Fetomaternal Hemorrhage: Can We Use Hemoglobin Electrophoresis as a Diagnostic Tool?

Abstract:

:Fetomaternal hemorrhage (FMH) is usually detected by either the Kleihauer-Betke (KB) test or by 2 cytometry, the latter of which represents the gold standard of FMH diagnosis today. But what do we do when neither method is available? We present two cases of suspected FMH due to their characteristic signs and symptoms that were ultimately confirmed by hemoglobin electrophoresis (HE). :Fetomaternal hemorrhage (FMH) is usually detected by either the Kleihauer-Betke (KB) test or by 2 cytometry, the latter of which represents the gold standard of FMH diagnosis today. But what do we do when neither method is available? We present two cases of suspected FMH due to their characteristic signs and symptoms that were ultimately confirmed by hemoglobin electrophoresis (HE).

authors

Stanic Z,Stanisic L,Fureš R,Persec Z,Dapic K,Hrgovic Z

doi

10.1055/a-1041-3443

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

150-152

issue

3

eissn

0948-2393

issn

1439-1651

journal_volume

224

pub_type

杂志文章
  • [Changes in umbilical cord blood acid-base status after delivery in dependence on time intervall--a continuing forensic problem].

    abstract:BACKGROUND:The time window for measuring blood gases in the umbilical cord after birth is often discussed controversial with regard to birth damage claims. METHODS:53 umbilical cords from spontaneous deliveries at term were double clamped at room temperature directly after birth and paired arterial and venous samples ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0032-1323794

    authors: Butterwegge M,Kappen R,Rath W

    更新日期:2012-12-01 00:00:00

  • [Accuracy of prenatal diagnoses in terminated pregnancies--a retrospective analysis of results and influences].

    abstract:OBJECTIVE:The aim of the study was to analyse the accuracy of prenatal sonography in terminated pregnancies and the influence of factors like personnel and standard of technique and organisation on the quality of prenatal sonography for the detection of fetal anomalies. MATERIAL AND METHODS:The retrospective study inc...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2001-14821

    authors: Faber R,Stepan H,Schilde M,Froster UG,Horn LC

    更新日期:2001-03-01 00:00:00

  • [Legal situation of the locum in the field of obstetrics or the question as to who is liable for what and when?].

    abstract::With regard to the question of the liability of a locum, the contractual general conditions are important above all others for the locum. The false opinion of some physicians that one is not liable because one is on holiday - or at least was not concretely involved in the incident - can, from case to case, be misleadi...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1287859

    authors: Ratzel R

    更新日期:2011-12-01 00:00:00

  • [Ambulant Management in Case of Premature Rupture of Membranes (PROM) at Term: Maternal and Perinatal Outcome].

    abstract::Introduction: It is estimated that after premature rupture of membranes (PROM) at term, 60% of all women go into labour within 48 h, 95% within 72 h. Often labour is induced after 24 h because the risk of maternal and neonatal infection rises. The majority of clinicians advise hospital care to allow monitoring and det...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0042-115035

    authors: Vetter G,Knipprath A,Niklaus A,Kalberer N,Hösli I

    更新日期:2016-10-01 00:00:00

  • [Results of the hypothermia registry of the University Hospital Dresden from 2010-2017. Application of hypothermia therapy in newborns in Germany].

    abstract:INTRODUCTION:Therapeutic hypothermia (TH) improves the outcome in newborns with hypoxic-ischemic encephalopathy (HIE) and should be used in case of perinatal asphyxia and signs of moderate/severe HIE. MATERIAL/METHODS:Frequency of HIE and the application of TH were extracted from the neonatal survey, a registry that c...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-1164-7174

    authors: Scherer J,Whybra-Trümpler C,Mildenberger E

    更新日期:2020-12-01 00:00:00

  • [Influence of antenatal acupuncture on cardiotocographic parameters and maternal circulation - a prospective study].

    abstract:BACKGROUND:Acupuncture as a non-evidence-based therapy modality is widely used in obstetrics prior to and during delivery. Thus far, only few studies investigated the impact of acupuncture on obstetric surveillance parameters like cardiotocography. The aim of this study was to control the effect of clearly-defined acup...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2003-43416

    authors: Scharf A,Staboulidou I,Günter HH,Wüstemann M,Sohn C

    更新日期:2003-09-01 00:00:00

  • [Umbilical Absent and Reverse End-Diastolic Flow Velocity Waveforms Already Present Prior to Viability do not Exclude Long-Term Foetal Surveillance: A Report of Two Cases].

