Measurement of cortical microcirculation during intracranial aneurysm surgery by combined laser-Doppler flowmetry and photospectrometry.

Abstract:

BACKGROUND:Accidental vessel occlusion is one major risk of intracranial aneurysm surgery potentially causing cerebral ischemia. The intraoperative assessment of cerebral ischemia remains a technological challenge. OBJECTIVE:As a novel approach, cortical tissue integrity was monitored using simultaneous measurements of regional capillary-venous cerebral blood flow (rvCBF), oxygen saturation (Srvo2), and hemoglobin amount (rvHb) during aneurysm surgery. METHODS:Fifteen patients scheduled for aneurysm surgery of the anterior and posterior circulation were included. A fiber optic probe was placed on the cortex associated with the distal branch of the aneurysmatic vessel. Blinded measurements by combined laser-Doppler flowmetry (rvCBF) and photospectrometry (Srvo2, rvHb) were performed before and after surgical clipping or trapping of the aneurysm. Data were correlated with postoperative imaging and neurological outcome. RESULTS:Cortical measurements could be successfully performed in all patients. Significant increase (>25% change from baseline) or decrease (<25% change from baseline) of rvCBF, Srvo2, and rvHb was detectable in 33 to 46% of patients after surgical intervention. Severe decrease (>50% change from baseline) of all parameters or solitary of rvCBF was correlated to reduced cerebral perfusion and neurological deficits in 2 patients. CONCLUSION:Combined laser-Doppler flowmetry and photospectrometry provides real-time information on cortical microcirculation. Intraoperative alterations of parameters (rvCBF, Srvo2, rvHb) might reflect changes of cerebral tissue integrity during intracranial aneurysm surgery.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Klein KU,Stadie A,Fukui K,Schramm P,Werner C,Oertel J,Engelhard K,Fischer G

doi

10.1227/NEU.0b013e3182178bc9

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

391-8

issue

2

eissn

0148-396X

issn

1524-4040

journal_volume

69

pub_type

杂志文章
  • Intracranial meningiomas in the aged: surgical outcome in the era of computed tomography.

    abstract::Seventy-five patients older than 60 years of age underwent surgical resection of intracranial meningiomas during a 10-year period at a single institution. All patients had a computed tomographic scan preoperatively, and all were followed for at least 3 months postoperatively. There were 50 patients 61 to 70 years of a...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198904000-00011

    authors: Awad IA,Kalfas I,Hahn JF,Little JR

    更新日期:1989-04-01 00:00:00

  • Intraparenchymal and intratumoral interstitial infusion of anti-glioma monoclonal antibody 8H9.

    abstract:OBJECTIVE:Interstitial infusion, a form of local delivery that bypasses the blood-brain barrier, has been shown to afford high regional concentrations of a therapeutic molecule while avoiding systemic exposure. The distribution of monoclonal antibodies administered via interstitial infusion has not been characterized, ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000334052.60634.84

    authors: Luther N,Cheung NK,Dunkel IJ,Fraser JF,Edgar MA,Gutin PH,Souweidane MM

    更新日期:2008-12-01 00:00:00

  • Cerebral autoregulation among patients with symptoms of hydrocephalus.

    abstract:OBJECTIVE:To study the relationship between the resistance to cerebrospinal fluid (CSF) outflow and cerebral autoregulation. METHODS:We examined 35 patients who presented with ventricular dilation and clinical symptoms of communicating hydrocephalus. For all of these patients, CSF compensatory reserve was investigated...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200203000-00018

    authors: Czosnyka ZH,Czosnyka M,Whitfield PC,Donovan T,Pickard JD

    更新日期:2002-03-01 00:00:00

  • Cancer after spinal fusion: the role of bone morphogenetic protein.

    abstract:BACKGROUND:Bone morphogenetic protein (BMP) is used in tens of thousands of spinal fusions each year. A trial evaluating a high-dose BMP formulation demonstrated that its use may be associated with an increased risk of cancer. OBJECTIVE:To evaluate whether BMP, as commonly used today, is associated with an increased r...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000000018

    authors: Lad SP,Bagley JH,Karikari IO,Babu R,Ugiliweneza B,Kong M,Isaacs RE,Bagley CA,Gottfried ON,Patil CG,Boakye M

    更新日期:2013-09-01 00:00:00

  • Moyamoya disease presenting as intracerebral hemorrhage during pregnancy: case report and review of the literature.

    abstract::Intracranial hemorrhage during pregnancy is rare. The authors present a case of moyamoya disease associated with pregnancy. A 32-year-old woman who was at 32 weeks of gestation experienced sudden severe headache followed by loss of consciousness. Computed tomography revealed an intracerebral hematoma in the left tempo...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198701000-00009

    authors: Enomoto H,Goto H

    更新日期:1987-01-01 00:00:00

  • Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells.

