Abstract:
:A number of systemic medications are known to cause macular toxicity, and bull's eye maculopathy is caused by some of them like hydroxychloroquine and clofazimine. A 55-year-old female, known case of vitiligo with history of undergoing methoxsalen-ultraviolet A therapy, presented with painless defective vision in both eyes. Fundus examination and autofluorescence showed macular degeneration with bull's eye configuration. Optical coherence tomography showed perifoveal loss of photoreceptors and outer retinal thinning with foveal sparing appearing as 'flying saucer'. Multifocal electroretinogram showed pan-macular suppression of waveforms. Patient was diagnosed as case of methoxsalen-induced advanced macular toxicity. This is the first reported case of methoxsalen-induced advanced bull's eye maculopathy.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Ranjan R,Manayath GJ,Salian R,Narendran Vdoi
10.1177/1120672120907317subject
Has Abstractpub_date
2020-02-16 00:00:00pages
1120672120907317eissn
1120-6721issn
1724-6016pub_type
杂志文章abstract:PURPOSE:To compare lateral rectus recession (LRc) and medial rectus advancement (MRadv) for correction of consecutive exotropia (CXT). METHODS:Of the 43 exotropic patients 20 of them underwent LRc (group 1) and 23 of them underwent MRadv (group 2). Postoperative exodrift, strabismic angle, dose effect relationship wer...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120983199
更新日期:2021-01-09 00:00:00
abstract:PURPOSE:To describe a case of multiorganism, drug-resistant keratitis that responded well to corneal crosslinking (CXL) treatment. METHODS:A 52-year-old man presented to our institute with a 2-month ocular history of infectious keratitis in his right eye, on topical antibacterial, antifungal, and antiprotozoan treatme...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000755
更新日期:2016-07-01 00:00:00
abstract::Abstracts from the 25th Meeting of the European Association for the Study of Diabetes Eye Complications Study Group (EASDec). Turin, Italy - June 26-28, 2015. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000612
更新日期:2015-04-22 00:00:00
abstract:PURPOSE:Vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) are angiogenic mediators that share a significant proinflammatory activity. Both substances have been suggested to play a key role in uveitis pathogenesis. The authors analyzed VEGF and IL-8 levels in the aqueous humor and serum of patients with...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700611
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:To assess the long-term anatomical and functional results of balloon buckle surgery for rhegmatogenous retinal detachment. PATIENTS AND METHODS:Twenty-five selected detachments with a single break or a group of breaks close together were treated with a temporary parabulbar balloon. Adhesion was obtained with t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100410
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:The aim of this study is to assess the agreement between manual and automated gonioscopy for iridocorneal angle opening. METHODS:The research is a cross-sectional observational study. Manual and automated gonioscopy were performed to consecutive patients in a glaucoma clinic. Iridocorneal angle opening grading...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118806436
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To compare the efficacy of selective laser trabeculoplasty (SLT) to argon laser trabeculoplasty (ALT) as treatment and retreatment to lower intraocular pressure (IOP) in patients with uncontrolled open-angle glaucoma (OAG) on maximally tolerated medication therapy with a follow-up of 12 months. METHODS:A total...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210901900317
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Handheld laser pointer thermal injury affects primarily the retinal pigment epithelium (RPE). However, so far no study has reported on the possible effects of laser pointers in the deeper layers, beneath the RPE. Here, we describe the spectral-domain optical coherence tomography angiography findings in the chor...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000844
更新日期:2017-01-19 00:00:00
abstract:PURPOSE:The present study compared the expression of brain-derived neurotrophic factor (BDNF) in the lateral geniculate body between form deprivation amblyopia kittens and normal kittens to examine the significance of BDNF in the lateral geniculate body in the pathogenesis of amblyopia. METHODS:Twenty kittens were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120953341
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate diabetic retinopathy (DR) prevalence and risk factors, and the effectiveness of nonmydriatic fundus camera as a screening tool for the detection of DR, in a safety net hospital. METHODS:This was a retrospective, population-based, cross-sectional study. Diabetic patients, referred by their primary c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000515
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. MATERIALS AND METHODS:A case-control ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119850071
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). METHODS:Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of pr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000234
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG). METHODS:We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000762
更新日期:2016-11-04 00:00:00
abstract:PURPOSE:To evaluate the effect of posterior sub-tenon triamcinolone acetonide (TA) injection on clinical, angiographic, and optical coherence tomographic (OCT) parameters in refractory diabetic macular edema (DME). METHODS:In a double-masked placebo-controlled clinical trial, 64 eyes were randomly assigned to two grou...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210501500614