    abstract::The finding of absent or reverse end-diastolic flow velocities (AREDV) in the umbilical artery already prior to viability corresponds to the most severe end of the clinical spectrum of placental insufficiency. However, there is little or no experience or published literature with regard to perinatal outcome. We report...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1394388

    authors: Müller T,Wirbelauer J,Frauenschuh I,Frambach T,Zollner U,Dietl J

    更新日期:2015-04-01 00:00:00

  • [Prevention of complications in twin gestations and pregnancies after assisted reproduction].

    abstract:BACKGROUND:Twin pregnancies and gestations after assisted reproductive therapy (ART) are of special obstetric significance with regard to their associated risks. However, little is known about preventive approaches specifically evaluated for these constellations. METHODS:A selective literature search was conducted to ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0029-1241846

    authors: Luedders DW,Hornemann A,Fritzsching B,Thill M,Beyer DA,Diedrich K,Bohlmann MK

    更新日期:2009-12-01 00:00:00

  • [Evaluation of quantitative ultrasonometry of bone in singleton and multiple pregnancies].

    abstract:OBJECTIVE:During pregnancy about 30 grams of calcium are transferred to a full-term neonate. The enormous demand for calcium can be regulated by compensatory mechanisms in the maternal metabolism such as elevated steroid hormone levels, increased intestinal absorption of dietary calcium, and renal conservation, but als...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2006-951742

    authors: Hellmeyer L,Anderer G,Ziller V,Wagner U,Schmidt S,Hadji P

    更新日期:2006-10-01 00:00:00

  • [Episiotomy and its complications].

    abstract::1. Many benefits claimed for episiotomy are not sufficiently proven. In recent literature, some of them are questioned and some have been disproven. 2. Episiotomy, especially median episiotomy, has a higher risk of third-degree lacerations. Mediolateral episiotomy is more often followed by postpartum pain and impaired...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:

    authors: Hirsch HA

    更新日期:1997-01-01 00:00:00

  • [Artificial amniotic fluid instillation in premature rupture of fetal membranes and extreme prematurity as alternative therapy].

    abstract::We report two cases of premature rupture of membranes and oligohydramnios (gestational age: 23rd/24th week). In both pregnancies artificial instillation of amniotic fluid (AIF) was performed once a week. We hypothesize that fetal head compression with impaired cerebral perfusion due to oligohydramnios causes periventr...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Faber R,Robel-Tillig E,Vogtmann C,Stepan H,Viehweg B

    更新日期:1999-07-01 00:00:00

  • [Prevention of preterm birth by Shirodkar cerclage--clinical results of a retrospective analysis].

    abstract::In spite of the continuous progress in prenatal care, 1 out of 10 babies is born too early--tendency rising worldwide. As a consequence of the heterogeneous aetiology of preterm birth, there is still no single and efficient interventional therapy. Cerclage is one option for pregnancies with cervical insufficiency, whe...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0034-1382070

    authors: Schubert RA,Schleussner E,Hoffmann J,Fiedler A,Stepan H,Gottschlich A

    更新日期:2014-08-01 00:00:00

  • The Effect of Asthma Severity on Perinatal Outcomes: A Tertiary Hospital Experience.

    abstract:OBJECTIVE:To evaluate the effect of asthma severity and disease exacerbation on pregnancy outcomes. MATERIALS AND METHODS:Pregnancies were classified into 3 groups as mild (n=195), moderate (n=63), and severe (n=26) according to preconceptional asthma severity. Demographic features, clinical characteristics, and perin...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-1264-8207

    authors: Tanacan A,Fadiloglu E,Celebioglu ED,Orhan N,Unal C,Celik T,Kalyoncu AF,Beksac MS

    更新日期:2020-10-14 00:00:00

  • [Ear acupuncture points in newborn triplets].

    abstract::The current study demonstrates for the first time the presence of ear acupuncture points in prematurely delivered triplets of 31 weeks and two days gestational age. Pregnancy was an IVF pregnancy and caesarean section was performed because of preeclampsia. Ear acupuncture points were determined with the Svesa point se...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2007-960676

    authors: Stähler van Amerongen K,Kuhn A,Surbek D,Nelle M

    更新日期:2007-04-01 00:00:00

  • Geburtshilfliche Notfälle – eine neue Serie zum Neuen Jahr.

