Abstract:
UNLABELLED:Osteoporosis is a common complication in children with motor impairments. They have a higher risk of fractures (20% during their lifetime) mostly at femoral level. Furthermore, these children have pain yet no clear relation has been established between osteoporosis and pain. The efficacy of bisphosphonates has been validated in adults and for children with osteogenesis imperfecta (OI). However, its use in children with motor impairments has not yet been validated. PATIENTS AND METHODS:Retrospective study on the medical charts of children presenting neurological diseases and motor impairments associated to secondary symptomatic osteoporosis. These children underwent treatment with Pamidronate(®) intravenous infusions (I.V.) in Lyon and Valence between 2002 and 2008. Data were collected on pain control, incidence and frequency of fractures and bone mass density (BMD). Data on adverse events were also collected to evaluate treatment's tolerance. RESULTS:Twelve children's charts were studied for a total of 50 Pamidronate(®) I.V. infusions. Regarding treatment's efficacy, we observed a clear decrease and even total relief of the pain with improvement reported after 98% of perfusions. Regarding BMD, there was a real improvement after the treatment (e.g., lumbar BMD measures, -46.5% before treatment and -27% after treatment). The adverse events, flu-like syndrome, muscle pain and asymptomatic hypocalcemia, were minor and quickly reversible. CONCLUSION:It seems quite essential to screen for osteoporosis-related pain in these children and treat them quickly to avoid a negative impact on their quality of life. Treatment with I.V. bisphosphonates has shown its relevance, yet practical modalities still need to be defined. It would be interesting but quite difficult to implement, in light of the positive effect of this study, a prospective, randomized, controlled, double-blind vs. placebo study on a large enough sample of patients.
journal_name
Ann Phys Rehabil Medjournal_title
Annals of physical and rehabilitation medicineauthors
Wagner S,Poirot I,Vuillerot C,Berard Cdoi
10.1016/j.rehab.2011.07.002subject
Has Abstractpub_date
2011-09-01 00:00:00pages
348-58issue
6eissn
1877-0657issn
1877-0665pii
S1877-0657(11)00095-9journal_volume
54pub_type
杂志文章abstract:BACKGROUND:Locked-in syndrome (LIS) characterizes individuals who have experienced pontine lesions, who have limited motor output but with preserved cognitive abilities. Despite their severe physical impairment, individuals with LIS self-profess a higher quality of life than generally expected. Such third-person expect...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.09.011
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery. Individuals with disorders of consciousness (DOC) classically receive hydration and nutrition through an enteral-feeding tube. However, the r...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2020.04.008
更新日期:2020-07-18 00:00:00
abstract::Sacroiliac joint (SIJ) is an uncommon localisation of osteoarthritis. Instability of this joint is one of rare aetiologies. It can occur after resection of the pubic symphysis for whatever the reason. The biomechanical consequences on the SIJ are increasing shear forces and vertical restrain. This leads to secondary p...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2009.03.002
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVES:Previous research suggested isolated associations of physical and psychological factors with fibromyalgia severity. Integration of physical and psychological, experienced and observed, modifiable factors associated with fibromyalgia severity in a single model will reveal therapeutic paths toward less severit...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.06.017
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Upper-limb robotic-assisted therapy (RAT) is promising for stroke rehabilitation, particularly in the early phase. When RAT is provided as partial substitution of conventional therapy, it is expected to be at least as effective or might be more effective than conventional therapy. Assessments have usually be...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.rehab.2019.04.002
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To present an up-to-date literature review of osteoporosis in spinal cord injury (SCI) patients, in view of the seriousness of this complication (with a high risk of fractures) and the complexity of its diagnosis, evaluation and treatment. METHODS:A Medline search with the following keywords: immobilization ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2010.10.001
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Amyotrophic lateral sclerosis (ALS) has long been considered a pure motor neurodegenerative disease. However, now, extra-motor manifestations such as cognitive-behavioral disorders are considered not rare and are even a severity factor of the disease. Experiencing anosognosia (i.e., the inability to recogniz...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2020.08.004
更新日期:2020-10-13 00:00:00
abstract:BACKGROUND:There is little focus on adults with cerebral palsy (CP) in research and health care and insufficient knowledge on how to identify and manage pain in this population. OBJECTIVES:This systematic review and meta-analysis aimed to determine whether pain prevalence in adults with CP is high and to explore varia...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2019.12.011
更新日期:2020-02-13 00:00:00
abstract::Numerous studies have recently been published on improving upper-limb motor function after stroke. There has been a particular interest in brain stimulation techniques, which could promote brain plasticity. In this review, transcranial Direct Current Stimulation (tDCS) and repetitive Transcranial Magnetic Stimulation ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2012.09.001
更新日期:2012-12-01 00:00:00
abstract:AIM:Evaluate the need for integrated teaching on normal and pathological gait at medical school. METHOD:A questionnaire filled out by 91 French general practitioners (GPs, 130 of whom were contacted) with an average of 19 years of practice and 56 sixth-year medical students. Assessment of the students' knowledge of no...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.11.005
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Insulin resistance is a determining factor in the pathophysiology of type 2 diabetes mellitus (T2DM). Exercise is known to improve insulin resistance, but a systematic review of the literature is lacking. OBJECTIVE:This systematic review and meta-analysis focused on identifying evidence for the effectivenes...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.rehab.2018.11.001
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To evaluate simple, measurable indicators of optimal organizational procedures for the hospital-to-home discharge of dependent patients. MATERIAL AND METHOD:All the general practitioners (GPs) in the Maine-et-Loire county of France were sent a questionnaire asking them to rank the three main criteria (from t...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2011.08.002
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:Analyzing the literature and elaborating recommendations on the following topics: relevance of dorsal root entry zone (DREZ) lesions, surgical treatment for posttraumatic syringomyelia, other therapeutic approaches (peripheral nerve root pain, nerve trunk pain and Sign Posterior Cord [SCI] pain). MATERIAL A...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 共识发展会议,杂志文章
