The influence of race on the development of acute lung injury in trauma patients.

Abstract:

BACKGROUND:Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality. METHODS:Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center. RESULTS:African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao(2)/Fio(2)) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race. CONCLUSIONS:Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.

journal_name

Am J Surg

authors

Brown LM,Kallet RH,Matthay MA,Dicker RA

doi

10.1016/j.amjsurg.2010.02.003

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

486-91

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(10)00234-5

journal_volume

201

pub_type

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