Identification of the Tolfenamic Acid Binding Pocket in PrbP from Liberibacter asiaticus.

abstract：:The human gastric lumen is one of the most hostile environments of the human body suspected to be sterile until the discovery of Helicobacter pylori (H.p.). State of the art next generation sequencing technologies multiply the knowledge on H.p. functional genomics as well as on the colonization of supposed sterile hum...

journal_title：Frontiers in microbiology

authors： Klymiuk I,Bilgilier C,Stadlmann A,Thannesberger J,Kastner MT,Högenauer C,Püspök A,Biowski-Frotz S,Schrutka-Kölbl C,Thallinger GG,Steininger C

更新日期：2017-12-14 00:00:00

abstract：:Vibrio cholerae, the etiological agent of cholera, employs quorum sensing (QS) pathways to control the expression of virulence factors, including the production of cholera toxin and biofilm formation. Acquired antibiotic resistance in V. cholerae draws attention to the development of novel therapeutics that counteract...

journal_title：Frontiers in microbiology

authors： Sarveswari HB,Kalimuthu S,Shanmugam K,Neelakantan P,Solomon AP

更新日期：2020-07-10 00:00:00

abstract：:Cyclic lipodepsipeptides produced by Pseudomonas spp. (Ps-CLPs) are biosurfactants that constitute a diverse class of versatile bioactive natural compounds with promising application potential. While chemically diverse, they obey a common structural blue-print, allowing the definition of 14 distinct groups with multip...

journal_title：Frontiers in microbiology

authors： Geudens N,Martins JC

更新日期：2018-08-14 00:00:00

abstract：:Tetrodotoxin (TTX) is one of the most potent naturally occurring compounds and is responsible for many human intoxications worldwide. Paphies australis are endemic clams to New Zealand which contain varying concentrations of TTX. Research suggests that P. australis accumulate the toxin exogenously, but the source rema...

journal_title：Frontiers in microbiology

authors： Biessy L,Pearman JK,Smith KF,Hawes I,Wood SA

更新日期：2020-08-05 00:00:00

abstract：:We characterized the mechanism of fluoroquinolone-resistance in two isolates of Streptococcus pseudopneumoniae having fluoroquinolone-efflux as unique mechanism of resistance. Whole genome sequencing and genetic transformation experiments were performed together with phenotypic determinations of the efflux mechanism. ...

journal_title：Frontiers in microbiology

authors： Alvarado M,Martín-Galiano AJ,Ferrándiz MJ,Zaballos Á,de la Campa AG

更新日期：2017-10-26 00:00:00

abstract：:Schistosomiasis japonica is one of the most prevalent parasitic diseases in China. The scarcity of effective diagnostic tools is a major factor that contributes to the high prevalence of schistosomiasis japonica. SjSP-13 is a promising serological diagnostic biomarker of the disease. However, it is unclear whether pol...

journal_title：Frontiers in microbiology

authors： Xu X,Cui X,Zhu L,Li Z,Zhang Y,Ma L,Pan W

更新日期：2018-07-25 00:00:00

abstract：:Genome duplication requires the coordinated activity of a multi-component machine, the replisome. In contrast to the background of metabolic diversity across the bacterial domain, the composition and architecture of the bacterial replisome seem to have suffered few changes during evolution. This immutability underline...

journal_title：Frontiers in microbiology

authors： Beattie TR,Reyes-Lamothe R

更新日期：2015-06-05 00:00:00

abstract：:Sutterella species have been frequently associated with human diseases, such as autism, Down syndrome, and inflammatory bowel disease (IBD), but the impact of these bacteria on health still remains unclear. Especially the interactions of Sutterella spp. with the host are largely unknown, despite of the species being h...

journal_title：Frontiers in microbiology

authors： Hiippala K,Kainulainen V,Kalliomäki M,Arkkila P,Satokari R

更新日期：2016-10-26 00:00:00

abstract：:To obtain full details of gut microbiota, including bacteria, fungi, bacteriophages, and helminths, in giant pandas (GPs), we created a comprehensive microbial genome database and used metagenomic sequences to align against the database. We delineated a detailed and different gut microbiota structures of GPs. A total ...

journal_title：Frontiers in microbiology

authors： Yang S,Gao X,Meng J,Zhang A,Zhou Y,Long M,Li B,Deng W,Jin L,Zhao S,Wu D,He Y,Li C,Liu S,Huang Y,Zhang H,Zou L

更新日期：2018-07-31 00:00:00

abstract：:Marsupials diverged from eutherian mammals about 148 million years ago and represent a unique lineage of mammals with distinctive morphological and reproductive characteristics. Marsupials have significantly shorter gestation periods than eutherians. Pregnancy typically ranges from 15 to 35 days, with young being born...

