Breast carcinoma in young women.


OBJECTIVE:To estimate the incidence of breast carcinoma and survival in patients younger than 25 years old, and to describe presenting clinical signs and symptoms of breast cancer in this age group. METHODS:A population-based descriptive study and case review in Olmsted County, Minnesota, was conducted using the resources of the Rochester Epidemiology Project. Participants were Olmsted County girls and women younger than 25 years old with histopathologically confirmed breast carcinoma diagnosed between 1935 and 2005. Nonresidents who presented to a medical facility within Olmsted County during this time period were included in some portions of the analysis. Main outcome measures were age-adjusted incidence, 5-year survival, and clinical presentation of breast carcinoma in girls and women younger than 25 years of age. RESULTS:With four breast carcinomas observed in Olmsted County residents over 1,201,539 person-years, the annual age-adjusted incidence of breast cancer in this population was 3.2 per million (95% confidence interval, 0.1-6.2). All four cancers occurred in the 20- to 24-year age group (age-specific incidence, 16.2 per million). Eight additional cases of breast carcinoma were identified in nonresidents. Delay in diagnosis was common. All had at least one feature worrisome for an aggressive neoplasm identified in their clinical history, on physical examination or by imaging. CONCLUSION:Breast carcinoma in young women is very rare, associated with delayed diagnosis, and usually associated with concerning features requiring biopsy. LEVEL OF EVIDENCE:III.


Obstet Gynecol


Simmons PS,Jayasinghe YL,Wold LE,Melton LJ 3rd




Has Abstract


2011-09-01 00:00:00














  • Simple antenatal preparation to improve breastfeeding practice: a randomized controlled trial.

    abstract:OBJECTIVE:To address the impact of simple antenatal educational interventions on breastfeeding practice. METHODS:A randomized controlled trial was carried out in a tertiary referral center from May 2002 to December 2004. A random sample of eligible low-risk antenatal patients was recruited from clinics in the National...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验


    authors: Mattar CN,Chong YS,Chan YS,Chew A,Tan P,Chan YH,Rauff MH

    更新日期:2007-01-01 00:00:00

  • Factors related to successful misoprostol treatment for early pregnancy failure.

    abstract:OBJECTIVE:To identify potential predictors for treatment success in medical management with misoprostol for early pregnancy failure. METHODS:We conducted a planned secondary analysis of data from a multicenter trial that compared medical and surgical management of early pregnancy failure. Medical management consisted ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Creinin MD,Huang X,Westhoff C,Barnhart K,Gilles JM,Zhang J,National Institute of Child Health and Human Development Management of Early Pregnancy Failure Trial.

    更新日期:2006-04-01 00:00:00

  • Prostaglandin E2 analogue sulprostone for treatment of atonic postpartum hemorrhage.

    abstract:OBJECTIVES:Use of prostaglandins, including sulprostone (an E2 analog), is recommended for second-line uterotonic treatment of atonic postpartum hemorrhage and might be considered as an indicator of quality of care in severe atonic postpartum hemorrhage management. Our objective was to estimate whether sulprostone was ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究


    authors: Schmitz T,Tararbit K,Dupont C,Rudigoz RC,Bouvier-Colle MH,Deneux-Tharaux C,Pithagore6 group.

    更新日期:2011-08-01 00:00:00

  • Abdominal wall repair with polypropylene mesh in pregnancy.

    abstract::A woman in her 34th week of gestation required emergency appendectomy for perforation, with postoperative wound dehiscence secondary to fasciitis and tension on the suture line. Polypropylene mesh was used to repair the abdominal wall. Fetal distress necessitated a cesarean section. The mother and child both survived ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Martin LF,Barry MG,Peeno DO,Fry DE

    更新日期:1985-07-01 00:00:00

  • Isolation of Chlamydia trachomatis from sexually abused female adolescents.

    abstract::Cultures for Chlamydia trachomatis were obtained from 127 female adolescents (13-17 years of age) evaluated for reported sexual abuse. The rate of positive cultures for C trachomatis in this population was 14% (18 of 127). Neisseria gonorrhoeae was found in 12% (15 of 127) of these patients. All but two of the culture...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Dattel BJ,Landers DV,Coulter K,Hinton J,Sweet RL,Schachter J

