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Leukocytosis after distal pancreatectomy and splenectomy as a marker of major complication.

Abstract：

BACKGROUND:The aim of this study was to analyze the associations between the degree of postoperative leukocytosis and major morbidity after elective distal pancreatectomy with splenectomy (DPS). METHODS:Retrospective review of patients undergoing DPS for pancreatic diseases (2013-2016). Receiver operating characteristic curves, Youden's index, and area under the curve were used to identify ideal lab cut-off values and discriminatory ability of postoperative white blood cell count to detect complications. RESULTS:158 patients underwent DPS. Median age was 57 years (range, 22-90) and 53% of patients were male. POD3 absolute WBC count ≥16 × 109/L or an increase in WBC count ≥9 × 109/L from preoperative baseline was associated with major morbidity after DPS (AUC 0.7 and 0.7, respectively). CONCLUSION:Postoperative day three leukocytosis ≥16 × 109/L or an increase in WBC of ≥9 × 109/L from preoperative baseline should raise clinical awareness for major postoperative complication after DPS.

journal_name

Am J Surg

journal_title

American journal of surgery

authors

Maatman TK,Butler JR,Quigley SN,Loncharich AJ,Crafts T,Ceppa EP,Nakeeb A,Schmidt CM,Zyromski NJ,House MG

doi

10.1016/j.amjsurg.2019.12.004

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

354-358

issue

2

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(19)31555-7

journal_volume

220

pub_type

杂志文章

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