Abstract:
BACKGROUND:Amyotrophic lateral sclerosis (ALS) has long been considered a pure motor neurodegenerative disease. However, now, extra-motor manifestations such as cognitive-behavioral disorders are considered not rare and are even a severity factor of the disease. Experiencing anosognosia (i.e., the inability to recognize neurological symptoms) might affect care and treatment compliance in ALS. Regardless, this pivotal feature has been little investigated. OBJECTIVES:By comparing patients' and caregivers' reports, we analysed whether patients with ALS would experience a lack of awareness about their executive disorders and their apathy symptoms. METHODS:From the ALS reference center in Paris, we included 85 patients (47 men, mean [SD] age 60.5 [12] years and ALS-Functional Rating Scale-revised score 8 to 46) and their primary family caregivers who all completed the Dysexecutive Questionnaire (DEX) and the Apathy Evaluation Scale (AES). Overall scores and answers were compared by agreement/disagreement statistical methods. RESULTS:Caregivers reported higher levels of cognitive-behavioral disorders than did patients, but reports matched when cognitive-behavioral disorders were absent or mild. With published DEX and AES cutoffs, 32% and 51% of patients had executive disorders and apathy, respectively. In these patients with significant impairment, Bland-Altman plots (i.e., visual display agreement that represents the difference between the patient's and caregiver's scores as a function of their average) showed a strong discrepancy between joint reports: patients underestimated their symptoms by a mean bias of -6.81 DEX points (95% confidence interval -11.88, -1.75) and -8.85 AES points (95% confidence interval -11.72, -5.98). We found no clear relationship between bulbar or spinal ALS subtypes and anosognosia. CONCLUSIONS:ALS patients with a cognitive-behavioral phenotype show anosognosia by a mismatch between self and proxy reports, which warrants further investigation in neuroimaging. Systematic longitudinal screening of anosognosia is needed to propose targeted psychoeducation in patient-caregiver dyads showing disagreement.
journal_name
Ann Phys Rehabil Medjournal_title
Annals of physical and rehabilitation medicineauthors
Salah AB,Pradat PF,Villain M,Balcerac A,Pradat-Diehl P,Salachas F,Lacomblez L,Bayen Edoi
10.1016/j.rehab.2020.08.004subject
Has Abstractpub_date
2020-10-13 00:00:00eissn
1877-0657issn
1877-0665pii
S1877-0657(20)30171-8pub_type
杂志文章abstract:BACKGROUND:Constraint-induced movement therapy (CIMT) is increasingly recognized as an effective therapy for children with hemiparesis. However, the effectiveness of CIMT outside the standard rehabilitation protocol in clinical settings is less known. The aim of this systematic review was to investigate the effectivene...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2017.10.004
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:For hospitalizations in rehabilitation centers (RCs) in France, the quantification of healthcare givers' activity is based on the dependency of the patients, defined as a total or partial inability to perform activities required for daily living without help. The tools currently used to quantify dependency a...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2018.04.006
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Blocking the lumbar or lumbosacral spine with a custom-made rigid lumbar brace, based on the mechanical origin of active discopathy, is a therapeutic option for low back pain, but no study has yet defined its applicability in low back pain. OBJECTIVE:To assess the pain evolution of individuals with non-spec...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2018.06.008
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Compare the clinical outcomes of different knee braces in the early phase of rehabilitation after anterior cruciate ligament reconstruction (ACLR) in athletes. MATERIALS AND METHODS:We conducted a retrospective database study of athletes during early rehabilitation in a tertiary referral hospital between 1 F...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2017.02.001
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:Previous research suggested isolated associations of physical and psychological factors with fibromyalgia severity. Integration of physical and psychological, experienced and observed, modifiable factors associated with fibromyalgia severity in a single model will reveal therapeutic paths toward less severit...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.06.017
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To present an up-to-date literature review of osteoporosis in spinal cord injury (SCI) patients, in view of the seriousness of this complication (with a high risk of fractures) and the complexity of its diagnosis, evaluation and treatment. METHODS:A Medline search with the following keywords: immobilization ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2010.10.001
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:In a survey of 100 transtibial amputees (TTA) in the study place, it was noticed that nearly 30% of total activities performed by crutches. It was recorded nearly 52% of the amputees were totally independent, 39% had to use a crutch or cane and only 9% need not used any devices simply because they are unawar...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2012.02.006
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:The Leisure Time Physical Activity Questionnaire (LTPAQ) measures the duration of physical activities performed during the past 7 days, and results are expressed in minutes. This study aimed to translate this questionnaire into Canadian-French and to evaluate the content validity and its test-retest reliabil...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2018.12.002
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The pronator teres and pronator quadratus muscles are frequently injected with neuromuscular blocking agents to improve supination in children with spastic cerebral palsy and limited active elbow supination. However, determining by simple clinical examination whether these muscles are overactive during activ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.08.001
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:The Osteoarthritis Quality of Life scale (OAQoL) is an osteoarthritis-specific measure developed in the United Kingdom by a needs-based approach. This study describes the adaptation and validation of this English scale into French. METHODS:The OAQoL was translated into French by a dual-panel technique follow...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2015.09.003
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the effect of running retraining on the recovery of the knee's functional and muscular properties after anterior cruciate ligament (ACL) reconstruction. METHODS:Eighty-five athletes who had undergone ACL reconstruction surgery were selected randomly to receive, or not to ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rehab.2009.12.006
更新日期:2010-04-01 00:00:00
abstract:AIM:Evaluate the need for integrated teaching on normal and pathological gait at medical school. METHOD:A questionnaire filled out by 91 French general practitioners (GPs, 130 of whom were contacted) with an average of 19 years of practice and 56 sixth-year medical students. Assessment of the students' knowledge of no...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.11.005