    更新日期:1988-08-01 00:00:00

  • Committee opinion no. 507: human trafficking.

    abstract::Human trafficking is a widespread problem with estimates ranging from 14,000 to 50,000 individuals trafficked into the United States annually. This hidden population involves the commercial sex industry, agriculture, factories, hotel and restaurant businesses, domestic workers, marriage brokers, and some adoption firm...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章



    更新日期:2011-09-01 00:00:00

  • The effect of glucagon on spontaneous contractility of isolated pregnant uterine muscle.

    abstract:OBJECTIVE:To determine whether glucagon has relaxant effects on the spontaneous contractions of term pregnant human uterine smooth muscle in an isolated preparation. METHODS:Myometrial specimens were excised from the upper incisional surface of the lower uterine segment in seven women during elective cesarean delivery...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Shin YK,Collea JV,Kim YD

    更新日期:1996-11-01 00:00:00

  • Factors predicting successful labor induction.

    abstract:OBJECTIVE:To evaluate maternal parity, the sonographic measurement of cervical length, and the five components of the Bishop score to determine which factors best predict the length of latent-phase labor in women undergoing labor induction. METHODS:Cervical position, cervical consistency, cervical effacement, cervical...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Watson WJ,Stevens D,Welter S,Day D

    更新日期:1996-12-01 00:00:00

  • Primary invasive carcinoma of the vagina.

    abstract::A retrospective study of 29 patients with invasive carcinoma of the vagina was completed at The Milton S. Hershey Medical Center, Pennsylvania State University, for a ten-year period from 1976-1986. The overall incidence was 1.3% of all gynecologic malignancies. Twenty-four patients (83%) had squamous cell carcinoma a...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Manetta A,Pinto JL,Larson JE,Stevens CW Jr,Pinto JS,Podczaski ES

    更新日期:1988-07-01 00:00:00

  • Trisomy 21, fetal hydrops, and anemia: prenatal diagnosis of transient myeloproliferative disorder?

    abstract:BACKGROUND:Aneuploidy is frequently cited as an etiology of hydrops fetalis. Traditionally, associated anomalies (specifically cardiovascular abnormalities) have been postulated as the causative factor. CASES:We report two cases of severe anemia associated with hydrops in fetuses that later proved to have Down syndrom...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Hendricks SK,Sorensen TK,Baker ER

    更新日期:1993-10-01 00:00:00

  • Cerebral metastases of a choriocarcinoma during pregnancy.

    abstract:BACKGROUND:Cerebral metastasis of choriocarcinoma during pregnancy is rare. Described is the fourth case in the literature. CASE:A pregnant women at 28 weeks' gestation sought care for headaches followed by loss of consciousness. The diagnosis of choriocarcinoma metastases was made on the basis of the combination of c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Picone O,Castaigne V,Ede C,Fernandez H

    更新日期:2003-12-01 00:00:00

  • Ovarian arteriovenous fistula. An unusual cause of abdominal pain.

    abstract::Arteriovenous fistulae of the ovarian artery may develop after gynecologic surgery. A case that occurred 9 years after hysterectomy with bilateral oophorectomy is presented and discussed. It illustrates an unusual cause of left lower quadrant abdominal pain. Surgical removal of the ovarian arteriovenous fistula result...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Swenson WM,Tolstedt GE,Ramos P,Peters CH

    更新日期:1978-01-01 00:00:00

  • Complex atypical endometrial hyperplasia: the risk of unrecognized adenocarcinoma and value of preoperative dilation and curettage.

    abstract:OBJECTIVE:To evaluate whether preoperative dilation and curettage (D&C) lowers the risk of unexpected cancer at hysterectomy. METHODS:Women with complex atypical endometrial hyperplasia on sampling from January 2000 to May 2008 who underwent hysterectomy within 6 months were identified using a pathology database. Pati...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Suh-Burgmann E,Hung YY,Armstrong MA

    更新日期:2009-09-01 00:00:00

  • Maternal morbidity and risk of death at delivery hospitalization.