    abstract::To investigate the role of protein kinase C (PKC) in the growth of astrocytic brain tumors, human glioblastoma cell line U-87 was stably transfected with the antisense complementary deoxyribonucleic acid encoding PKC alpha. The effect of selectively down-regulating the alpha isoform on other PKC isoforms, as well as s...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199411000-00015

    authors: Ahmad S,Mineta T,Martuza RL,Glazer RI

    更新日期:1994-11-01 00:00:00

  • Combined pretemporal and endovascular approach to the cavernous sinus for the treatment of carotid-cavernous dural fistulae: technical case report.

    abstract:OBJECTIVE AND IMPORTANCE:The endovascular treatment of carotid-cavernous dural fistulae is becoming the prominent treatment modality for these lesions. The intractability of these lesions and their tendency to recur, especially after previous endovascular treatment sessions, exhausts the available routes and tends to p...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199902000-00113

    authors: Krisht AF,Burson T

    更新日期:1999-02-01 00:00:00

  • Paramedian supracerebellar transtentorial approach for a medial tentorial meningioma with supratentorial extension: technical case report.

    abstract:OBJECTIVE AND IMPORTANCE:The choice of surgical approach to treat medial tentorial meningiomas is crucial and sometimes difficult to make. Although the subtemporal approach is most commonly used for lesions that extend mostly supratentorially, it risks injury to the vein of Labbé or the veins coursing along the subtemp...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200112000-00036

    authors: Uchiyama N,Hasegawa M,Kita D,Yamashita J

    更新日期:2001-12-01 00:00:00

  • Electrophysiological aid in high thoracic sympathectomy for palmar hyperhidrosis.

    abstract::High upper thoracic sympathectomy using microsurgical techniques aided by electrical stimulation of the sympathetic chain is described. Use of the microscope facilitates identification and dissection of the sympathetic chain and minimizes the risk of pleural damage. Electrical stimulation of the sympathetic chain esta...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198903000-00026

    authors: Lindquist C,Fedorcsak I,Steig PE

    更新日期:1989-03-01 00:00:00

  • Hemangioblastoma of the radial nerve: case report.

    abstract::A case of hemangioblastoma of the right radial nerve is presented. Hemangioblastomas are rare vascular neoplasms characteristically associated with the Von Hippel-Lindau syndrome, in which they are found in the retina, the posterior fossa, and, less often, the spinal cord. Thought of as primary central nervous system ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199501000-00028

    authors: Brodkey JA,Buchignani JA,O'Brien TF

    更新日期:1995-01-01 00:00:00

  • Rehabilitative neurosurgery.

    abstract::The neurosurgical role in rehabilitation rehabilitation was studied. Over a 5-year period, 850 individuals were referred to a rehabilitation center after initial acute care. Surgery was indicated for 66 patients. There were 28 quadriplegic or paraplegic individuals with intractable spasticity. Percutaneous radiofreque...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198603000-00009

    authors: Herz DA,Gregerson M,Pearl L

    更新日期:1986-03-01 00:00:00

  • Clinical use of the optical digitizer for intracranial neuronavigation.

    abstract:OBJECTIVE:Computer-assisted frameless navigation techniques are used in many centers for intracranial neurosurgical procedures. In this study, we assessed the accuracy and the clinical usefulness of a frameless system based on the optical digitizer in a variety of intracranial procedures. METHODS:The optical digitizer...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199908000-00013

    authors: Germano IM,Villalobos H,Silvers A,Post KD

    更新日期:1999-08-01 00:00:00

  • Meningiomas of the internal auditory canal.

    abstract:OBJECTIVE:Meningiomas arising primarily within the internal auditory canal (IAC) are notably rare. By far the most common tumors that are encountered in this region are neuromas. We report a series of eight patients with meningiomas of the IAC, analyzing the clinical presentations, surgical management strategies, and c...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/01.neu.0000126887.55995.e7

    authors: Nakamura M,Roser F,Mirzai S,Matthies C,Vorkapic P,Samii M

    更新日期:2004-07-01 00:00:00

  • Sequentially staged resection and 2-column reconstruction for C2 tumors through a combined anterior retropharyngeal-posterior approach: surgical technique and results in 11 patients.

    abstract:BACKGROUND:Surgical treatment of C2 tumors remains challenging. Because of the deep location and unique anatomical complexity, anterior exposure in this region is considered difficult and dangerous, and few reports concerning anterior tumor resection and reconstruction exist. OBJECTIVE:To describe a technique of seque...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31821bc7f9

    authors: Yang X,Wu Z,Xiao J,Teng H,Feng D,Huang W,Chen H,Wang X,Yuan W,Jia L

    更新日期:2011-12-01 00:00:00

  • Neonatal ventriculosubgaleal shunts.

