Unprecedented formation of palladium(II)-pyrazole based thiourea from chromone thiosemicarbazone and [PdCl2(PPh3)2]: Interaction with biomolecules and apoptosis through mitochondrial signaling pathway.

abstract：:A combination of magnetic circular dichroism (MCD), electronic absorption spectroscopy and time-dependent density functional theory (TD-DFT) calculations has been used to investigate the electronic structure of azulene-fused pi-expanded porphyrins based primarily on the spectral properties of absorption bands in the n...

journal_title：Journal of inorganic biochemistry

authors： Nakai K,Kurotobi K,Osuka A,Uchiyama M,Kobayashi N

更新日期：2008-03-01 00:00:00

abstract：:We investigated new development in photodynamic therapy (PDT), aiming at enhanced tumor selectivity and biocompatibility, which included application of a third-generation photosensitizing agent, i.e. xanthene-origin Rose Bengal (RB) co-encapsulated with up-converting NaYF4 nanoparticles (NPs) co-doped with lanthanide ...

journal_title：Journal of inorganic biochemistry

authors： Bazylińska U,Wawrzyńczyk D,Szewczyk A,Kulbacka J

更新日期：2020-07-01 00:00:00

abstract：:The magnetic properties of intact and freeze-dried blood cells of the tunicate Ascidia nigra and of model vanadium(III) and (IV) compounds as polycrystalline solids and in aqueous solution have been measured up to 50 kOe with a SQUID susceptometer. Corrections for the samples' diamagnetism were extracted from the temp...

journal_title：Journal of inorganic biochemistry

authors： Lee S,Kustin K,Robinson WE,Frankel RB,Spartalian K

更新日期：1988-07-01 00:00:00

abstract：:With the aim to investigate the mechanism of Cu(I) transport by Wilson ATPase (ATP7B), we have studied the interaction of the peptides 2K10p (CH(3)CO-Lys-Gly-Met-Thr-Cys-Ala-Ser-Cys-Val-His-Asn-Lys-CONH(2)), and 2K8p (CH(3)CO-Lys-Leu-Cys-Ile-Ala-Cys-Pro-Cys-Ser-Lys-CONH(2)), part of the sixth metal binding domain (WD6...

journal_title：Journal of inorganic biochemistry

authors： Myari A,Hadjiliadis N,Fatemi N,Sarkar B

更新日期：2004-09-01 00:00:00

abstract：:This communication presents synthesis and spectral characterization of metalloporphyrin [Zn(X)TMPyP4] (TMPyP4 is 5,10,15,20-tetrakis (N-methylpyridinium-4-yl)porphyrin), and studies its binding onto anionic surface sites of synthetic double stranded polynucleotide Poly(A)-Poly(U). [Zn(X)TMPyP4] binding with Poly(A)-Po...

journal_title：Journal of inorganic biochemistry

authors： Tolstykh G,Sizov V,Kudrev A

更新日期：2016-08-01 00:00:00

abstract：:L-Cysteinatogold(I) was prepared by the reaction of L-cysteine with KAuBr4 in acidic media and its solubility determined from pH 4 to 10. The solubility at pH 7.4 and 37 degrees C is 1 microM. In the presence of excess cysteine, the solubility increases because of formation of bis(L-cysteinato)gold(I). The equilibrium...

journal_title：Journal of inorganic biochemistry

authors： Shaw CF 3rd,Schmitz G,Thompson HO,Witkiewicz P

更新日期：1979-07-01 00:00:00

abstract：:Ten new vanadocene complexes bearing N,N'-chelating ligands were prepared, characterized, and their cytotoxicity toward a panel of cancer cells was measured. Structures of four vanadocene compounds were determined by single crystal X-ray diffraction analysis. Complexes containing 1,2-bis(phenylimino)acenaphthene (bian...

journal_title：Journal of inorganic biochemistry

authors： Melounková L,Machálková A,Havelek R,Honzíček J,Řezáčová M,Císařová I,Peterová E,Vinklárek J