    abstract:OBJECTIVE:To examine the effect of underlying maternal morbidities on the odds of maternal death during delivery hospitalization. METHODS:We used data that linked birth certificates to hospital discharge diagnoses from singleton live births at 22 weeks of gestation or later during 1995-2003 in New York City. Maternal ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Campbell KH,Savitz D,Werner EF,Pettker CM,Goffman D,Chazotte C,Lipkind HS

    更新日期:2013-09-01 00:00:00

  • Uterine leiomyosarcoma metastatic to the thyroid.

    abstract:BACKGROUND:Uterine leiomyosarcoma is an aggressive tumor that has a propensity for distant metastasis. Distant sites of spread include the lung, liver, brain, and bone. CASE:A woman in her 5th decade was diagnosed with stage IV leiomyosarcoma of the uterus. Distant metastasis in the chest was confirmed by thoracotomy ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Leath CA 3rd,Huh WK,Straughn JM Jr,Conner MG

    更新日期:2002-11-01 00:00:00

  • Deceleration/contraction ratios as an index of fetal health during labor.

    abstract::Internal FHR tracings of 259 patients with variable decelerations and 49 with late decelerations were analyzed for frequency and severity of the pattern in an attempt to correlate with fetal pH or Apgar score at 1 minute. A significant increase in the risk of fetal acidosis was associated with a frequency of greater t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Lin CC,Schulman H,Saldana LR

    更新日期:1978-06-01 00:00:00

  • Diagnosis of chlamydial infection in pregnant women using the Testpack Chlamydia diagnostic kit.

    abstract::We compared the performance of Testpack Chlamydia to tissue culture isolation for detection of endocervical chlamydia in an obstetric clinic population at high risk for infection. Among 227 evaluable patients, 30 tissue culture-confirmed chlamydial infections were found (13.2%). The sensitivity, specificity, and posit...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Grossman JH 3rd,Rivlin ME,Morrison JC

    更新日期:1991-05-01 00:00:00

  • Ultrasonographic measurements of fetal ear.

    abstract:OBJECTIVE:To establish nomograms of fetal ear measurements. Newborns with trisomies have smaller ears than the normal population. This observation led us to believe that ear measurements might be useful in the antenatal prediction of fetuses with abnormal karyotypes. METHODS:Fetal ear length and width were obtained ul...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Shimizu T,Salvador L,Allanson J,Hughes-Benzie R,Nimrod C

    更新日期:1992-09-01 00:00:00

  • Determinants of postoperative outcomes of female genital fistula repair surgery.

    abstract:OBJECTIVE:To determine predictors of fistula repair outcomes 3 months postsurgery. METHODS:We conducted a multicountry prospective cohort study between 2007 and 2010. Outcomes, measured 3 months postsurgery, included fistula closure and residual incontinence in women with a closed fistula. Potential predictors include...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Barone MA,Frajzyngier V,Ruminjo J,Asiimwe F,Barry TH,Bello A,Danladi D,Ganda SO,Idris S,Inoussa M,Lynch M,Mussell F,Podder DC

    更新日期:2012-09-01 00:00:00

  • Umbilical cord plasma cortisol levels in association with pregnancy complications.

    abstract::Cortisol concentrations in umbilical cord plasma at birth were determined in association with pregnancy complications which may affect the time of pulmonary maturation of the fetus or otherwise influence its survival. No statistically significant change in these cortisol levels was observed in either term or premature...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Sybulski S

    更新日期:1977-09-01 00:00:00

  • Discordant middle cerebral artery peak systolic velocity Doppler studies in a fetus with RhD alloimmunization.

    abstract:BACKGROUND:Doppler measurement of the fetal middle cerebral artery peak systolic velocity is a valuable tool in detecting the presence of fetal anemia in Rh-sensitized pregnancies. We present a case in which discordant left and right middle cerebral artery Dopplers complicated clinical management. CASE:An RhD-alloimmu...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Berkley EM,Rappaport VJ,Hurley TJ

    更新日期:2007-08-01 00:00:00

  • Cancer metastatic to the ovary: factors influencing survival.