    abstract:OBJECTIVE:We report on 32 neonates treated with ventriculosubgaleal (VSG) shunts to determine VSG shunt survival and associated complications. METHODS:Between 1993 and 1997, 37 VSG shunts were placed in 32 neonates when the cerebrospinal fluid (CSF) or the abdomen was considered unsuitable for ventriculoperitoneal shu...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200007000-00018

    authors: Fulmer BB,Grabb PA,Oakes WJ,Mapstone TB

    更新日期:2000-07-01 00:00:00

  • 116 years (1889-2005) of neurosurgical practice and education at Gulhane Military Medical Academy.

    abstract::Modern medical education in the Ottoman Empire began with the founding of the School of Medicine and Surgery in 1827. This was a military school established to provide military physicians for the army. The first neurosurgical interventions at this school were initiated by Cemil Pasha in 1889. This school has gradually...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1227/01.NEU.0000197488.65065.C3

    authors: Timurkaynak E,Izci Y,Acar F

    更新日期:2006-03-01 00:00:00

  • A new ventriculoperitoneal shunt with a telemetric intracranial pressure sensor: clinical experience in 94 patients with hydrocephalus.

    abstract:OBJECTIVE:We have developed a telemetric intracranial pressure sensor (OSAKA telesensor; Nagano Keiki Seisakusyo Co. Ltd., Tokyo, Japan) and investigated the clinical usefulness of new ventriculoperitoneal shunting with an OSAKA telesensor, an on-off valve, and a programmable valve. METHODS:The OSAKA telesensor was ap...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199705000-00009

    authors: Miyake H,Ohta T,Kajimoto Y,Matsukawa M

    更新日期:1997-05-01 00:00:00

  • Angioscopy-assisted aneurysm clipping.

    abstract:OBJECTIVE:To test the concept that endovascular angioscopy can assist surgical intracranial aneurysm clipping by providing an endoluminal view of the aneurysm-parent vessel complex. METHODS:A carotid bifurcation aneurysm was surgically created in a dog at the lingual artery origin. A balloon catheter was inflated prox...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199909000-00032

    authors: Lanzino G,Miskolczi L,Guterman LR,Hopkins LN

    更新日期:1999-09-01 00:00:00

  • Subependymoma of the cervical spinal cord.

    abstract::A case of subependymoma of the spinal cord in the cervical region is presented. Our experience with this patient and the seven cases of spinal cord subependymoma previously reported show that this tumor predominates in the cervical region and in males (3:1). Although radical removal is considered the rational goal of ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198904000-00024

    authors: Vaquero J,Martinez R,Vegazo I,Pontón P

    更新日期:1989-04-01 00:00:00

  • Comparison of three methods of targeting the subthalamic nucleus for chronic stimulation in Parkinson's disease.

    abstract:OBJECTIVE:The success of subthalamic nucleus (STN) surgery for Parkinson's disease depends on accuracy in target determination. The objective of this study was to determine which of the following techniques was most accurate and precise in identifying the location for stimulation in STN deep brain stimulation surgery t...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000316289.75736.55

    authors: Andrade-Souza YM,Schwalb JM,Hamani C,Eltahawy H,Hoque T,Saint-Cyr J,Lozano AM

    更新日期:2008-02-01 00:00:00

  • Lumbar Surgery in the Elderly Provides Significant Health Benefit in the US Health Care System: Patient-Reported Outcomes in 4370 Patients From the N2QOD Registry.

    abstract:BACKGROUND:Lumbar spine degenerative pathologies are prevalent in the United States. The health benefit of spine surgery in the elderly has been questioned. OBJECTIVE:To compare effectiveness, morbidity, and quality of care associated with surgical management of degenerative lumbar spinal disorders in elderly vs nonel...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000000952

    authors: McGirt MJ,Parker SL,Hilibrand A,Mummaneni P,Glassman SD,Devin CJ,Asher AL

    更新日期:2015-10-01 00:00:00

  • Mini-open stabilization of a sacral fracture: technical case report.

    abstract:BACKGROUND AND IMPORTANCE:Comminuted sacral fractures present significant challenges for operative management. Open and percutaneous sacroiliac screws have been used for stabilization but carry not insignificant rates of complications, including wound infection for the former and malposition and neurological injury for...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31826cdfd7

    authors: Hong J,Spire WJ,Simmons NE

    更新日期:2013-03-01 00:00:00

  • Hydrosyringomyelia and its management in childhood.