    abstract::Liebe Leserinnen und Leser,vielleicht befinden Sie sich in der Ausbildung zum Facharzt für Gynäkologie und Geburtshilfe oder erinnern sich noch gut daran. Ein großer Anteil der Weiterbildung findet in einer Klinik statt, und man fürchtet den ersten Dienst. Man steht am Kreißbett und ist stets respektvoll gespannt, geb...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-0734-4708

    authors: de Sousa MT

    更新日期:2018-12-01 00:00:00

  • [PIBF - Progesterone-Induced Blocking Factor].

    abstract::Pregnancy is a unique immunological situation in which 2 allogeneic organisms live in intimate symbiosis without developing rejection reactions. At different locations, interfaces exist between mother and foetus with direct contact between both individuals: 1) maternal blood surrounds foetal villi, which are covered w...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1271742

    authors: Ermisch C,Markert UR

    更新日期:2011-06-01 00:00:00

  • [Massive placental hemorrhage in partial molar pregnancy due to hypotriploidy (68,XX)--prenatal diagnosis and clinical course].

    abstract:BACKGROUND:Triploidy describes the presence of threefold haploid chromosome set and is a frequent cause of early abortion. Only few pregnancies reach the second trimester. CASE REPORT:Prenatal diagnosis of a fetus in the 28th week of gestation with a hypotriploidy and with characteristic ultrasonographic features is p...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2001-15769

    authors: Henrich W,Schmider A,Sarioglu N,Neitzel H

    更新日期:2001-05-01 00:00:00

  • [Fetal monitoring intra partum with cardiotocography and fetal blood sampling analysis and its possible influence on the C-section rate].

    abstract::In times of rising c-section rates worldwide the obstetricians feel a big responsibility in avoiding a secondary c-section for non-reassuring fetal heart rate. No other experimental method has been established beside the gold standard (cardiotocography and fetal blood sampling) in daily routine until today. The two ca...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2004-818961

    authors: Butterwegge M

    更新日期:2004-04-01 00:00:00

  • Cardiac Etiologies of Hydrops Fetalis.

    abstract::Cardiac etiologies of hydrops fetalis have been a topic of concern due to challenging perinatal management. The common cardiac etiologies leading to hydrops fetalis include structural cardiac anomalies, cardiac dysrhythmias, cardiac tumors, cardiomyopathy and myocarditis. The mechanisms of cardiogenic hydrops fetalis ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-123825

    authors: Yuan SM

    更新日期:2017-04-01 00:00:00

  • Zum Beitrag: Frühgeburtenrate in 6 Perinatalzentren in Baden-Württemberg – Potenzial zur Reduktion der Frühgeborenenzahl.

    abstract::Frühgeburtenrate in 6 Perinatalzentren in Baden-Württemberg – Potential zur Reduktion der Frühgeborenenzahl Sehr geehrte Damen und Herren,mit großem Interesse haben wir die Arbeit von Trotter et al. 1 gelesen und teilen die Auffassung, dass eine Vermeidung von Frühgeburten und eine Reduzierung der Frühgeburtenrate unb...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-0950-6770

    authors: Rossi R,Heller G,Maier RF

    更新日期:2019-08-01 00:00:00

  • [Periodontal diseases--a review on the association between maternal periodontitis and adverse pregnancy outcome].

    abstract::Several prospective clinical trials have indicated an association between maternal periodontal status and adverse pregnancy outcome, e.g., low birth weight, pre-term birth and pre-eclampsia. However, the translation of these findings into clinical care and decision making is still a matter of debate. Gynecologists and...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1385859

    authors: Manegold-Brauer G,Hoesli I,Brauer HU,Beikler T

    更新日期:2014-12-01 00:00:00

  • Fetal Valproate Syndrome - Still a Problem Today!

    abstract::Introduction Fetal exposition to valproate can lead to a cluster of facial dysmorphism, congenital anomalies and neurodevelopmental retardation. Case Report In this report we describe 2 cases of fetal valproate syndrome. In the first case, the gravida had a valproate medication before and during pregnancy with additio...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0043-107619

    authors: Wiedemann K,Stüber T,Rehn M,Frieauff E

    更新日期:2017-10-01 00:00:00

  • [Angiogenic factors and their role in pathogenesis and prediction of preeclampsia].

