Comparison of 17 genome types of adenovirus type 3 identified among strains recovered from six continents.

Abstract:

:Restriction endonucleases BamHI, BclI, BglI, BglII, BstEII, EcoRI, HindIII, HpaI, SalI, SmalI, XbalI, and XholI were used to analyze 61 selected strains of adenovirus type 3 (Ad3) isolated from Africa, Asia, Australia, Europe, North America, and South America. It was noted that the use of BamHI, BclI, BglII, HpaI, SalI, and SmaI was sufficient to distinguish 17 genome types; 13 of them were newly identified. All 17 Ad3 genome types could be divided into three genomic clusters. Genome types of Ad3 cluster 1 occurred in Africa, Europe, South America, and North America. Genomic cluster 2 was identified in Africa; genomic cluster 3 was identified in Africa, Asia, Australia, Europe (a few), and North America. This was of interest because 15 identified genome types of Ad7 could also be divided into three genomic clusters. The degree of genetic relatedness between the 17 Ad3 and the 15 Ad7 genome types was analyzed and was expressed in a three-dimensional model.

journal_name

J Clin Microbiol

authors

Li QG,Wadell G

doi

10.1128/JCM.26.5.1009-1015.1988

subject

Has Abstract

pub_date

1988-05-01 00:00:00

pages

1009-15

issue

5

eissn

0095-1137

issn

1098-660X

journal_volume

26

pub_type

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