更新日期：2019-06-01 00:00:00

abstract：:Metallodrugs have become an integral part of modern medicinal chemistry with platinum drugs as anti-cancer agents being well-known examples. The historically interesting compound Zeise's salt, potassium trichlorido(ethene)platinate(II) has scarcely been investigated in this context yet. This study is geared towards sh...

journal_title：Journal of inorganic biochemistry

authors： Cziferszky M,Gust R

更新日期：2018-12-01 00:00:00

abstract：:Positional isomers of mono-unsaturated 18:1-ACP have been used as substrates for stearoyl-acyl carrier protein delta9 desaturase to test whether a C-H bond abstraction from either the C-9 or C-10 position could lead to rearranged products diagnostic for the production of an allylic radical intermediate. The reconstitu...

journal_title：Journal of inorganic biochemistry

authors： Broadwater JA,Laundre BJ,Fox BG

更新日期：2000-01-15 00:00:00

abstract：:1,2-diolato ligands, such as carbohydrates and glycoproteins, tend to stabilize chromium(V), thus forming important intermediates that have been implicated in the genotoxicity of Cr(VI). Since many years, room-temperature continuous-wave electron paramagnetic resonance (EPR) at X-band microwave frequencies has been us...

journal_title：Journal of inorganic biochemistry

authors： Van Doorslaer S,Beirinckx Q,Nys K,Mangiameli MF,Cuypers B,Callens F,Vrielinck H,González JC

更新日期：2016-09-01 00:00:00

abstract：:The clinical efficiency of Pt(II)-based drugs is founded on articulate mechanisms of action. Indeed it depends on a balanced combination of metal ion reactivity towards proteins and nucleic acids. Here we analysed the effect of two trans-platinum planar amines in comparison to cisplatin and transplatin on the DNA proc...

journal_title：Journal of inorganic biochemistry

authors： Pinato O,Benettazzo A,Dalla Via L,Farrell NP,Sissi C

更新日期：2020-10-01 00:00:00

abstract：:The relationship between respiratory and neurological effects of exposure to aluminium (Al) was investigated in a group of foundry workers exposed to Al at concentrations below the threshold limit value (TLV) binding in Poland (2.0 mg Al2O3 m(-3)). Neurological and neurophysiological parameters indicated subclinical e...

journal_title：Journal of inorganic biochemistry

authors： Halatek T,Sinczuk-Walczak H,Rydzynski K

更新日期：2005-09-01 00:00:00

abstract：:Raman spectra were acquired on ox femur samples treated with hydrazine to remove the organic components of bone. A large increase in the signal-noise ratio of the mineral spectrum resulted from the exposure of the mineral surface and the removal of fluorescent components of the organic matrix. The effect of hydrazine ...

journal_title：Journal of inorganic biochemistry

authors： Walters MA,Leung YC,Blumenthal NC,LeGeros RZ,Konsker KA

更新日期：1990-07-01 00:00:00

abstract：:In an effort to understand the biochemical mechanisms of aluminum-induced neurotoxicity, we investigated the effects of aluminum ion, Al3+, on the Mg(2+)- and nucleotide-dependent protein, ras p21. Picomolar Al3+ concentrations inhibited the GTPase activity of ras p21 in an Mg(2+)-dependent manner, consistent with an ...

journal_title：Journal of inorganic biochemistry

authors： Landino LM,Macdonald TL

更新日期：1997-05-01 00:00:00

abstract：:Boosting the photosensitization type I process will enhance the phototherapy efficacy because the superoxide radicals (O2-) generated during type I process are more toxic than the singlet oxygen (1O2) in type II process. Herein, [Ru(Hdtza)(phen)2][PF6] (1) and [Ru(pytz)(phen)2][PF6] (2) (phen = 1,10-phenanthroline) ba...

