Improved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer.

abstract：:The goal of this work was to study the overall genomic diversity of microorganisms of the Dagang high-temperature oilfield (PRC) and to characterize the metabolically active fraction of these populations. At this water-flooded oilfield, the microbial community of formation water from the near-bottom zone of an injecti...

journal_title：Frontiers in microbiology

authors： Nazina TN,Shestakova NM,Semenova EM,Korshunova AV,Kostrukova NK,Tourova TP,Min L,Feng Q,Poltaraus AB

更新日期：2017-04-25 00:00:00

abstract：:Nutrient availability and ratios can play an important role in shaping microbial communities of freshwater ecosystems. The Cuatro Ciénegas Basin (CCB) in Mexico is a desert oasis where, perhaps paradoxically, high microbial diversity coincides with extreme oligotrophy. To better understand the effects of nutrients on ...

journal_title：Frontiers in microbiology

authors： Lee ZM,Poret-Peterson AT,Siefert JL,Kaul D,Moustafa A,Allen AE,Dupont CL,Eguiarte LE,Souza V,Elser JJ

更新日期：2017-05-30 00:00:00

abstract：:The mycorrhizal symbiosis between soil fungi and plant roots is a ubiquitous mutualism that plays key roles in plant nutrition, soil health, and carbon cycling. The symbiosis evolved repeatedly and independently as multiple morphotypes [e.g., arbuscular mycorrhizae (AM), ectomycorrhizal (ECM)] in multiple fungal clade...

journal_title：Frontiers in microbiology

authors： Kuo A,Kohler A,Martin FM,Grigoriev IV

更新日期：2014-11-04 00:00:00

abstract：:Toxoplasma gondii is a protozoan parasite with a remarkable neurotropism. We recently showed that T. gondii infection can alter the global metabolism of the cerebral cortex of mice. However, the impact of T. gondii infection on the metabolism of the cerebellum remains unknown. Here we apply metabolomic profiling to di...

journal_title：Frontiers in microbiology

authors： Ma J,He JJ,Hou JL,Zhou CX,Elsheikha HM,Zhu XQ

更新日期：2020-07-10 00:00:00

abstract：:Currently microorganisms are best identified using 16S rRNA and 18S rRNA gene sequencing. However, in recent years matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a potential tool for microbial identification and diagnosis. During the MALDI-TOF MS process, mic...

journal_title：Frontiers in microbiology

authors： Singhal N,Kumar M,Kanaujia PK,Virdi JS

更新日期：2015-08-05 00:00:00

abstract：:The diversity of fungi in grape must and during wine fermentation was investigated in this study by culture-dependent and culture-independent techniques. Carignan and Grenache grapes were harvested from three vineyards in the Priorat region (Spain) in 2012, and nine samples were selected from the grape must after crus...

journal_title：Frontiers in microbiology

authors： Wang C,García-Fernández D,Mas A,Esteve-Zarzoso B

更新日期：2015-10-23 00:00:00

abstract：:Prosthetic joint replacement failure has a huge impact on quality of life and hospitalization costs. A leading cause of prosthetic joint infection is bacteria-forming biofilm on the surface of orthopedic devices. Staphylococcus epidermidis is an emergent, low-virulence pathogen implicated in chronic infections, barely...

journal_title：Frontiers in microbiology

authors： Bottagisio M,Soggiu A,Piras C,Bidossi A,Greco V,Pieroni L,Bonizzi L,Roncada P,Lovati AB

更新日期：2019-09-06 00:00:00

abstract：:In Liberibacter asiaticus, PrbP is an important transcriptional accessory protein that was found to regulate gene expression through interactions with the RNA polymerase β-subunit and a specific sequence on the promoter region. It was found that inactivation of PrbP, using the inhibitor tolfenamic acid, resulted in a ...

journal_title：Frontiers in microbiology

authors： Pan L,Gardner CL,Pagliai FA,Gonzalez CF,Lorca GL

更新日期：2017-08-23 00:00:00

abstract：:To date, genes identified and transcriptionally regulated by the AirSR TCS have been involved in energy production and cellular homeostasis of the staphylococcal cell. It is well accepted that the state of cellular metabolism impacts the expression of virulence factors in Staphylococcus aureus. For this reason, we con...

journal_title：Frontiers in microbiology

authors： Hall JW,Yang J,Guo H,Ji Y

更新日期：2015-07-03 00:00:00

abstract：:Salmonella enterica serotypes are invasive enteric pathogens spread through fecal contamination of food and water sources, and represent a constant public health threat around the world. The symptoms associated with salmonellosis and typhoid disease are largely due to the host response to invading Salmonella, and to t...

