Association of pre-operative medication use with unplanned 30-day hospital readmission after surgery in oncology patients receiving comprehensive geriatric assessment.

Abstract:

BACKGROUND:This study aimed to determine whether pre-operative medication use is associated with unplanned 30-day readmission in elderly people undergoing cancer surgery. METHODS:Patients aged 65 years or older who were scheduled for cancer surgery and presented for comprehensive geriatric assessment were included. Comparisons of variables between patients with readmission and those without readmission were performed by univariate and multivariate analyses. RESULTS:A total of 473 patients were included. Multivariate analysis showed that pre-operative discontinuation-requiring medications (PDRMs) and gastrointestinal/hepato-pancreato-biliary (GI/HPB) cancer were significant factors for 30-day readmission. PDRM increased the risk of readmission by about 2.2-fold. Attributable risk of PDRM to readmission was around 55%. The adjusted odds ratio and attributable risk for GI/HPB surgery was 3.4 (95% CI 1.0-11.5) and 70.8%, respectively. CONCLUSIONS:Medication use has an impact on unplanned 30-day readmission in geriatric oncology patients, further highlighting the importance of medication optimization for elderly patients with cancer surgery.

journal_name

Am J Surg

authors

Jeon MS,Jeong YM,Yee J,Lee E,Kim KI,Lee BK,Rhie SJ,Chung JE,Gwak HS

doi

10.1016/j.amjsurg.2019.06.020

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

963-968

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(18)31185-1

journal_volume

219

pub_type

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