journal_title：Journal of inorganic biochemistry

authors： Zhang X,Huang X,Xie A,Zhang X,Deng J,Zou D,Zou J

更新日期：2020-11-01 00:00:00

abstract：:Nitroxyl (HNO) has gained interest as a potential treatment of congestive heart failure through the ability of the HNO donor, Angeli's salt (AS), to evoke positive inotropic effects in canine cardiac muscle. The release of nitrite during decomposition limits the use of AS requiring other HNO sources. Acyloxy nitroso c...

journal_title：Journal of inorganic biochemistry

authors： DuMond JF,Wright MW,King SB

更新日期：2013-01-01 00:00:00

abstract：:Nearly all microbes require iron for growth. The low concentration of iron found in the ocean makes iron acquisition a particularly difficult task. In response to these low iron conditions, many bacteria produce low-molecular-weight iron-binding molecules called siderophores to aid in iron uptake. We report herein the...

journal_title：Journal of inorganic biochemistry

authors： Gauglitz JM,Zhou H,Butler A

更新日期：2012-02-01 00:00:00

abstract：:We prepared and characterized new iridium(III) complexes: [Ir(NC)2(MPPIP)](PF6) (N-C = 2-phenylpyridine 1; benzo[h]quinolone 2; 1-phenylisoquinolone, 3, MPPIP = 2-(4-(4'-methylpiperazin-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline). MTT (MTT = 3-(4,5-dimethylthiazole-2-yl)-2,5-biphenyl tetrazolium bromide) method ...

journal_title：Journal of inorganic biochemistry

authors： Gu Y,Wen H,Bai L,Zhou Y,Zhang H,Tian L,Zhang Y,Hao J,Liu Y

更新日期：2020-11-01 00:00:00

abstract：:The coordination chemistry of the one-electron reduced form of nitric oxide, termed a nitroxyl or nitrosyl hydride (NO- or HNO), is described with special focus on its interaction with hemes and heme model complexes. Nitroxyl intermediates have been proposed in the catalytic cycles of several heme-based nitrite and ni...

journal_title：Journal of inorganic biochemistry

authors： Farmer PJ,Sulc F

更新日期：2005-01-01 00:00:00

abstract：:Iron is an essential nutrient for most bacteria. Depending on the oxygen available in the surrounding environment, iron is found in two distinct forms: ferrous (Fe(II)) or ferric (Fe(III)). Bacteria utilize different transport systems for the uptake of the two different forms of iron. In oxic growth conditions, iron i...

journal_title：Journal of inorganic biochemistry

authors： Carpenter C,Payne SM

更新日期：2014-04-01 00:00:00

abstract：:The novel anticancer drug ([[trans-PtCl(NH(3))(2)](2)-mu-[trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2)]](NO(3))(4)) (BBR3464, 1,0,1/t,t,t, TPC) forms a 1,4-interstrand cross-linked adduct with the self-complementary DNA octamer 5'-d(ATG*TACAT)(2)-3', with the two platinum atoms coordinated in the major groove at N7 pos...

journal_title：Journal of inorganic biochemistry

authors： Qu Y,Scarsdale NJ,Tran MC,Farrell N

更新日期：2004-10-01 00:00:00

abstract：:Three-week-old Picea abies seedlings were grown for 7 days in 100 microM aluminium (Al), combined with 1000 or 2000 microM silicon (Si). Solution pH was adjusted to 4.00, 4.25, 4.50, 4.75, or 5.00. In the absence of Si, solution pH had no effect on the decrease in root growth caused by 100 microM Al. Silicon did not a...

journal_title：Journal of inorganic biochemistry

authors： Ryder M,Gérard F,Evans DE,Hodson MJ

更新日期：2003-09-15 00:00:00

abstract：:Cadmium ions applied to either (outer or inner) surface of the isolated toad skin dose-dependently increased the short-circuit current (SCC), the potential difference (V) and the active sodium conductance (G(Na)) in the concentration range 0.07-0.50mM. Maximal stimulatory effect was over 30% with an EC(50) of about 0....

