Abstract:
OBJECTIVE:Previous analyses have suggested center volume is associated with outcome in children undergoing heart surgery. However, data are limited regarding potential mediating factors, including the relationship of center volume with postoperative complications and mortality in those who suffer a complication. We examined this association in a large multicenter cohort. METHODS:Children 0 to 18 years undergoing heart surgery at centers participating in the Society of Thoracic Surgeons Congenital Heart Surgery Database (2006-2009) were included. In multivariable analysis, we evaluated outcomes associated with annual center volume, adjusting for patient factors and surgical risk category. RESULTS:A total of 35 776 patients (68 centers) were included. Overall, 40.6% of patients had ≥1 complication, and the in-hospital mortality rate was 3.9%. The mortality rate in those patients with a complication was 9.0%. In multivariable analysis, lower center volume was significantly associated with higher in-hospital mortality. There was no association of center volume with the rate of postoperative complications, but lower center volume was significantly associated with higher mortality in those with a complication (P = .03 when volume examined as a continuous variable; odds ratio in centers with <150 vs >350 cases per year = 1.59 [95% confidence interval: 1.16-2.18]). This association was most prominent in the higher surgical risk categories. CONCLUSIONS:These data suggest that the higher mortality observed at lower volume centers in children undergoing heart surgery may be related to a higher rate of mortality in those with postoperative complications, rather than a higher rate of complications alone.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Pasquali SK,Li JS,Burstein DS,Sheng S,O'Brien SM,Jacobs ML,Jaquiss RD,Peterson ED,Gaynor JW,Jacobs JPdoi
10.1542/peds.2011-1188subject
Has Abstractpub_date
2012-02-01 00:00:00pages
e370-6issue
2eissn
0031-4005issn
1098-4275pii
peds.2011-1188journal_volume
129pub_type
杂志文章,多中心研究相关文献
PEDIATRICS文献大全abstract:CONTEXT:The optimal oxygen saturation target for extremely preterm infants remains unclear. OBJECTIVE:To systematically review evidence evaluating the effect of lower (85%-89%) versus higher (91%-95%) pulse oxygen saturation (Spo2) target on mortality and neurodevelopmental impairment (NDI) at 18 to 24 months. DATA S...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2016-1609
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:This study evaluates the potential association of vaccination and death in the Vaccine Safety Datalink (VSD). METHODS:The study cohort included individuals ages 9 to 26 years with deaths between January 1, 2005, and December 31, 2011. We implemented a case-centered method to estimate a relative risk (RR) for...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2015-2970
更新日期:2016-03-01 00:00:00
abstract::Diabetic ketoacidosis (DKA) is a life-threatening condition and a major cause of morbidity and mortality in children with type 1 diabetes mellitus. The deficiency of insulin leads to metabolic decompensation, causing hyperglycemia and ketosis that resolves with the administration of insulin and fluids. However, an ind...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0741
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this work was to identify barriers to physical activity in children with asthma and to compare their customary activity levels, BMI and emotional well-being with that of children with other medical conditions. It was hypothesized that children with asthma would have higher BMI and lower levels...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1846
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVES:Health consequences of shaken baby syndrome, or pediatric abusive head trauma (AHT), can be severe and long-lasting. We aimed to estimate the multiyear medical cost attributable to AHT. METHODS:Using Truven Health MarketScan data, 2003-2011, we identified children 0 to 4 years old with commercial or Medicai...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0117
更新日期:2014-07-01 00:00:00
abstract::A workgroup meeting on the use of family history information in pediatric primary care and public health sponsored by the National Center on Birth Defects and Developmental Disabilities at the Centers for Disease Control and Prevention was held February 24 to 25, 2006. The workgroup participants met to discuss how to ...