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To assess incidence and risk factors of cataract extraction in patients with primary congenital glaucoma, surgical outcome, and complications. MATERIAL AND METHOD:Retrospective cohort study, in which 108 patients with primary congenital glaucoma were included. Data collected were need for cataract extraction...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119841190
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000851
更新日期:2017-05-11 00:00:00
abstract:PURPOSE:Avastin (bevacizumab) intravitreal injections are widely used for treatment of diabetic retinopathy. The aim of our study was to analyze effect of 1.25 mg of intravitreal Avastin on serum concentration of vascular endothelial growth factor (VEGF) in diabetic patients. METHODS:Participants were 10 diabetic pati...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000118
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:Evaluate the long term outcomes of myopic-LASIK in a late adolescent population (age ⩾17 and <20 at the time of surgery). METHODS:Monocentric retrospective case series study. Eyes with at least 3 years of follow-up time were included. Primary outcome measures were long term efficacy, safety and stability of th...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969039
更新日期:2020-10-30 00:00:00
abstract:PURPOSE:To describe a technique for suturing a luxated intraocular lens (IOL) in the vitreous cavity directly to the ciliary sulcus using intraocular slipknot without IOL extraction. DESIGN:Noncomparative interventional case series. MATERIALS AND METHODS:A three-port vitrectomy was performed in all cases. According t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300604
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To report a case of posterior microphthalomos (PM) related to PRSS56 gene mutation with long term follow up with multimodal imaging findings. METHODS:Single retrospective case report. RESULTS:A 43-year old male patient presented in 2009 with bilateral reduced vision. Clinical examination and multimodal imagin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120949756
更新日期:2020-08-17 00:00:00
abstract:PURPOSE:To report the results of corneal collagen crosslinking (CXL) in a patient with corneal ectasia developed after excimer laser-assisted lamellar keratoplasty for keratoconus and a secondary photorefractive keratectomy (PRK) for residual refractive error. METHODS:A 33-year-old woman, who had originally been treat...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000019
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To assess eye movements pattern during reading process in patients with primary open-angle glaucoma (POAG) using a microperimeter. METHODS:Thirty-two patients with POAG at early and moderate stage, according to Glaucoma Staging System 2, and 34 healthy age- and sex-matched subjects were included in the study. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000397
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of needle revision and examine factors predictive of failure. METHODS:In total, 157 eyes of 131 patients that underwent needle revision augmented with either 5-fluorouracil or betamethasone for trabeculectomy failure were included in this retrospective study. Complete failur...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119830861
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To determine agreement between peripapillary retinal nerve fiber layer (RNFL) thickness measurements by 2 spectral domain optical coherence tomography (SD-OCT) instruments. METHODS:. This was an observational, cross-sectional study. Both eyes of 89 subjects, 44 healthy subjects (mean age, 47±15 years) and 45 ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000167
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To describe the neuro-ophthalmic manifestations of patients with intracranial cavernous hemangiomas (cavernomas). METHODS:A retrospective review of all patients with intracranial cavernomas with neuroophthalmic manifestations who were treated at the Royal Adelaide Hospital in Australia between 1994 and 2004. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600124
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To evaluate the long-term results of pars plana vitrectomy (PPV) and silicone oil implantation (SOI) for giant retinal tears (GT). METHODS:PPV with SOI was performed for GT in 50 eyes of 46 patients. Thirty-one eyes (62%) of 27 patients suffered from idiopathic GT. A direct injury of the eye preceded GT in 19 ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND/AIMS:To assess structural and functional outcomes of treatment with intravitreal aflibercept (®Eylea) for diabetic macular oedema in treatment-naïve patients. METHODS:Sixty-four eyes receiving intravitreal anti-vascular endothelial growth factor therapy were included in the data analysis of this retrospecti...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120925034
更新日期:2020-05-19 00:00:00
abstract:PURPOSE:To establish the real localization of rifabutin-related corneal deposits in a patient with human immunodeficiency virus (HIV) infection by in vivo HRT II confocal microscopy with related clinicopathologic implications. METHODS:Observational case report. After Siena University Institutional Review Board approva...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900327
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To report the visual and refractive outcomes of sequential intracorneal ring segment (ICRS) and toric phakic intraocular lens (IOL) insertion for visual rehabilitation in keratoconus. METHODS:A retrospective interventional cohort study was performed through the Corneoplastics unit and Eye Bank, Queen Victoria ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969600
更新日期:2020-11-02 00:00:00
abstract:AIM:A multicentre, randomized, placebo-controlled double-masked study was conducted to assess the efficacy and safety of Rimexolone 1% eye drops in reducing inflammation after cataract surgery and intra-ocular lens implantation. METHODS:Rimexolone 1% (124 patients) or placebo (58 patients) was given, four times a day ...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1998-01-01 00:00:00