journal_title：Frontiers in microbiology

authors： Hallstrom K,McCormick BA

更新日期：2011-04-29 00:00:00

abstract：:Experiments with different phytoplankton densities in lake samples showed that a high biomass increases the rate of hydrogen peroxide (HP) degradation and decreases the effectiveness of HP in the selective suppression of dominant cyanobacteria. However, selective application of HP requires usage of low doses only, acc...

journal_title：Frontiers in microbiology

authors： Weenink EF,Luimstra VM,Schuurmans JM,Van Herk MJ,Visser PM,Matthijs HC

更新日期：2015-07-22 00:00:00

abstract：:Zika virus (ZIKV) infection in humans has been associated with congenital malformations and other neurological disorders, such as Guillain-Barré syndrome. The mechanism(s) of ZIKV intrauterine transmission, the cell types involved, the most vulnerable period of pregnancy for severe outcomes from infection and other ph...

journal_title：Frontiers in microbiology

authors： de Noronha L,Zanluca C,Burger M,Suzukawa AA,Azevedo M,Rebutini PZ,Novadzki IM,Tanabe LS,Presibella MM,Duarte Dos Santos CN

更新日期：2018-09-25 00:00:00

abstract：:Swine grown under commercial conditions are vulnerable to environmental exposure to several viruses, which may cause infectious diseases and spread easily and rapidly, resulting in significant economic losses in animal husbandry. Previous studies have suggested that probiotics seem to be a new and promising alternativ...

journal_title：Frontiers in microbiology

authors： Chang-Liao WP,Lee A,Chiu YH,Chang HW,Liu JR

更新日期：2020-07-15 00:00:00

abstract：:Microorganisms are an essential component of cheeses and play important roles during both cheese manufacture and ripening. Both starter and secondary flora modify the physical and chemical properties of cheese, contributing and reacting to changes that occur during the manufacture and ripening of cheese. As the compos...

journal_title：Frontiers in microbiology

authors： Neviani E,Bottari B,Lazzi C,Gatti M

更新日期：2013-02-28 00:00:00

abstract：:Panax ginseng rusty root rot caused by the Ilyonectria species complex is a devastating disease, and it is one of the main factors contributing to the difficulty in continual cropping. Rusty root rot occurs in all ginseng fields, but little is known about the taxonomy of the fungal pathogen complex, especially Ilyonec...

journal_title：Frontiers in microbiology

authors： Guan YM,Ma YY,Jin Q,Wang QX,Liu N,Fu YP,Zhang YY,Li Y

更新日期：2020-12-16 00:00:00

abstract：:The threat of bioterrorism and pandemics has highlighted the urgency for rapid and reliable bioaerosol detection in different environments. Safeguarding against such threats requires continuous sampling of the ambient air for pathogen detection. In this study we investigated the efficacy of the Airborne Sample Analysi...

journal_title：Frontiers in microbiology

authors： Sharma A,Clark E,McGlothlin JD,Mittal SK

更新日期：2015-05-27 00:00:00

abstract：:PP2A-like phosphatases share high homology with PP2A enzymes and are composed of a catalytic subunit and a regulatory subunit. In Candida albicans, the PP2A-like catalytic subunit SIT4 regulates cell growth, morphogenesis, and virulence. However, the functions of its regulatory subunits remain unclear. Here, by homolo...

journal_title：Frontiers in microbiology

authors： Han Q,Pan C,Wang Y,Zhao L,Wang Y,Sang J

更新日期：2019-12-20 00:00:00

abstract：:Alphaviruses and flaviviruses are important human pathogens that include Chikungunya virus (CHIKV), Dengue virus (DENV), and Zika virus (ZIKV), which can cause diseases in humans ranging from arthralgia to hemorrhagic fevers and microcephaly. It was previously shown that treatment with surface layer (S-layer) protein,...

journal_title：Frontiers in microbiology

authors： Prado Acosta M,Geoghegan EM,Lepenies B,Ruzal S,Kielian M,Martinez MG

更新日期：2019-04-16 00:00:00

abstract：:Parasites are key drivers of phytoplankton bloom dynamics and related aquatic ecosystem processes. Yet, the dearth of morphological and molecular information hinders the assessment of their diversity and ecological role. Using single-cell techniques, we characterise morphologically and molecularly, intracellular paras...

journal_title：Frontiers in microbiology

authors： Garvetto A,Nézan E,Badis Y,Bilien G,Arce P,Bresnan E,Gachon CMM,Siano R

更新日期：2018-12-03 00:00:00

abstract：:Sphingolipids form of a unique and complex group of bioactive lipids in fungi. Structurally, sphingolipids of fungi are quite diverse with unique differences in the sphingoid backbone, amide linked fatty acyl chain and the polar head group. Two of the most studied and conserved sphingolipid classes in fungi are the gl...

