Evaluation of pooling strategies for acute HIV-1 infection screening using nucleic acid amplification testing.

Abstract:

:A 128-member specimen pooling scheme for acute HIV infection (AHI) detection was evaluated using 21 AHI specimens (range, 1,520 to 500,000 copies/ml) previously identified by RNA testing of 16-member plasma pools. HIV-1 RNA was detectable in 128-member pools for all 21 specimens; however, one pool created from a specimen with 1,827 copies/ml was nonreactive in one of three replicates.

journal_name

J Clin Microbiol

authors

Sullivan TJ,Patel P,Hutchinson A,Ethridge SF,Parker MM

doi

10.1128/JCM.00650-11

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

3667-8

issue

10

eissn

0095-1137

issn

1098-660X

pii

JCM.00650-11

journal_volume

49

pub_type

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