Abstract:
BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a risk factor for formation of intracranial aneurysms (IAs), though the ideal screening and treatment strategies in this population are unclear. OBJECTIVE:To report outcomes of observation, open surgical, or endovascular management of ruptured and unruptured aneurysms in patients with ADPKD. METHODS:We performed a retrospective analysis of all patients with ADPKD and IAs at a single center from 2000 to 2016. RESULTS:Forty-five patients with ADPKD harboring 71 aneurysms were identified, including 11 patients with subarachnoid hemorrhage (SAH). Of 22 aneurysms managed with observation, none ruptured in 136 yr of clinical follow-up. Thirty-five aneurysms were treated with open surgery and 14 with an endovascular approach. Among treated aneurysms, poor neurologic outcome (modified Rankin scale >2) was seen only in patients presenting with SAH (17% SAH vs 0% elective, P = .06). Acute kidney injury (AKI) was also significantly associated with SAH presentation (22% SAH vs 0% elective, P = .05). Neither procedural complications nor AKI were associated with treatment modality. Among 175 yr of radiographic follow-up in patients with known IAs, 8 de novo aneurysms were found, including 3 that were treated. Of 11 patients with SAH, 7 ruptured in the setting of previously known ADPKD, including 2 with prior angiographic screening and 5 without screening. CONCLUSION:Poor outcomes occurred only with ruptured presentation but were equivalent between treatment modalities. Screening is performed only selectively, and 64% (7 of 11) of patients presenting with SAH had previously known ADPKD.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Wilkinson DA,Heung M,Deol A,Chaudhary N,Gemmete JJ,Thompson BG,Pandey ASdoi
10.1093/neuros/nyy336subject
Has Abstractpub_date
2019-06-01 00:00:00pages
E352-E361issue
6eissn
0148-396Xissn
1524-4040pii
5060409journal_volume
84pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract::Twenty patients who underwent early aneurysm surgery--that is, surgery within 72 hours after rupture--underwent further follow-up examination including magnetic resonance imaging (MRI) of the brain and a comprehensive neuropsychological assessment. Significant statistical correlation between tissue loss as seen on a l...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-198909000-00012
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Arteriovenous malformations in the cranial nerves are very rare, and only one case has been reported in the literature. To our knowledge, this is the first case report of an arteriovenous malformation in the auditory nerve. CLINICAL PRESENTATION:A 30-year-old woman presented with a subarachnoi...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000159720.61145.6e
更新日期:2005-06-01 00:00:00
abstract::A model of rat arteriovenous fistula (AVF) was created using a proximal common carotid artery to distal external jugular vein anastomosis. Anatomical dissections revealed that the external jugular vein is the primary vessel draining intracranial venous blood. Physiological measurements were made with the AVF open and ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199109000-00002
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:To investigate the potential operative morbidity in posteroventral pallidotomy (PVP) for patients with Parkinson's disease. METHODS:We designed a retrospective study that included 796 consecutive patients (mean age, 64.9 yr; male, 559; female, 237) with Parkinson's disease. All PVPs (simultaneous bilateral P...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000047817.60776.5c
更新日期:2003-03-01 00:00:00
abstract::Both the perforating branches--especially the extracerebral segments--and the arachnoidal anatomy at the level of the posterior communicating artery were studied in 60 human brains previously fixed in formalin. The close relationships between this artery and the oculomotor nerve are described, and it is noted that eac...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199005000-00015
更新日期:1990-05-01 00:00:00
abstract::Intracranial gliomas are found in association with von Recklinghausen's neurofibromatosis. However, few truly neonatal lesions have been identified and studied. This case report concerns a 4-month-old child who was found to have a massive thalamic glioma of moderate grade. Four paternal generations had suffered from d...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198312000-00014
更新日期:1983-12-01 00:00:00
abstract::An aneurysm of a persistent primitive hypoglossal artery (PHA) particularly at its junction with the basilar artery, often poses therapeutic problems. This is attributable not only to the size and location of the aneurysm but also to the fact that the persistent PHA is functionally the single artery providing blood in...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:
更新日期:1992-05-01 00:00:00
abstract:OBJECTIVE:To investigate the usefulness of a cellulose acetate polymer (CAP) solution for partial thrombosis of aneurysms. METHODS:We created 14 canine cervical carotid bifurcation aneurysms, 11 of which were subsequently thrombosed partially with CAP solution. We then conducted angiographic and histological investiga...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199805000-00108
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To investigate the potential of novel magnetic resonance (MR) angiographic techniques for the assessment of cerebral arteriovenous malformations. METHODS:Forty patients who were about to undergo stereotactic radiosurgery were prospectively recruited. Three-dimensional, sliding-slab interleaved ky (SLINKY), t...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000279215.07763.a1
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To evaluate clinical usefulness of cerebrospinal fluid stroke volume (SV) assessed in the cerebral aqueduct, via cine phase-contrast magnetic resonance imaging, for predicting outcome after shunt surgery in suspected normal pressure hydrocephalus. METHODS:Thirty-eight patients with suspected normal pressure ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000249208.04344.A3
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:In this literature review, the authors analyze data from previously published studies that evaluated neutral upright spinal alignment (NUSA) from the occiput to the pelvis in asymptomatic individuals. Based on the data for NUSA in asymptomatic volunteers, a new classification is proposed for spinal deformity....
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/01.NEU.0000313120.81565.D7
更新日期:2008-09-01 00:00:00
abstract::A case of postoperative tension pneumocephalus of unusual cause after carotid-ophthalmic artery aneurysm clipping is presented. A second craniotomy for decompression and exploration demonstrated a small fistula in the planum sphenoidale, which presumably had been made when the right optic canal was unroofed during the...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/00006123-198811000-00020
更新日期:1988-11-01 00:00:00
abstract::Eight cases are presented to summarize our experience with patients initially evaluated for the new onset of either seizure activity or focal transient neurological deficits. Each was found to have a normal computed tomographic (CT) scan with and without iodinated contrast infusion. All subsequently returned with a CT...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198707000-00006
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:Many patients with symptomatic Chiari I malformations experience symptom recurrence after surgical decompression. Identification of predictors of outcome is needed to better select patients most likely to benefit from surgical intervention. We examined whether or not cerebrospinal fluid (CSF) flow dynamics as...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000219841.73999.B3
更新日期:2006-07-01 00:00:00
abstract::STRESS ULCERS OCCUR frequently in intensive care unit patients who have intracranial disease. After major physiological stress, endoscopic evidence of mucosal lesions of the gastrointestinal tract appears within 24 hours of injury; 17% of these erosions progress to clinically significant bleeding. Gastrointestinal hem...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-199708000-00017
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Although in the developed world the intracranial pressure (ICP) monitor is considered the standard of care for patients with severe traumatic brain injury (TBI), its usefulness to direct treatment decisions has never been tested rigorously. OBJECTIVE:The primary focus was to conduct a high-quality, randomiz...
journal_title:Neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1227/NEU.0b013e31827276b7
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Distal basilar artery aneurysms represent 5 to 8% of intracranial aneurysms. It is crucial to preserve all of the basilar apex perforating vessels when dissecting in this region. This report is the first to describe a rostral basilar perforating artery that was the anatomic origin of a cerebral...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199608000-00034
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVE:A meta-analysis was performed to evaluate whether a beneficial clinical effect of cervical disk prostheses over conventional cervical diskectomy with fusion exists. METHODS:A literature search was completed ending February 4, 2009, that included the abstract books of recent major spine congresses. All studie...