journal_title：Frontiers in microbiology

authors： Cheng Y,Belov K

更新日期：2017-03-07 00:00:00

abstract：:The dlt operon of Gram-positive bacteria is required for the incorporation of D-alanine esters into cell wall-associated teichoic acids (TAs). Addition of D-alanine to TAs reduces the negative charge of the cell envelope thereby preventing cationic antimicrobial peptides (CAMPs) from reaching their target of action on...

journal_title：Frontiers in microbiology

authors： Kamar R,Réjasse A,Jéhanno I,Attieh Z,Courtin P,Chapot-Chartier MP,Nielsen-Leroux C,Lereclus D,El Chamy L,Kallassy M,Sanchis-Borja V

更新日期：2017-08-03 00:00:00

abstract：:Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in intracellular Ca2+ secretion within CHPV infected cells that fur...

journal_title：Frontiers in microbiology

authors： Verma AK,Ghosh S,Basu A

更新日期：2018-07-06 00:00:00

abstract：:HIV reservoirs persist in infected individuals despite combination antiretroviral therapy and can be identified in secondary lymphoid tissues, in intestinal tissues, in the central nervous system as well as in blood. Clinical trials have begun to explore effects of small molecule interventions to perturb the latent vi...

journal_title：Frontiers in microbiology

authors： Denton PW,Søgaard OS,Tolstrup M

更新日期：2019-08-21 00:00:00

abstract：:During chronic respiratory infections of cystic fibrosis (CF) patients, bacteria adaptively evolve in response to the nutritional and immune environment as well as influence other infecting microbes. The present study was designed to gain insights into the genetic mechanisms underlying adaptation and diversification b...

journal_title：Frontiers in microbiology

authors： Hassan AA,Dos Santos SC,Cooper VS,Sá-Correia I

更新日期：2020-09-25 00:00:00

abstract：:The Spirochaetes species cause many important diseases including syphilis and Lyme disease. Except for their containing a distinctive endoflagella, no other molecular or biochemical characteristics are presently known that are specific for either all Spirochaetes or its different families. We report detailed comparati...

journal_title：Frontiers in microbiology

authors： Gupta RS,Mahmood S,Adeolu M

更新日期：2013-07-30 00:00:00

abstract：Background:Salvador, Bahia (northeastern Brazil), has been identified as the epicenter of Human T-cell leukemia virus Human T-cell leukemia virus (HTLV) type 1 infection in the country. This study aims to estimate the rate of HTLV infection and the geographical distribution of this virus in this state. Methods:All HTL...

journal_title：Frontiers in microbiology

authors： Pereira FM,de Almeida MDCC,Santos FLN,Carreiro RP,Regis-Silva CG,Galvão-Castro B,Grassi MFR

更新日期：2019-05-14 00:00:00

abstract：:Fungi represent a rich source of bioactive metabolites and some are marketed as alternatives to synthetic agrochemicals against plant pathogens. However, the culturability of fungal strains in artificial laboratory conditions is still limited and the standard mono-cultures do not reflect their full spectrum chemical d...

journal_title：Frontiers in microbiology

authors： Oppong-Danquah E,Parrot D,Blümel M,Labes A,Tasdemir D

更新日期：2018-09-06 00:00:00

abstract：:Retroviruses create permanently integrated proviruses that exist in the host genome. Retroviral genomes encode for functionally conserved gag, pro, pol, and env regions, as well as integrase (IN), which is required for retroviral integration. IN mediates viral genome insertion through 3' end processing of the viral DN...

journal_title：Frontiers in microbiology

authors： Bray S,Turnbull M,Hebert S,Douville RN

更新日期：2016-12-01 00:00:00

abstract：:NASA has made great strides in the past five years to develop a suite of instruments for the International Space Station in order to perform molecular biology in space. However, a key piece of equipment that has been lacking is an instrument that can extract nucleic acids from an array of complex human and environment...

journal_title：Frontiers in microbiology

authors： Urbaniak C,Wong S,Tighe S,Arumugam A,Liu B,Parker CW,Wood JM,Singh NK,Skorupa DJ,Peyton BM,Jenson R,Karouia F,Dragon J,Venkateswaran K

更新日期：2020-08-21 00:00:00

abstract：:Aquilaria malaccensis Lam, commonly known as Agarwood, is a highly valuable species used in production of agar oil from its infected wood, which is utilized in pharmaceutical and perfumery industry. Agar oil formation in agarwood takes years through the natural process which is induced by natural or artificial injury ...

journal_title：Frontiers in microbiology

authors： Chhipa H,Kaushik N

更新日期：2017-07-11 00:00:00

abstract：:Campylobacter jejuni has been reported as a major cause of bacterial food-borne enteritides in developed countries during the last decade. Despite its fastidious growth requirements, including low level of oxygen and high level of CO2, this pathogen is able to persist in the environment without permanent loss of its v...