journal_title：Journal of inorganic biochemistry

authors： Suwalsky M,Norris B,Cárdenas H

更新日期：2005-12-01 00:00:00

abstract：:We have used low-temperature (77K) resonance Raman (RR) spectroscopy as a probe of the electronic and molecular structure to investigate weak pi-pi interactions between the metal ion-coordinated His imidazoles and aromatic side chains in the second coordination sphere of blue copper proteins. For this purpose, the RR ...

journal_title：Journal of inorganic biochemistry

authors： Fitzpatrick MB,Obara Y,Fujita K,Brown DE,Dooley DM,Kohzuma T,Czernuszewicz RS

更新日期：2010-03-01 00:00:00

abstract：:An iron porphycene, a structural isomer of iron porphyrin, with trifluoromethyl groups at the peripheral position of the framework was incorporated into sperm whale apomyoglobin. The prepared myoglobin shows the higher O(2) affinity than the native protein. However, the oxygen affinity of the reconstituted myoglobin i...

journal_title：Journal of inorganic biochemistry

authors： Matsuo T,Ito K,Nakashima Y,Hisaeda Y,Hayashi T

更新日期：2008-02-01 00:00:00

abstract：:Vanadium compounds have arisen as potential therapeutic agent for the treatment of cancers over the past decades. A few studies suggested that vanadyl complexes may discriminate between the cancerous and the normal cells. Here, we reported the investigation on the pro-apoptotic effect and the underlying mechanism of b...

journal_title：Journal of inorganic biochemistry

authors： Zhang Y,Wang L,Zeng K,Wang K,Yang X

更新日期：2018-11-01 00:00:00

abstract：:The uptake of chromate by the duckweed Spirodela polyrhiza was investigated with atomic absorption spectroscopy and the reduction of Cr(VI) to Cr(V) was measured using low frequency EPR spectroscopy. The biphasic kinetics of the uptake was fitted to parameters of a proposed kinetic model. Another model was developed t...

journal_title：Journal of inorganic biochemistry

authors： Appenroth KJ,Bischoff M,Gabryś H,Stoeckel J,Swartz HM,Walczak T,Winnefeld K

更新日期：2000-02-01 00:00:00

abstract：:Electron paramagnetic resonance (e.p.r.) studies of thin DNA-chelate films indicate that both the water soluble planar macrocyclic chelates, cobalt (II) tetra (2,3-N-methylpyridinium) porphyrazine (cobalt (II) TMTPPA), and vanadyl (II) 5,10,15,20-tetra-(4-methylpyridinium) porphyrin (Vo (II) TMTPyP) can bind to calf t...

journal_title：Journal of inorganic biochemistry

authors： Dougherty G

更新日期：1988-10-01 00:00:00

abstract：:The antitumoral potential for a series of platinum iodido complexes, all bearing the same aliphatic amines (first iodido complexes generation), was demonstrated in a previous study. Concretely, cis complexes were shown to have a peculiar and different reactivity compared to cisplatin with sulfur donors models and Cyt ...

journal_title：Journal of inorganic biochemistry

authors： Parro T,Medrano MA,Cubo L,Muñoz-Galván S,Carnero A,Navarro-Ranninger C,Quiroga AG

更新日期：2013-10-01 00:00:00

abstract：:Acute promyelocytic leukemia (APL) is characterized and driven by the promyelocytic leukemia protein-retinoic acid receptor alpha (PML-RARα) fusion gene. Previous studies have highlighted the importance of PML-RARα degradation in the treatment against APL. Considering the presence of two zinc fingers in the PML-RARα f...

journal_title：Journal of inorganic biochemistry

authors： Zhu B,Wang JY,Zhou JJ,Zhou F,Cheng W,Liu YT,Wang J,Chen X,Chen DH,Luo L,Hua ZC

更新日期：2017-10-01 00:00:00