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the prevalence of claw toes and its correlation to other lower limb disorders as well as the global functional recovery in a population of hemiplegic patients 1year post-stroke. PATIENTS AND METHODS:This prospective study included 39 stroke patients hospitalized in the Ph...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2009.12.005
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:The Pediatric Stroke Outcome Measure-Summary of Impressions (PSOM-SOI) measures neurological function across right and left sensorimotor domains (Item A), language production (Item B), language comprehension (Item C), and cognition/behaviour (Item D). OBJECTIVE:This study was a cross-cultural adaptation int...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2019.10.010
更新日期:2019-12-06 00:00:00
abstract:OBJECTIVE:Chronic pain is very frequent after spinal cord injury, recent data showing that at least 80% of the patients experience pain, one-third at a severe level. The main objective of the present work is to report and discuss data regarding tools and procedures for the screening, diagnosis, and evaluation of neurop...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.rehab.2008.12.012
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:There are no handbook or recommendations for the use of pharmacological agents to treat neurobehavioral disorders after traumatic brain injury (TBI). This work proposes a systematic review of the literature and a user guide on neuroleptics, antidepressants, beta-blockers, mood stabilizers and other medication...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,实务指引,评审
doi:10.1016/j.rehab.2015.10.003
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Flap surgery for deep pelvic pressure ulcers (PPUs) has been found effective, but the recurrence rate remains high and few risk factors have been identified. OBJECTIVE:We evaluated risk factors for PU recurrence after primary flap surgery in people with spinal cord injury (SCI). PATIENTS AND METHODS:This o...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2018.08.005
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The management of osteoporosis in spinal cord injury that is a recurring issue in daily practice, but unfortunately, no standard protocol is provided by the literature review, either for screening or for a strategy of prevention and even for therapy. We assessed the practices of the physicians in physical med...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.09.007
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Upper-limb robotic-assisted therapy (RAT) is promising for stroke rehabilitation, particularly in the early phase. When RAT is provided as partial substitution of conventional therapy, it is expected to be at least as effective or might be more effective than conventional therapy. Assessments have usually be...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.rehab.2019.04.002
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To assess with an isokinetic dynamometer the force and endurance of the spinal flexor and extensor muscles in pre-teens or teens aged 11 to 13 and 14 to 16 years with and without low back pain (LBP). METHOD:The control group and the LBP group were homogeneous in terms of age, weight, height and Body Mass Ind...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2013.10.004
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:The pre-return-to-work medical consultation during sick leave for low back pain (LBP) aims at assessing the worker's ability to resume working without risk for his/her health, and anticipating any difficulties inherent to returning to work and job retention. This article summarizes the good practices guideli...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rehab.2015.08.001
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:There is little evidence regarding the best way to treat adhesive capsulitis. Physical therapy can reduce pain and improve function and range of motion. However, we lack clear indications on the regimen, techniques or intensity of physical therapy to achieve better results. Intensive physical therapy seems t...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.rehab.2018.07.007
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The role of microRNAs (miRs) in hormone therapy (HT) is of keen interest in developing biomarkers and treatments for individuals with breast cancer. Although miRs are often moderate regulators under homeostatic conditions, their function is changed more in response to physical activity. OBJECTIVE:This singl...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rehab.2019.07.001
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Botuloscope is a cohort study supported by a French public grant and aiming to evaluate a 1-year treatment of the post-stroke spastic upper limb with botulinum toxin type A (BoNT-A) in terms of individual satisfaction with respect to personalized goals and quality of life. METHODS:This was an open-label pro...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.rehab.2019.06.003
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:The main objective of this study was to describe the distribution of referrals offered to patients assessed in the "Post-Acute Stroke program" of Bordeaux University Hospital (France). This program was developed in 2008 to organize the dispensation of care in rehabilitation units specialized in neurological d...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2016.02.003
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To evaluate simple, measurable indicators of optimal organizational procedures for the hospital-to-home discharge of dependent patients. MATERIAL AND METHOD:All the general practitioners (GPs) in the Maine-et-Loire county of France were sent a questionnaire asking them to rank the three main criteria (from t...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2011.08.002
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION:Sociocultural factors may influence the impact of chronic low back pain (cLBP) on patients. The goal of this study was to compare pain and disability levels, and psychobehavioural parameters in four French-speaking countries in patients with cLBP. METHODS:Two hundred and seventy-eight patients were includ...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2009.08.002
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:To specify outcomes and identify prognostic factors of neurologic and functional recovery in patients with an acute traumatic spinal cord injury (SCI) associated with cervical spinal canal stenosis (SCS), without spinal instability. METHODS:A retrospective study was conducted using data from a Regional Depa...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2017.09.003
更新日期:2018-01-01 00:00:00
abstract::This document is part of the "Care Pathways in Physical and Rehabilitation Medicine" series developed by the French Physical and Rehabilitation Medicine Society (Sofmer) and the French Physical and Rehabilitation Medicine Federation (Fedmer). For a given patient profile, each concise document describes the patient's n...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2012.08.010
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:The perception of verticality results from the integration of vestibular, visual and somatosensory information. Spinal cord injured patients with complete paraplegia have total somatosensory deafferentation below a certain metameric segment. In our study, we were interested in the implication of somatosensory s...
journal_title:Annals of physical and rehabilitation medicine
pub_type: 杂志文章
doi:10.1016/j.rehab.2010.07.005
更新日期:2010-11-01 00:00:00