journal_title：Frontiers in microbiology

authors： Turonova H,Haddad N,Hernould M,Chevret D,Pazlarova J,Tresse O

更新日期：2017-05-18 00:00:00

abstract：:Avian paramyxovirus serotype 3 (APMV-3) causes infection in a wide variety of avian species, but it does not cause apparent diseases in chickens. On the contrary, APMV-1, also known as Newcastle disease virus (NDV), can cause severe disease in chickens. Currently, natural low virulence strains of NDV are used as live-...

journal_title：Frontiers in microbiology

authors： Yoshida A,Samal SK

更新日期：2017-04-20 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2018.00516.]. ...

journal_title：Frontiers in microbiology

authors： Zoran T,Sartori B,Sappl L,Aigner M,Sánchez-Reus F,Rezusta A,Chowdhary A,Taj-Aldeen SJ,Arendrup MC,Oliveri S,Kontoyiannis DP,Alastruey-Izquierdo A,Lagrou K,Lo Cascio G,Meis JF,Buzina W,Farina C,Drogari-Apiranthitou M,G

更新日期：2019-01-14 00:00:00

abstract：:The aquatic bird, egret, could carry antibiotic resistance (AR) from a contaminated waterway (Jin River, Chengdu, China) into the surrounding environment (Wangjianglou Park). A systematic study was carried out on the unique environmental dissemination mode of AR mediated by birds. The minimum inhibitory concentrations...

journal_title：Frontiers in microbiology

authors： Wu J,Huang Y,Rao D,Zhang Y,Yang K

更新日期：2018-04-20 00:00:00

abstract：:Influenza virus RNA-dependent RNA polymerase (RdRp) is a heterotrimer of three viral proteins, PB1, PB2, and PA and is involved in both transcription and replication of the negative strand of the viral RNA (vRNA) genome. RdRp is multifunctional, possessing RNA polymerase, cap binding, and endonuclease activities. The ...

journal_title：Frontiers in microbiology

authors： Miyake Y,Ishii K,Honda A

更新日期：2017-02-09 00:00:00

abstract：:Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis, harbors two separate T6SSs on chromosomes 1 and 2, i.e., T6SS1 (VP1386-1420) and T6SS2 (VPA1025-1046). T6SS1 contains at least 7 putative operons: VP1386-1387, VP1388-1390, VP1392-1391, VP1393-1406, VP1400-1406, VP1409-1407, and VP1410-1...

journal_title：Frontiers in microbiology

authors： Zhang Y,Gao H,Osei-Adjei G,Zhang Y,Yang W,Yang H,Yin Z,Huang X,Zhou D

更新日期：2017-10-16 00:00:00

abstract：:Enterococcus faecalis has controversial status due to its emerging role in nosocomial infections, while some strains with beneficial effects are used as probiotics and starter cultures in dairy industry. These bacteria can be found as resident or transient germs in the gut or on skin, where they are continually expose...

journal_title：Frontiers in microbiology

authors： Cambronel M,Nilly F,Mesguida O,Boukerb AM,Racine PJ,Baccouri O,Borrel V,Martel J,Fécamp F,Knowlton R,Zimmermann K,Domann E,Rodrigues S,Feuilloley M,Connil N

更新日期：2020-07-24 00:00:00

abstract：:Interactions with microbes affect many aspects of animal biology, including immune system development, nutrition and health. In vertebrates, the gut microbiota is dominated by a small subset of phyla, but the species composition within these phyla is typically not conserved. Moreover, several recent studies have shown...

journal_title：Frontiers in microbiology

authors： Ellegaard KM,Engel P

更新日期：2016-09-21 00:00:00

abstract：:RNA silencing mediated by microRNAs (miRNAs) is a recently discovered gene regulatory mechanism involved in various aspects of biology, such as development, cell differentiation and proliferation, and innate immunity against viral infections. miRNAs, which are a class of small (21-25 nucleotides) RNAs, target messenge...

journal_title：Frontiers in microbiology

authors： Tsunetsugu-Yokota Y,Yamamoto T

更新日期：2010-10-13 00:00:00

abstract：:Campylobacter jejuni is the leading cause of bacterial foodborne diarrhoeal disease worldwide. Despite the microaerophilic nature of the bacterium, C. jejuni can survive the atmospheric oxygen conditions in the environment. Bacteria that can survive either within a host or in the environment like C. jejuni require var...

journal_title：Frontiers in microbiology

authors： Gundogdu O,da Silva DT,Mohammad B,Elmi A,Wren BW,van Vliet AH,Dorrell N

更新日期：2016-12-26 00:00:00