journal_title：Frontiers in microbiology

authors： Singh A,Del Poeta M

更新日期：2016-04-14 00:00:00

abstract：:Flammeovirga pacifica strain WPAGA1 is a Gram-negative, polysaccharide-degrading bacterium isolated from the marine sediment of the West Pacific Ocean. This strain is a cosmopolitan marine bacterium that uses complex polysaccharides as exclusive source of carbon and energy and plays a key role in the marine carbon cyc...

journal_title：Frontiers in microbiology

authors： Gao B,Jin M,Li L,Qu W,Zeng R

更新日期：2017-04-10 00:00:00

abstract：:Salmonella is one of the most frequently reported causes of foodborne illness worldwide. Non-typhoidal serovars cause gastroenteritis in humans. Salmonella can grow on surfaces forming biofilms, contributing to its persistence since biofilms are difficult to eradicate due to the high resistance to antimicrobials and d...

journal_title：Frontiers in microbiology

authors： Paytubi S,Cansado C,Madrid C,Balsalobre C

更新日期：2017-11-07 00:00:00

abstract：:Clonostachys rosea is a biological control agent against Fusarium graminearum in small grain cereals and maize. Infections with F. graminearum do not only reduce the yield but, due to the production of mycotoxins, also affect the entire value chain of food and feed. In addition, production of other secondary metabolit...

journal_title：Frontiers in microbiology

authors： Gimeno A,Sohlberg E,Pakula T,Limnell J,Keller B,Laitila A,Vogelgsang S

更新日期：2019-07-16 00:00:00

abstract：:Biofilms are the dominant form of microbial loading (and organic material) within drinking water distribution systems (DWDS), yet our understanding of DWDS microbiomes is focused on the more easily accessible bulk-water. Disinfectant residuals are commonly provided to manage planktonic microbial activity in DWDS to sa...

journal_title：Frontiers in microbiology

authors： Fish KE,Boxall JB

更新日期：2018-10-23 00:00:00

abstract：:Adequate comparisons of DNA and cDNA libraries from complex environments require methods for co-extraction of DNA and RNA due to the inherent heterogeneity of such samples, or risk bias caused by variations in lysis and extraction efficiencies. Still, there are few methods and kits allowing simultaneous extraction of ...

journal_title：Frontiers in microbiology

authors： Lim NY,Roco CA,Frostegård Å

更新日期：2016-10-18 00:00:00

abstract：:The time-to-result for culture-based microorganism recovery and phenotypic antimicrobial susceptibility testing necessitates initial use of empiric (frequently broad-spectrum) antimicrobial therapy. If the empiric therapy is not optimal, this can lead to adverse patient outcomes and contribute to increasing antibiotic...

journal_title：Frontiers in microbiology

authors： Pesesky MW,Hussain T,Wallace M,Patel S,Andleeb S,Burnham CD,Dantas G

更新日期：2016-11-28 00:00:00

abstract：:As a natural severe contaminant of stored grains and other crops worldwide, Aspergillus flavus can produce aflatoxins (AFs), the most powerful naturally producing toxic and hepatocarcinogenic compounds. AFs production is regulated by diverse factors including AFs cluster genes, transcription factors, regulators, and e...

journal_title：Frontiers in microbiology

authors： Li X,Jiang Y,Ma L,Ma X,Liu Y,Shan J,Ma K,Xing F

更新日期：2020-07-14 00:00:00

abstract：:The bacterial catabolism of aromatic compounds has considerable promise to convert lignin depolymerization products to commercial chemicals. Alkylphenols are a key class of depolymerization products whose catabolism is not well-elucidated. We isolated Rhodococcus rhodochrous EP4 on 4-ethylphenol and applied genomic an...

journal_title：Frontiers in microbiology

authors： Levy-Booth DJ,Fetherolf MM,Stewart GR,Liu J,Eltis LD,Mohn WW

更新日期：2019-08-20 00:00:00

abstract：:Background: BCG protection is suboptimal and there is significant interest to develop new tuberculosis (TB) vaccines. However, there are significant limitations of the current vaccine evaluation systems in the mouse model. Here, we developed a BCG-challenge rabbit skin model as a new way to evaluate the protective eff...

journal_title：Frontiers in microbiology

authors： Chen H,Liu X,Ma X,Wang Q,Yang G,Niu H,Li S,He B,He S,Dannenberg AM Jr,Zhu B,Zhang Y

更新日期：2017-05-17 00:00:00

abstract：:Bacteria carrying antibiotic resistance genes (ARGs) are naturally prevalent in lotic ecosystems such as rivers. Their ability to spread in anthropogenic waters could lead to the emergence of multidrug-resistant bacteria of clinical importance. For this study, three regions of the Isabela river, an important urban riv...

journal_title：Frontiers in microbiology

authors： Calderón VV,Bonnelly R,Del Rosario C,Duarte A,Baraúna R,Ramos RT,Perdomo OP,Rodriguez de Francisco LE,Franco EF

更新日期：2021-01-13 00:00:00