    abstract::Angiogenic factors like placental growth factor (PlGF) and its anti-angiogenic antagonists soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng) are closely related to the pathogenesis of preeclampsia and intrauterine growth restriction (IUGR). The discovery and investigation of these angiogenic facto...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1224142

    authors: Stepan H,Jank A

    更新日期:2009-06-01 00:00:00

  • Overview Tumour Disease and Oncologic Therapy During Pregnancy.

    abstract::Newly diagnosed cancer in pregnancy is an issue with increasing importance, because fulfilling the wish to have a child is shifted later in life. Tumour disease is diagnosed in around 0.1% of all pregnancies in Germany. Most common tumour entities involve the breast, the cervix and the hematopoietic system. As tumour ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0044-100259

    authors: Findeklee S

    更新日期:2018-04-01 00:00:00

  • [Intrauterine growth retardation--perinatal mortality and postnatal morbidity in a perinatal center].

    abstract:OBJECTIVES:The intrauterine growth retardation (IUGR) contributes specially to perinatal mortality and morbidity. An effective treatment is not yet available. The purpose of this study is to analyse the perinatal data of a cohort with IUGR-infants including mortality and morbidity and to describe prematurity and IUGR a...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2000-9581

    authors: Meyberg R,Boos R,Babajan A,Ertan AK,Schmidt W

    更新日期:2000-11-01 00:00:00

  • Prenatal immunomodulation treatment in neonatal myasthenia gravis.

    abstract::Neonatal mysthenia gravis (NMG) is a rare cause of arthrogryposis multiplex congenita (AMC) due to diaplacental transfer of maternal acetylcholine receptors (AChR) antibodies. 2 cases of severe NMG complicated by chronic lung disease and pulmonary arterial hypertension are reported. With respect to the severe course o...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0033-1349888

    authors: Welcker S,Heckmann M,Axt-Fliedner R,Faas D

    更新日期:2013-08-01 00:00:00

  • [How does the Degree of Acculturation Influence the Intention to Breastfeed, Breastfeeding Frequency, and Breastfeeding Duration in Migrant Women? A Review of the Publications from 2014-2018].

    abstract::The breastfeeding behavior of women is influenced by social, demographic and cultural factors, yet little is known about the influence of migration and acculturation. A systematic search using the electronic databases LIVIVO and MEDLINE (PubMed) was conducted followed by a manual search in the bibliographies of all se...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/a-0821-6070

    authors: Kanatoula DD,Brenne S,David M

    更新日期:2019-10-01 00:00:00

  • [Management of dichorionic twin delivery at term with cephalic-presenting first twin - a monocentric retrospective cohort study].

    abstract:OBJECTIVE:To assess neonatal outcome and delivery mode in dichorionic twin delivery at term with a cephalic-presenting first twin. METHODS:A retrospective cohort study of 308 twin deliveries after 37 completed weeks of gestation with a cephalic-presenting first twin undertaken in one perinatal center with active manag...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1267218

    authors: Dudenhausen JW,Golic M,Kirschner R,Brauer M

    更新日期:2010-10-01 00:00:00

  • Konsens und Dissens im gemeinsamen Bestreben um Qualität.

    abstract::Liebe Leserinnen und Leser,Schwangerschaft und Geburt als existentielle Erfahrungen im Leben einer Frau können nicht nur das meist antizipierte Gefühl von Glück und Vollendung oder die oft etwas unerwartete Neuordnung von Lebensplan und Partnerschaft nach sich ziehen, sie können sich in einzelnen Fällen auch psychisch...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 社论

    doi:10.1055/a-0659-7869

    authors: Singer D

    更新日期:2018-10-01 00:00:00

  • [Ultrasound diagnosis of periventricular leukomalacia].

    abstract::Periventricular leucomalacia (PVL) is the most common form of hypoxemic brain damage in infants. In PVL, there is usually a preceding history of asphyxia or hypoxia. This results in hypoxic-ischaemic damage to the region of the brain around the lateral ventricles, a particularly vulnerable area as it is in a border zo...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:

    authors: Staneva KN,Bartolomaeus G

    更新日期:1997-03-01 00:00:00