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Diagnosis and treatment of osteoporosis in spinal cord injury patients: A literature review.

Abstract：

OBJECTIVE:To present an up-to-date literature review of osteoporosis in spinal cord injury (SCI) patients, in view of the seriousness of this complication (with a high risk of fractures) and the complexity of its diagnosis, evaluation and treatment. METHODS:A Medline search with the following keywords: immobilization osteoporosis, spinal cord injury, bone loss, dual energy X-ray absorptiometry (DEXA), bisphosphonate. RESULTS:Our analysis of the literature noted a bone metabolism imbalance in SCI patients, with accelerated early bone resorption (particularly during the first 6 months post-injury). Although dual energy X-ray absorptiometry constitutes the "gold standard" diagnostic method, the decrease in bone mineral density only becomes significant 12 months after the injury. Bisphosphonate therapy has proven efficacy. Despite the frequent use of various physical therapies, these methods have not been found to be effective. CONCLUSION:Although our literature review did not identify any guidelines on the strategy for diagnosing and treating osteoporosis in SCI patients, several findings provide guidance on procedures for early diagnosis and preventive treatment.

journal_name

Ann Phys Rehabil Med

journal_title

Annals of physical and rehabilitation medicine

authors

Charmetant C,Phaner V,Condemine A,Calmels P

doi

10.1016/j.rehab.2010.10.001

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

655-68

issue

10

eissn

1877-0657

issn

1877-0665

pii

S1877-0657(10)00263-0

journal_volume

53

pub_type

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