    abstract::Syringomyelia, once regarded as a degenerative disease of adults, is now recognized to be a disorder usually associated with the Chiari malformation and occurring in patients of all ages. We have reviewed 47 patients with syringomyelia treated on the Neurosurgical Service at the Hospital for Sick Children during the y...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198709000-00012

    authors: Hoffman HJ,Neill J,Crone KR,Hendrick EB,Humphreys RP

    更新日期:1987-09-01 00:00:00

  • Elevation of brain norepinephrine concentration after experimental subarachnoid hemorrhage.

    abstract::Regional brain tissue catecholamine concentrations were measured in 5 control rats and in 10 rats 72 hours after experimental subarachnoid hemorrhage (SAH). Catecholamine levels were determined in the cerebral hemispheres, brain stem, and cerebellum of each animal using a radioenzymatic assay. Three days after SAH, th...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198609000-00005

    authors: Solomon RA,McCormack BM,Lovitz RN,Swift DM,Hegemann MT

    更新日期:1986-09-01 00:00:00

  • Nonvestibular schwannomas of the brain: a 7-year experience.

    abstract:OBJECTIVE:Nonvestibular schwannomas are uncommon tumors of the brain. Trigeminal nerve schwannomas are the most common of this group, followed by glossopharyngeal, vagal, facial, accessory, hypoglossal, oculomotor, trochlear, and abducens nerve schwannomas, in descending order of frequency. We present a series of nonve...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200203000-00002

    authors: Sarma S,Sekhar LN,Schessel DA

    更新日期:2002-03-01 00:00:00

  • Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review.

    abstract:BACKGROUND:Primary leptomeningeal gliomatosis (PLG) is a poorly recognized tumor of the central nervous system. OBJECTIVE:To describe the histopathological, immunohistochemical, and molecular features of PLG. METHODS:Results of our multicentric retrospective study of 6 PLG cases (3 pediatric and 3 adult) were compare...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.1227/NEU.0000000000001028

    authors: Tauziede-Espariat A,Maues de Paula A,Pages M,Laquerriere A,Caietta E,Delpont B,Viennet G,Medeiros de Bustos E,Moulin T,Barnerias C,Vauleon E,Grill J,Chiforeanu D,Vasiljevic A,Varlet P

    更新日期:2016-03-01 00:00:00

  • Symptomatic Adjacent Level Disease Requiring Surgery: Analysis of 10-Year Results From a Prospective, Randomized, Clinical Trial Comparing Cervical Disc Arthroplasty to Anterior Cervical Fusion.

    abstract:BACKGROUND:Ten-year follow-up data from the US Food and Drug Administration investigational device exemption trial comparing BRYAN® Cervical Disc (Medtronic, Dublin, Ireland) arthroplasty to anterior cervical discectomy and fusion (ACDF) demonstrated that disc arthroplasty maintained range of motion and improvements in...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/neuros/nyy118

    authors: Ghobrial GM,Lavelle WF,Florman JE,Riew KD,Levi AD

    更新日期:2019-02-01 00:00:00

  • Continuous assessment of the cerebral vasomotor reactivity in head injury.

    abstract:OBJECTIVE:Cerebrovascular vasomotor reactivity reflects changes in smooth muscle tone in the arterial wall in response to changes in transmural pressure or the concentration of carbon dioxide in blood. We investigated whether slow waves in arterial blood pressure (ABP) and intracranial pressure (ICP) may be used to der...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199707000-00005

    authors: Czosnyka M,Smielewski P,Kirkpatrick P,Laing RJ,Menon D,Pickard JD

    更新日期:1997-07-01 00:00:00

  • Involvement of the external carotid arteries in moyamoya disease: neuroradiological evaluation of 66 patients.

    abstract::Arterial stenoses and/or occlusions in moyamoya disease are mainly localized intracranially, although some instances of stenotic lesions of the extracranial arteries have been reported in some autopsy cases. We have reviewed the angiograms of 66 patients with moyamoya disease to investigate whether stenotic lesions ar...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199209000-00002

    authors: Hoshimaru M,Kikuchi H

    更新日期:1992-09-01 00:00:00

  • Cerebral Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Comparison of Management Approaches.

    abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a risk factor for formation of intracranial aneurysms (IAs), though the ideal screening and treatment strategies in this population are unclear. OBJECTIVE:To report outcomes of observation, open surgical, or endovascular management of ruptured and unru...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyy336

    authors: Wilkinson DA,Heung M,Deol A,Chaudhary N,Gemmete JJ,Thompson BG,Pandey AS

    更新日期:2019-06-01 00:00:00