journal_title:Neurosurgery
pub_type: 杂志文章,meta分析
doi:10.1227/01.NEU.0000369189.09182.5F
更新日期:2010-06-01 00:00:00
abstract::Proton magnetic resonance spectroscopic imaging (1H-MRSI) and positron emission tomography with the tracer L-[1-11C]tyrosine (11C-TYR) were used to localize gliomas for biopsy or resection. This is especially helpful in cases of low-grade gliomas, if these lesions are not visualized by contrast-enhanced computed tomog...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199406000-00007
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Epithelial cysts of the central nervous system are unusual entities, with the majority reported to occur in the spinal canal. More unusual is the intracranial presentation, which shows a predilection for midline localization in the posterior fossa, brainstem, and suprasellar regions. This repor...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:
更新日期:2002-08-01 00:00:00
abstract::Lymphocytic hypophysitis (adenohypophysitis) is a rare lymphocytic infiltration of the pituitary gland that usually occurs during pregnancy. Because of its rarity, it has seldom been diagnosed preoperatively, and no trials of therapeutic treatment have been reported to date. We describe a 29-year-old woman with a pitu...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199202000-00023
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Anterior cingulotomy (AC) can be an effective therapy for patients with severe obsessive-compulsive disorder who are refractory to traditional medical therapy. For patients who do not respond to AC, the benefit of additional lesion procedures vs continued medical management remains unknown. OBJECTIVE:To det...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31827b9c7c
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Treatment of 11 patients with aneurysms or arteriovenous fistulae of the craniocervical arteries with stent grafts. METHODS:Peripheral stent grafts were deployed in two extracranial internal carotid arteries. Coronary stent grafts were used to treat two giant aneurysms, five direct carotid-cavernous fistulae...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000134455.02947.1f
更新日期:2004-09-01 00:00:00
abstract::The purpose of Clinical Problem Solving manuscripts is to present management challenges in an attempt to give practicing neurosurgeons insight into how field leaders address these dilemmas. This illustration is accompanied by a brief review of the literature on the topic. We describe the case of a patient who presente...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/NEU.0b013e3181ee42e7
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To study the biomechanical behavior of lumbar interbody instrumentation techniques using titanium cages as either transforaminal lumbar interbody fusion (TLIF) or anterior lumbar interbody fusion (ALIF), with and without posterior pedicle fixation. METHODS:Six fresh-frozen lumbar spines (L1-L5) were loaded w...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000245609.01732.E4
更新日期:2006-12-01 00:00:00
abstract::Although the shapes of velocity waveforms obtained with transcranial Doppler examination can indicate such abnormalities as increased intracranial pressure and proximal arterial compromise, the significance of unusual waveform morphologies is often obscure. In this report, we describe four cases in which an unusual wa...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199406000-00018
更新日期:1994-06-01 00:00:00
abstract::A case of choroidal epithelial cyst of the prepontine region is reported. The cyst wall was studied using light and electron microscopy. Electron microscopy revealed that the lining of the cyst consisted of a single layer of epithelial cells resting on a basement membrane. The epithelial cells contained numerous club-...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198801010-00021
更新日期:1988-01-01 00:00:00
abstract::Dural arteriovenous fistulas are abnormal connections of dural arteries to dural veins or venous sinuses originating from within the dural leaflets. They are usually located near or within the wall of a dural venous sinus that is frequently obstructed or stenosed. The dural fistula sac is contained within the dural le...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/NEU.0000000000000228
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:For patients with internal carotid artery occlusion with advanced narrowing of the ipsilateral external carotid artery (ECA), we performed preventive carotid endarterectomy (CEA) for the ECA stenosis before superficial temporal artery (STA) to middle cerebral artery (MCA) anastomosis for internal carotid arte...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1227/01.neu.0000326024.93724.16
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To save the patency of the internal carotid artery (ICA) during the treatment of carotid cavernous fistulae or cavernous sinus dural arteriovenous malformations, direct surgery of the cavernous sinus after failure of endovascular treatment was attempted in this study. METHODS:A total of 78 patients with caro...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199710000-00006
更新日期:1997-10-01 00:00:00