Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesions.

Abstract:

INTRODUCTION:Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. MATERIALS AND METHODS:41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. RESULTS:Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 x 10(-3) mm(2)/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. CONCLUSIONS:DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.

journal_name

Wien Klin Wochenschr

authors

Sonmez G,Cuce F,Mutlu H,Incedayi M,Ozturk E,Sildiroglu O,Velioglu M,Bashekim CC,Kizilkaya E

doi

10.1007/s00508-011-0053-5

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

655-61

issue

21-22

eissn

0043-5325

issn

1613-7671

journal_volume

123

pub_type

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