    abstract::In the period 1950 through 1966, 357 patients with cancer metastatic to the ovaries were treated at the Mayo Clinic. The majority of primary tumors arose in the gastrointestinal tract. Factors influencing survival included the site of the primary cancer, histologic grade of the neoplasm, menstrual status, and the type...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Webb MJ,Decker DG,Mussey E

    更新日期:1975-04-01 00:00:00

  • Enhancing Participation in Depression Care in Outpatient Perinatal Care Settings: A Systematic Review.

    abstract:OBJECTIVE:To examine a wide range of study designs and outcomes to estimate the extent to which interventions in outpatient perinatal care settings are associated with an increase in the uptake of depression care. DATA SOURCES:PubMed, CINAHL, PsycINFO,, and Scopus (EMBASE) were searched for studies ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审


    authors: Byatt N,Levin LL,Ziedonis D,Moore Simas TA,Allison J

    更新日期:2015-11-01 00:00:00

  • Chorioamnionitis and sternoclavicular septic arthritis after drainage of Bartholin gland abscess.

    abstract:BACKGROUND:Complications after drainage of Bartholin gland abscesses in pregnancy are rare. CASE:A 29-year-old primigravid at 35 weeks of gestation with dichorionic-diamniotic twins underwent Bartholin gland abscess drainage. Afterward, she reported shoulder pain and became febrile. Examination revealed maternal and f...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Kelly JC,Jia X,Vindenes T,Urato AC

    更新日期:2014-08-01 00:00:00

  • Maternal death in a patient with Eisenmenger's syndrome.

    abstract::A pregnant patient with Eisenmenger's syndrome is reported. The hemodynamic data gathered during this pregnancy suggest that decreased peripheral vascular resistance and reflex bradycardia secondary to postural changes could be of extreme importance in contributing to the extremely high maternal mortality. Suggestions...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Arias F

    更新日期:1977-07-01 00:00:00

  • A five-year experience with terbutaline for preterm labor: low rate of severe side effects.

    abstract::The medical records of 330 patients treated with terbutaline infusion for the inhibition of preterm labor were reviewed over a five-year period. In patients with intact membranes the results were uniformly good, particularly when treatment was instituted before the 30th week. Half these patients had a prolonged labor ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Ingemarsson I,Bengtsson B

    更新日期:1985-08-01 00:00:00

  • Inhibition of premature labor by terbutaline.

    abstract::Terbutaline was administered to 50 women, all diagnosed as being in labor prior to 36 weeks' gestation. In 47, uterine activity was initially arrested with intravenous therapy. The infusion rate required to arrest uterine activity ranged from 10 to 80 microgram/min and 21 of the 50 patients (42%) required more than on...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Wallace RL,Caldwell DL,Ansbacher R,Otterson WN

    更新日期:1978-04-01 00:00:00

  • The effect of chorioamnionitis on the developmental outcome of preterm infants at one year.

    abstract::This report investigates the effect of chorioamnionitis on infant mental and psychomotor development at one year through the prospective study of 698 preterm pregnancies complicated by premature rupture of membranes and managed expectantly without antenatal corticosteroids or tocolytic agents. Ninety-two mothers (13%)...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Morales WJ

    更新日期:1987-08-01 00:00:00

  • Adverse pregnancy outcomes related to advanced maternal age compared with smoking and being overweight.

    abstract:OBJECTIVE:To investigate the association between advanced maternal age and adverse pregnancy outcomes and to compare the risks related to advanced maternal age with those related to smoking and being overweight or obese. METHODS:A population-based register study including all nulliparous women aged 25 years and older ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Waldenström U,Aasheim V,Nilsen ABV,Rasmussen S,Pettersson HJ,Shytt E

    更新日期:2014-01-01 00:00:00

  • Fracture healing in estrogen-treated and castrated rats.

    abstract::The healing of a midfibular fracture was studied in mature rats. The strength of the healing fracture was determined by a constant speed-driven tensiometer which measured the force required to separate the healing callus. The breaking strength of the healing experimental fracture was ascertained in control, estrogen-t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章


    authors: Blythe JG,Buchsbaum HJ

    更新日期:1976-09-01 00:00:00