doi:10.1016/j.rehab.2008.12.016
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Patients with back pain can show one or more features of spinal osteoarthritis (OA), such as morning stiffness, limited or painful range of motion (ROM), and lumbar disc degeneration (LDD). However, it has not been investigated whether these features are prognostic of long-term back pain. OBJECTIVES:This st...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2020.07.010
更新日期:2020-08-27 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the prevalence of claw toes and its correlation to other lower limb disorders as well as the global functional recovery in a population of hemiplegic patients 1year post-stroke. PATIENTS AND METHODS:This prospective study included 39 stroke patients hospitalized in the Ph...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2009.12.005
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Physical exercise is widely prescribed in rehabilitation programmes for low back pain (LBP). The LBP patient often asks whether this physical activity should be maintained and, in some cases, whether he/she should resume or take up a sport. PURPOSE:To answer these two questions by performing a review of lit...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2013.08.007
更新日期:2013-10-01 00:00:00
abstract::This document is part of a series of documents designed by the French Physical and Rehabilitation Medicine Society (Sofmer) and the French Federation of PRM (Fedmer). These documents describe the needs for or a specific type of patients; PRM care objectives, human and material resources to be implemented, chronology a...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2011.10.001
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:The Pediatric Stroke Outcome Measure-Summary of Impressions (PSOM-SOI) measures neurological function across right and left sensorimotor domains (Item A), language production (Item B), language comprehension (Item C), and cognition/behaviour (Item D). OBJECTIVE:This study was a cross-cultural adaptation int...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.10.010
更新日期:2019-12-06 00:00:00
abstract:OBJECTIVES:Piriformis Muscle Syndrome (PMS) is caused by sciatic nerve compression in the infrapiriformis canal. However, the pathology is poorly understood and difficult to diagnose. This study aimed to devise a clinical assessment score for PMS diagnosis and to develop a treatment strategy. MATERIAL AND METHODS:Two ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.rehab.2013.04.003
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:Chronic pain is very frequent after spinal cord injury, recent data showing that at least 80% of the patients experience pain, one-third at a severe level. The main objective of the present work is to report and discuss data regarding tools and procedures for the screening, diagnosis, and evaluation of neurop...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.rehab.2008.12.012
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:The role of microRNAs (miRs) in hormone therapy (HT) is of keen interest in developing biomarkers and treatments for individuals with breast cancer. Although miRs are often moderate regulators under homeostatic conditions, their function is changed more in response to physical activity. OBJECTIVE:This singl...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rehab.2019.07.001
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The pronator teres and pronator quadratus muscles are frequently injected with neuromuscular blocking agents to improve supination in children with spastic cerebral palsy and limited active elbow supination. However, determining by simple clinical examination whether these muscles are overactive during activ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.08.001
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Visuospatial neglect (VSN) is a common cognitive disorder after stroke. The primary aim of this systematic review was to provide an overview of the impact of VSN in 3 aspects: (1) activities of daily living (ADL), (2) participation, and (3) caregiver burden. The second aim was to investigate the differences ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2019.05.006
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The management of osteoporosis in spinal cord injury that is a recurring issue in daily practice, but unfortunately, no standard protocol is provided by the literature review, either for screening or for a strategy of prevention and even for therapy. We assessed the practices of the physicians in physical med...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.09.007
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:The main objective of this study was to describe the distribution of referrals offered to patients assessed in the "Post-Acute Stroke program" of Bordeaux University Hospital (France). This program was developed in 2008 to organize the dispensation of care in rehabilitation units specialized in neurological d...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2016.02.003
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:The perception of verticality results from the integration of vestibular, visual and somatosensory information. Spinal cord injured patients with complete paraplegia have total somatosensory deafferentation below a certain metameric segment. In our study, we were interested in the implication of somatosensory s...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.07.005
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:The reliability and validity of a screening test for a deficit in elementary visuo-spatial perception (EVSP) were evaluated. METHOD:This prospective study collected performance from 210 typically developing individuals and evaluated the internal consistency of the EVSP screening test. Test-retest reliability...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.03.006
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Recent studies reported that wearable sensor devices show low validity for assessing the amount of energy expenditure in individuals after stroke. OBJECTIVE:We aimed to evaluate the validity of energy expenditure calculation based on the product of energy cost and walked distance estimated by wearable devic...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.07.002
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:There is little evidence regarding the best way to treat adhesive capsulitis. Physical therapy can reduce pain and improve function and range of motion. However, we lack clear indications on the regimen, techniques or intensity of physical therapy to achieve better results. Intensive physical therapy seems t...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.rehab.2018.07.007
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:To investigate the prevalence of pregnancy-related low back pain (PRLBP) in women in Turkey, identify the factors associated with PRLBP and predict the risk of PRLBP. MATERIALS AND METHODS:This cross-sectional study included a total of 1500 pregnant women admitted to a prenatal care clinic in a secondary ca...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2017.09.005
更新日期:2018-01-01 00:00:00