Blood pressure variability and outcome after acute intracerebral hemorrhage.

Abstract:

:Intracerebral hemorrhage (ICH) is life threatening neurologic event that results in significant rate of morbidity and mortality. Unfortunately, several randomized clinical trials aiming at limiting the hematoma expansion (HE) in the acute phase of ICH have not shown significant effects in improving the functional outcomes. Blood pressure variability (BPV) is common following ICH. High BPs have been associated with increased risk of bleeding and HE. Conversely, recurrent sudden decrease in BP promote perihematomal ischemia. However, it is still not clear weather BPV causes adverse prognosis following ICH or large ICHs cause fluctuations in BP. In the current review, we will discuss the mechanistic pathophysiology of BPV and the evidence regarding the role of BPV on the ICH outcomes.

journal_name

J Neurol Sci

authors

Jafari M,Damani R

doi

10.1016/j.jns.2020.116766

subject

Has Abstract

pub_date

2020-06-15 00:00:00

pages

116766

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(20)30102-7

journal_volume

413

pub_type

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