In the case reported, an overproduction of aldosterone was accompanied by paretic attacks, a decrease in the serum potassium level, and in muscle tone and the deep tendon reflexes. The decrease of serum potassium level was consistent, but moderate, being to just below the normal lower limit. Loading with carbohydrate ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(77)90017-x

    authors： Gallai M

    更新日期：1977-07-01 00:00:00

  • French translation and normation of the Parkinson Neuropsychometric Dementia Assessment (PANDA).

    abstract：INTRODUCTION:Cognitive impairment and depressive symptoms caused by Parkinson's disease (PD) are often underestimated in routine clinical practice, partly due to the lack of short screening tests. The "Parkinson Neuropsychometric Dementia Assessment" (PANDA) is a new convenient tool, validated in German, to assess cogn...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.06.044

    authors： Gasser AI,Kalbe E,Calabrese P,Kessler J,Von Allmen G,Rossier P

    更新日期：2011-11-15 00:00:00

  • Rapid eye movement sleep atonia in patients with cognitive impairment.

    abstract：:Acetylcholine (ACh) plays an important role in cognitive function and muscle atonia in rapid eye movement (REM) sleep. This quantitative study used surface electromyography (sEMG) to investigate changes in muscular activity, which may indicate a deficiency of ACh among patients with cognitive impairment. We recruited ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.03.022

    authors： Chen PC,Wu D,Chen CC,Chi NF,Kang JH,Hu CJ

    更新日期：2011-06-15 00:00:00

  • Quantitative examination of internodal length of remyelinated nerve fibres in the central nervous system.

    abstract：:The internodal length of remyelinated internodes was examined by observations on teased CNS nerve fibres following primary demyelination induced by intraspinal injections of lysolecithin into the white matter of cats. A remyelinated internode was identified as a thinly-myelinated internode, where a node of Ranvier was...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(81)90084-8

    authors： Blakemore WF,Murray JA

    更新日期：1981-02-01 00:00:00