journal_title:Pediatrics
pub_type:
doi:10.1542/peds.2007-1010H
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Several studies have found decreased cost and length of stay for patients who are cared for by pediatric hospitalists compared with traditional faculty models. The objective of this study was to compare cost and length of stay between a faculty group and 2 separate hospitalist groups in a community teaching h...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-3146
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To update clinical practice guidelines to assist primary care (PC) clinicians in the management of adolescent depression. This part of the updated guidelines is used to address practice preparation, identification, assessment, and initial management of adolescent depression in PC settings. METHODS:By using ...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2017-4081
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Early shared reading and literacy promotion benefits have stimulated international interest in the development of early-years literacy-promotion programs despite limited evidence of effectiveness at a broader population level. OBJECTIVE:To determine whether a population-based primary care literacy promotion...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2009-3043
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To investigate the role of objective and perceived knowledge about condoms in adolescent males' condom use at first intercourse. METHODS:A longitudinal analysis was conducted of data from a nationally representative sample of 404 virgin male adolescents who were aged 15 to 17 years at wave 1 and reported bec...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-0139
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Kernicterus is a rare but devastating condition. The prevention of bilirubin-induced brain injury is based on the detection of infants at risk for developing severe hyperbilirubinemia. In an 18-hospital health system, Intermountain Health Care (IHC), we initiated a program of predischarge bilirubin screening ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2005-1338
更新日期:2006-05-01 00:00:00
abstract::Three siblings with neonatal familial hyperparathyroidism diagnosed at age 4 months, 2 months, and 5 days, respectively, were treated. Hypercalciuria, nephrocalcinosis, and renal tubular acidosis were present in each child. In all three, there were higher responses of serum parathyroid hormone to serum calcium and hig...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Gender-incongruent (GI) youth have high rates of mental health problems. Although gender-affirming medical care (GAMC) provides psychological benefit, some GI youth present to care at older ages. Whether a relationship exists between age of presentation to GAMC and mental health difficulties warrants study. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3600
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:Maternal risk factors for hypospadias are poorly defined, and there is debate about temporal trends in hypospadias prevalence. We examined select maternal characteristics as possible risk factors for hypospadias among male offspring and evaluated yearly prevalence rates in Washington State. METHODS:We perfor...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1552
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:Children with generalized hypermobility of the joints and musculoskeletal complaints frequently visit pediatric clinics, but many show no currently known collagen or other possibly related diseases. Whether the symptoms are confined to the musculoskeletal system is unknown. We assessed whether such children ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.3.e248
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:This study was designed to develop and to test a home-based, guided imagery treatment protocol, using audio and video recordings, that is easy for health care professionals and patients to use, is inexpensive, and is applicable to a wide range of health care settings. METHODS:Thirty-four children, 6 to 15 ye...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2009-0028
更新日期:2009-11-01 00:00:00
abstract::Over-the-counter (OTC) cough and cold medications are marketed widely for relief of common cold symptoms, and yet studies have failed to demonstrate a benefit of these medications for young children. In addition, OTC medications can be associated with significant morbidity and even mortality in both acute overdoses an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.3.e52
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVE:Hospitalization of clinically stable ventilator-dependent children in an intensive care unit (ICU) remains the standard in most pediatric centers. The aim of this study was to determine whether chronically ventilator-dependent children could be hospitalized safely in a non-ICU setting. METHODS:All ventilator...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.2.257
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to document the psychological adjustment of adolescents who were conceived through donor insemination by lesbian mothers who enrolled before these offspring were born in the largest, longest running, prospective, longitudinal study of same-sex-parented families. METHODS:Betwe...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-3153
更新日期:2010-07-01 00:00:00
abstract::Echocardiographic evaluation of left ventricular (LV) performance was performed in 41 children during and following anthracycline chemotherapy. Prior to treatment LV function was normal in all patients; LV shortening fraction was 35.2 +/- 0.7% and percent of predicted velocity of circumferential fiber shortening was 1...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::As part of a multicenter collaborative study, M-mode echocardiograms were obtained shortly after birth on 3,559 premature infants with birth weight less than or equal to 1,750 g. Of these infants, 1,496 did not develop a cardiac murmur or other signs of a "hemodynamically significant" patent ductus arteriosus (PDA). E...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:The growth of infants with atopic dermatitis (AD) has been poorly investigated based on the early type of feeding. The aim of this study was to assess the growth pattern of AD infants during the first 12 months of life in comparison to healthy infants, according to the early type of feeding (breastfed or nonb...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.5.e73
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To verify and determine the cause of an increase in the referral of infants with plagiocephaly without synostosis (PWS) to a single tertiary craniofacial center. DESIGN:A chart review was performed for 269 infants with a diagnosis of PWS who presented to a single tertiary craniofacial center between 1979 and...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVES:The current study is a 1-year follow-up analysis of data from a randomized controlled trial of Enhanced Milieu Teaching (EMT) for toddlers with language delays. Outcomes and predictors of child language and parent intervention implementation were examined 6 and 12 months after the end of the intervention. M...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2016-3646
更新日期:2017-11-01 00:00:00
abstract:UNLABELLED:Because late repair of coarctation of the aorta (COA) is associated with premature cardiovascular disease in adult life, early detection and treatment is important. OBJECTIVES:To determine the timing of referral to see whether early detection of COA has improved in the past decade, to evaluate the pattern o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:CONTEXT:The effectiveness of many interventions aimed at reducing the risk of retinopathy has not been well established. OBJECTIVE:To estimate the effectiveness of nutritional interventions, oxygen saturation targeting, blood transfusion management, and infection prevention on the incidence of retinopathy of prematuri...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1542/peds.2015-3387
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:The goal was to determine whether patients seen in a referral clinic are experiencing initial allergic reactions to peanuts earlier, compared with a similar population profiled at a different medical center 10 years ago, and to investigate other changes in clinical characteristics of the patients between the ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-0350
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:Despite epidemiologic evidence to the contrary, claims of an association between measles-mumps-rubella vaccination and the development of autism have persisted. Such claims are based primarily on the identification of measles virus nucleic acids in tissues and body fluids by polymerase chain reaction. We sou...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1262
更新日期:2006-10-01 00:00:00
abstract::Disasters disproportionally affect vulnerable, technology-dependent people, including preterm and critically ill newborn infants. It is important for health care providers to be aware of and prepared for the potential consequences of disasters for the NICU. Neonatal intensive care personnel can provide specialized exp...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-0507
更新日期:2017-05-01 00:00:00
abstract::The factors associated with submersion events among less than 20-year-old persons that occurred in King County from 1974 to 1983 were studied to focus prevention efforts. Near-drowning (n = 103) and drowning (n = 96) victims were identified from medical examiners' reports, paramedics' reports, and hospital discharge r...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00