[Generalized immune-complex vasculitis combined with pulmonary hemosiderosis and dilated cardiomyopathy].

Abstract:

:The paper is concerned with observations over 3 patients in whom unusual vasculitis lay at the basis of the clinicopathological manifestations. All the patients were men of the young age. The disease debut was marked by fever, weakness, dyspnea, palpitation, cough, hemoptysis, the articulation syndrome. In two cases, there was hemorrhagic rash on the leg skin. All the patients manifested liver and spleen enlargement, two patients had lymphoadenopathy. The leading clinical symptoms included dilated cardiomyopathy, complete blockade of the inferior peduncle of His bundle and reduction of myocardial contractility. Anemia belonged to iron deficient one. The clinical examples provided indicate that immunocomplex vasculitis with evident lesions of the lungs and myocardium, not going into criteria for the known diseases, is not likely to be a casuistic rarity. Those syndromes may be associated with more or less pronounced hemosiderosis of the lungs (and, probably, of the lymph nodes, spleen and liver), with transitory or steady derangements of myocardial conduction, which attests to diffuse lesions of the myocardium possibly with both immune complexes and hemosiderin. The pathology requires further studies.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Margulis EIa,Savchenko VG,Idel'son LI,Pashkov VV,Smirnov AN,Vasil'ev SA,Titarenko MF,Zhirova NF

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

143-8

issue

7

eissn

0040-3660

issn

2309-5342

journal_volume

62

pub_type

杂志文章
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  • [The dynamic echocardiographic indices after restoration of the sinus rhythm in patients with the compensated type of atrial fibrillation].

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