Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period.

Abstract:

BACKGROUND:The purpose of this study was to analyze the influence of age on both the risk of hepatectomy and the prognosis in patients with hepatocellular carcinoma (HCC). METHODS:Patients undergoing an initial hepatectomy for HCC were classified into 2 age groups: 75 years or over (n = 113) and less than 75 years (n = 499). RESULTS:A zero 90-day mortality was achieved in the elderly. Although the recurrence rate and recurrence sites were almost similar between the 2 groups, the 5-year survival rate in the elderly patients was significantly lower than that in the younger patients (46.0% vs 57.6%; P = .018), possibly because of the higher incidence of deaths from other causes (26.8% vs 10.4%; P = .011) in the elderly. CONCLUSION:Selected elderly HCC patients can undergo a hepatectomy safely and can benefit from long-term HCC control comparable with that of their younger counterparts.

journal_name

Am J Surg

authors

Motoyama H,Kobayashi A,Yokoyama T,Shimizu A,Sakai H,Furusawa N,Notake T,Kitagawa N,Arai T,Yokoi K,Okubo Y,Miyagawa S

doi

10.1016/j.amjsurg.2014.05.026

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

733-41

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(14)00365-1

journal_volume

209

pub_type

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